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The map label for this gene is tolR

Identifier: 16272332

GI number: 16272332

Start: 405071

End: 405490

Strand: Reverse

Name: tolR

Synonym: HI0384

Alternate gene names: 16272332

Gene position: 405490-405071 (Counterclockwise)

Preceding gene: 16272333

Following gene: 16272331

Centisome position: 22.16

GC content: 35.71

Gene sequence:

>420_bases
ATGGCTCGTCGTCAGCGTAAAGCAATTAAATCTGAAATTAATATTGTGCCTTTTTTAGATGTGCTTTTAGTTTTAGTGTT
AATTTTTATGGCAACCGCCCCTATTATTAGTCAAAGCGTTCAAGTTGAATTGCCTGATTCTGTGCAAAGCCAAGAGGTTT
CTAATGAAGATAAAGTACCCGTCATTCTTGAAGTGGCAGGCATTGGAAAATATGCGATTTCTATTGGCGGAGAACGTCAA
GAAGGTTTAACAGAAGAAATGGTTACTCAATTATCTAGACAGGAATTTGATAAGGATAATAATACGCTATTTTTAGTAGG
CGGAGCTAAAGAAGTACCTTATGAAGAAGTGATTAAGGCATTGAATTTACTTCATCTTGCAGGCATTAAATCTGTAGGTT
TAATGACAAATCCCATTTAG

Upstream 100 bases:

>100_bases
GTCAAGCCTTTGGTAAAGCCCCTCACTAAAATATAGGGAAAATTGACCGCACTTTGAAGAAAAAGTGCGGTAAAAATAAG
TTAAAATTTTAGAGGAATAT

Downstream 100 bases:

>100_bases
CTAAGTAGGTAACACGTGCAAAATAATCGACAAAAGAAAGGAATCAATGCTTTTGCTATTTCTATCCTTTTGCACTTTAT
CTTGTTTGGCTTATTGATTT

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQ
EGLTEEMVTQLSRQEFDKDNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI

Sequences:

>Translated_139_residues
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQ
EGLTEEMVTQLSRQEFDKDNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI
>Mature_138_residues
ARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVPVILEVAGIGKYAISIGGERQE
GLTEEMVTQLSRQEFDKDNNTLFLVGGAKEVPYEEVIKALNLLHLAGIKSVGLMTNPI

Specific function: Involved in the tonB-independent uptake of proteins

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family

Homologues:

Organism=Escherichia coli, GI1786959, Length=131, Percent_Identity=62.5954198473283, Blast_Score=142, Evalue=9e-36,
Organism=Escherichia coli, GI1789380, Length=123, Percent_Identity=35.7723577235772, Blast_Score=66, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TOLR_HAEIN (P43769)

Other databases:

- EMBL:   L42023
- EMBL:   U32470
- PIR:   H64064
- RefSeq:   NP_438545.1
- PDB:   2JWK
- PDB:   2JWL
- PDBsum:   2JWK
- PDBsum:   2JWL
- ProteinModelPortal:   P43769
- SMR:   P43769
- GeneID:   949489
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0384
- TIGR:   HI_0384
- HOGENOM:   HBG729503
- OMA:   IITIEIL
- ProtClustDB:   PRK11024
- BioCyc:   HINF71421:HI_0384-MONOMER
- InterPro:   IPR003400

Pfam domain/function: PF02472 ExbD

EC number: NA

Molecular weight: Translated: 15258; Mature: 15127

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcb16928)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVP
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCC
VILEVAGIGKYAISIGGERQEGLTEEMVTQLSRQEFDKDNNTLFLVGGAKEVPYEEVIKA
EEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
LNLLHLAGIKSVGLMTNPI
HHHHHHHCHHHCCCCCCCH
>Mature Secondary Structure 
ARRQRKAIKSEINIVPFLDVLLVLVLIFMATAPIISQSVQVELPDSVQSQEVSNEDKVP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCCC
VILEVAGIGKYAISIGGERQEGLTEEMVTQLSRQEFDKDNNTLFLVGGAKEVPYEEVIKA
EEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHH
LNLLHLAGIKSVGLMTNPI
HHHHHHHCHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895