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The map label for this gene is pdxY [H]

Identifier: 16272354

GI number: 16272354

Start: 426096

End: 426962

Strand: Reverse

Name: pdxY [H]

Synonym: HI0405

Alternate gene names: 16272354

Gene position: 426962-426096 (Counterclockwise)

Preceding gene: 16272355

Following gene: 16272353

Centisome position: 23.33

GC content: 39.56

Gene sequence:

>867_bases
ATGAAAAACGTACTTTCGATCCAATCCCACGTAGTCTATGGTTTTGCAGGTAACAAATCCGCGACTTTTCCAATGCAGTT
GTTAGGCGTAGATGTATGGGCATTAAATACCGTTCAATTTTCTAATCACACACAATACGGAAAATGGACAGGTATGGTCA
TTCCACAAGAACAAATCCGAGAAATTGTAACTGGACTTGATAATATTGAAAAACTACAAGAATGTGATGCCTTACTATCA
GGTTACTTAGGATCTGCGGAACAAGTCGATCAAATTCTTTTTGCCTTAGAACAAATCAAACTGCGTAATCCCAATGCGCT
TTATTTATGCGACCCTGTAATGCCACATCCGAAAAAAATCTGCGTAGTTGCCAATGGCGTTCGCGAAGCACTTATTGAAA
AAGCCATTCCAGTGGCGGATATTATGACGCCAAACTTACACGAATTGCGTCAGCTAACCGAATTCCCAATTAATACCTTT
GACGATGTATTAAAAGCAGTGAATGCGTTGATTGCAAAAGGCGTGAAGAAAGTTCTCGTTAAACATTTAGGCAGTGCGGG
TAAAATCAACGATCCTGATACATTTGAAATTATTATGGCAACCCCAGAGGGTGTTTGGCATTTAAGCCGTCCACTTTATC
AATTCAACTTTGAACCAGTGGGCGTGGGCGATTTAATCGCAGGTACATTCTTAGCGAATTTGCTCAATGGAAAATCTGAT
GTTGAAGCTTTTGAAGCAATGAATAATGAAGTGGCAGGCGTAATGAAAACCACCTTTGAACTGGGTTCTTACGAATTACA
AACGATTGCTGCACGTTTTGAAATTCTTAATCCAAGCAGCAATTATAAAGCTGAAAAAGTTGCCTAA

Upstream 100 bases:

>100_bases
ACGTTTAATGTCTTACGGTTATTGCTAACTAACATTCTAAAAGAGCGGTGATTTTTACCGCTCTTTTTTGATCTAAATAT
ACAACAAAGGAGAAAATATA

Downstream 100 bases:

>100_bases
TGGATTTACTTTCAGACATTGAAAAACAACTCCAAAAAGCCACCGCTCAAGCATTTCTTATTGCCTTGAGTGGTGGTTTA
GATTCCACTGTACTTCTTTC

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKNVLSIQSHVVYGFAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPQEQIREIVTGLDNIEKLQECDALLS
GYLGSAEQVDQILFALEQIKLRNPNALYLCDPVMPHPKKICVVANGVREALIEKAIPVADIMTPNLHELRQLTEFPINTF
DDVLKAVNALIAKGVKKVLVKHLGSAGKINDPDTFEIIMATPEGVWHLSRPLYQFNFEPVGVGDLIAGTFLANLLNGKSD
VEAFEAMNNEVAGVMKTTFELGSYELQTIAARFEILNPSSNYKAEKVA

Sequences:

>Translated_288_residues
MKNVLSIQSHVVYGFAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPQEQIREIVTGLDNIEKLQECDALLS
GYLGSAEQVDQILFALEQIKLRNPNALYLCDPVMPHPKKICVVANGVREALIEKAIPVADIMTPNLHELRQLTEFPINTF
DDVLKAVNALIAKGVKKVLVKHLGSAGKINDPDTFEIIMATPEGVWHLSRPLYQFNFEPVGVGDLIAGTFLANLLNGKSD
VEAFEAMNNEVAGVMKTTFELGSYELQTIAARFEILNPSSNYKAEKVA
>Mature_288_residues
MKNVLSIQSHVVYGFAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPQEQIREIVTGLDNIEKLQECDALLS
GYLGSAEQVDQILFALEQIKLRNPNALYLCDPVMPHPKKICVVANGVREALIEKAIPVADIMTPNLHELRQLTEFPINTF
DDVLKAVNALIAKGVKKVLVKHLGSAGKINDPDTFEIIMATPEGVWHLSRPLYQFNFEPVGVGDLIAGTFLANLLNGKSD
VEAFEAMNNEVAGVMKTTFELGSYELQTIAARFEILNPSSNYKAEKVA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=243, Percent_Identity=31.2757201646091, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1787924, Length=288, Percent_Identity=51.0416666666667, Blast_Score=294, Evalue=6e-81,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=28.030303030303, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17507759, Length=301, Percent_Identity=32.890365448505, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17507757, Length=311, Percent_Identity=32.1543408360129, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320806, Length=271, Percent_Identity=33.5793357933579, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324354, Length=246, Percent_Identity=32.9268292682927, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45553007, Length=306, Percent_Identity=33.0065359477124, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31772; Mature: 31772

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVLSIQSHVVYGFAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPQEQIR
CCCHHEEHHEEEEEEECCCCCCCHHHHHHCEEHEEEEEEECCCCCCCCEEEEECCHHHHH
EIVTGLDNIEKLQECDALLSGYLGSAEQVDQILFALEQIKLRNPNALYLCDPVMPHPKKI
HHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEE
CVVANGVREALIEKAIPVADIMTPNLHELRQLTEFPINTFDDVLKAVNALIAKGVKKVLV
EEEEHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KHLGSAGKINDPDTFEIIMATPEGVWHLSRPLYQFNFEPVGVGDLIAGTFLANLLNGKSD
HHCCCCCCCCCCCCEEEEEECCCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHH
VEAFEAMNNEVAGVMKTTFELGSYELQTIAARFEILNPSSNYKAEKVA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MKNVLSIQSHVVYGFAGNKSATFPMQLLGVDVWALNTVQFSNHTQYGKWTGMVIPQEQIR
CCCHHEEHHEEEEEEECCCCCCCHHHHHHCEEHEEEEEEECCCCCCCCEEEEECCHHHHH
EIVTGLDNIEKLQECDALLSGYLGSAEQVDQILFALEQIKLRNPNALYLCDPVMPHPKKI
HHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEE
CVVANGVREALIEKAIPVADIMTPNLHELRQLTEFPINTFDDVLKAVNALIAKGVKKVLV
EEEEHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
KHLGSAGKINDPDTFEIIMATPEGVWHLSRPLYQFNFEPVGVGDLIAGTFLANLLNGKSD
HHCCCCCCCCCCCCEEEEEECCCCCHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHH
VEAFEAMNNEVAGVMKTTFELGSYELQTIAARFEILNPSSNYKAEKVA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA