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The map label for this gene is xerD

Identifier: 16272264

GI number: 16272264

Start: 342649

End: 343542

Strand: Direct

Name: xerD

Synonym: HI0309

Alternate gene names: 16272264

Gene position: 342649-343542 (Clockwise)

Preceding gene: 16272263

Following gene: 16272265

Centisome position: 18.72

GC content: 41.95

Gene sequence:

>894_bases
ATGAAAAATCTTGCGCTCATTGATTTGTTTCTTAACGAATATTGGATTGAAAAAGGGCTTTCAGAAAATACCGTTCAATC
TTATCGTTTGGATTTAACCGCACTTTGTGATTGGTTGGATAAAAACGACTTGTCTTTGGAAACTTTAGATGCTGTTGATT
TGCAAGGTTTTCTAGGAGAGCGTTTGGAGAAAGGTTACAAAGCCACGAGCACTGCGCGAATGTTAAGTGCAATGCGTAAA
CTTTTCCAATATTTATATCGGGAAAAATATCGAGTGGATGATCCAAGTGCGGTGCTAAGTTCGCCTAAATTACCCAGTCG
CTTGCCAAAATATTTAACCGAGCAGCAAGTGTCAGATTTGCTCAATACGCCAAATGTTGAAGTGCCTTTGGAGTTGCGTG
ATAAAGCAATGTTAGAGTTGCTTTATGCAACGGGGCTTCGTGTAACGGAGTTAGTTTCGCTTACGATTGAAAACATGAGC
GTGCAACAAGGCGTGGTGCGAGTGATTGGTAAAGGGAACAAGGAACGTATTGTGCCAATGGGGGAAGAAGCTGCCTATTG
GGTTCGTCAATTTATGCTTTATGGTCGCCCTGTGCTATTAAATGGGCAGAGTTCTGATGTTGTGTTTCCAAGTCAGCGCG
CACAGCAAATGACTCGTCAAACTTTCTGGCATCGTGTAAAACATTATGCCATTCTCGCGGATATTGATGCTGATGCACTT
TCTCCTCACGTTCTTCGCCATGCTTTTGCCACCCATTTAGTAAATCACGGTGCGGATTTACGCGTGGTGCAAATGTTGTT
GGGTCATACAGATTTATCTACAACACAGATTTATACTCACGTGGCAAAAGAAAGATTGAAACGATTGCATGAAAGATTTC
ATCCTAGAGGATAA

Upstream 100 bases:

>100_bases
CATTGCAGCTGCTGCATTTTTTGTGATTCCACGTAAGTTAAATGCCTTTTTGATTGTTCAGCATAAATAGGACGCATTGC
TTTCCTTGTAGAAAAGTAAT

Downstream 100 bases:

>100_bases
TTTCGGGGTAAATTTTTATAGTTTTAAAGATTGATTGTGGATTTCTTATTGATTAATTAATTTGACACGCATCACAAATT
TTGAATAAAAAATTAGACAG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVDLQGFLGERLEKGYKATSTARMLSAMRK
LFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPNVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMTRQTFWHRVKHYAILADIDADAL
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG

Sequences:

>Translated_297_residues
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVDLQGFLGERLEKGYKATSTARMLSAMRK
LFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPNVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMTRQTFWHRVKHYAILADIDADAL
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
>Mature_297_residues
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVDLQGFLGERLEKGYKATSTARMLSAMRK
LFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDLLNTPNVEVPLELRDKAMLELLYATGLRVTELVSLTIENMS
VQQGVVRVIGKGNKERIVPMGEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMTRQTFWHRVKHYAILADIDADAL
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=68.9189189189189, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=34.9315068493151, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1790768, Length=188, Percent_Identity=26.063829787234, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERD_HAEIN (P44630)

Other databases:

- EMBL:   L42023
- PIR:   A64061
- RefSeq:   NP_438476.1
- ProteinModelPortal:   P44630
- SMR:   P44630
- GeneID:   949437
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0309
- NMPDR:   fig|71421.1.peg.291
- TIGR:   HI_0309
- HOGENOM:   HBG727654
- OMA:   NEYWIEK
- ProtClustDB:   PRK00283
- BioCyc:   HINF71421:HI_0309-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02225

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34121; Mature: 34121

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: ACT_SITE 147-147 ACT_SITE 171-171 ACT_SITE 243-243 ACT_SITE 246-246 ACT_SITE 269-269 ACT_SITE 278-278

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVDLQGFLGE
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RLEKGYKATSTARMLSAMRKLFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LNTPNVEVPLELRDKAMLELLYATGLRVTELVSLTIENMSVQQGVVRVIGKGNKERIVPM
HCCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMTRQTFWHRVKHYAILADIDADAL
CHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHC
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNLALIDLFLNEYWIEKGLSENTVQSYRLDLTALCDWLDKNDLSLETLDAVDLQGFLGE
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RLEKGYKATSTARMLSAMRKLFQYLYREKYRVDDPSAVLSSPKLPSRLPKYLTEQQVSDL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LNTPNVEVPLELRDKAMLELLYATGLRVTELVSLTIENMSVQQGVVRVIGKGNKERIVPM
HCCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEEAAYWVRQFMLYGRPVLLNGQSSDVVFPSQRAQQMTRQTFWHRVKHYAILADIDADAL
CHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCHHHC
SPHVLRHAFATHLVNHGADLRVVQMLLGHTDLSTTQIYTHVAKERLKRLHERFHPRG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800