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The map label for this gene is hsdS

Identifier: 16272178

GI number: 16272178

Start: 233477

End: 234634

Strand: Direct

Name: hsdS

Synonym: HI0216

Alternate gene names: NA

Gene position: 233477-234634 (Clockwise)

Preceding gene: 30995361

Following gene: 16272179

Centisome position: 12.76

GC content: 34.8

Gene sequence:

>1158_bases
ATGAAAAACAACCGCACTTTTTTAGAAAAATTATTGGAGGGGTCTGAGGTTGAGTGGAAGCCTTTAGATGAAGTTGCCAA
TATCGTCAATAATGCAAGAAAACCAGTCAAATCATCCTTACGAGTGTCAGGGAATATTCCATATTATGGTGCTAATAATA
TCCAAGATTATGTCGAAGGATATACTCACGAGGGCGAATTTGTATTAATTGCTGAAGATGGTTCTGCTAGTCTAGAAAAT
TACTCTATTCAATGGGCTGTAGGTAAATTTTGGGCAAATAACCACGTCCATGTAGTAAATGGCAAAGAAAAATTAAATAA
TCGTTTTTTATACCATTATTTAACTAATATGAATTTCATTCCATTCTTAGCTGGAAAGGAACGTGCAAAATTAACAAAAG
CTAAACTGCAACAAATTCCAATCCCCATCCCCCCACTCTCCGTCCAAACCGAAATCGTAAAAATTTTGGACGCATTGACA
GCACTTACCAGCGAGCTTACCAGCGAGCTTACCAGCGAGCTTACCAGCGAGCTTATACTACGCCAGAAACAGTATGAATA
CTATCGAGAAAAATTGTTAAATATTGATGAAATGAACAAGGTTATTGAACTTGGTGATGTAGGGCCTGTTCGTATGTGTA
AACGAATTCTTAAAAACCAAACAGCAAGCTCTGGAGATATTCCATTTTATAAGATTGGAACTTTTGGGAAAAAGCCTGAT
GCCTATATTTCAAATGAGCTTTTCCAAGAATATAAACAAAAATATAGCTATCCTAAAAAAGGAGATATTCTTATATCTGC
TAGCGGAACTATTGGTAGAACAGTTATATTTGATGGAGAAAATTCTTATTTTCAAGATAGCAATATCGTCTGGATTGATA
ATGATGAAACTCTCGTTCTTAATAAATATTTATATCATTTCTATAAGATTGCTAAATGGGGAATTGCAGAAGGAGGCACC
ATTCAACGTTTATATAACGACAATTTGAAAAAAGTAAAAATTTCTATTCCTCCATTAAAGGAACAACACCGCATCGTTTC
AATCCTAGATAAATTTGAAACCTTAACCAATTCCATCACTGAAGGCTTACCTTTAGCGATTGAACAAAGCCAAAAGCGGT
ATGAATATTACCGAGAATTGCTATTAAATTTCTCGTAA

Upstream 100 bases:

>100_bases
CAGAAATTGAAGGGTAAAATGTAGGGTGGGCTTCAGCCCANTTTTACGATAACAGGTAGTGGGCTAAAGCCCACCCTACG
AGGAACAATAAAAAAACACC

Downstream 100 bases:

>100_bases
CCCGTAGTGGGCTTCAGCCCACCAATTAACCATAACAAACGGTGGGTTAAAGCTCACCCTACAATGTAATGAGAATATTT
TTATGGTGGGCTAAAGCCCA

Product: type I restriction/modification specificity protein

Products: NA

Alternate protein names: S protein

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKNNRTFLEKLLEGSEVEWKPLDEVANIVNNARKPVKSSLRVSGNIPYYGANNIQDYVEGYTHEGEFVLIAEDGSASLEN
YSIQWAVGKFWANNHVHVVNGKEKLNNRFLYHYLTNMNFIPFLAGKERAKLTKAKLQQIPIPIPPLSVQTEIVKILDALT
ALTSELTSELTSELTSELILRQKQYEYYREKLLNIDEMNKVIELGDVGPVRMCKRILKNQTASSGDIPFYKIGTFGKKPD
AYISNELFQEYKQKYSYPKKGDILISASGTIGRTVIFDGENSYFQDSNIVWIDNDETLVLNKYLYHFYKIAKWGIAEGGT
IQRLYNDNLKKVKISIPPLKEQHRIVSILDKFETLTNSITEGLPLAIEQSQKRYEYYRELLLNFS

Sequences:

>Translated_385_residues
MKNNRTFLEKLLEGSEVEWKPLDEVANIVNNARKPVKSSLRVSGNIPYYGANNIQDYVEGYTHEGEFVLIAEDGSASLEN
YSIQWAVGKFWANNHVHVVNGKEKLNNRFLYHYLTNMNFIPFLAGKERAKLTKAKLQQIPIPIPPLSVQTEIVKILDALT
ALTSELTSELTSELTSELILRQKQYEYYREKLLNIDEMNKVIELGDVGPVRMCKRILKNQTASSGDIPFYKIGTFGKKPD
AYISNELFQEYKQKYSYPKKGDILISASGTIGRTVIFDGENSYFQDSNIVWIDNDETLVLNKYLYHFYKIAKWGIAEGGT
IQRLYNDNLKKVKISIPPLKEQHRIVSILDKFETLTNSITEGLPLAIEQSQKRYEYYRELLLNFS
>Mature_385_residues
MKNNRTFLEKLLEGSEVEWKPLDEVANIVNNARKPVKSSLRVSGNIPYYGANNIQDYVEGYTHEGEFVLIAEDGSASLEN
YSIQWAVGKFWANNHVHVVNGKEKLNNRFLYHYLTNMNFIPFLAGKERAKLTKAKLQQIPIPIPPLSVQTEIVKILDALT
ALTSELTSELTSELTSELILRQKQYEYYREKLLNIDEMNKVIELGDVGPVRMCKRILKNQTASSGDIPFYKIGTFGKKPD
AYISNELFQEYKQKYSYPKKGDILISASGTIGRTVIFDGENSYFQDSNIVWIDNDETLVLNKYLYHFYKIAKWGIAEGGT
IQRLYNDNLKKVKISIPPLKEQHRIVSILDKFETLTNSITEGLPLAIEQSQKRYEYYRELLLNFS

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): T1SI_HAEIN (P71344)

Other databases:

- EMBL:   L42023
- PIR:   E64055
- RefSeq:   NP_438384.1
- ProteinModelPortal:   P71344
- REBASE:   6051
- GeneID:   951125
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0216
- NMPDR:   fig|71421.1.peg.204
- TIGR:   HI_0216
- HOGENOM:   HBG501841
- OMA:   LENYSIQ
- ProtClustDB:   CLSK808390
- BioCyc:   HINF71421:HI_0216-MONOMER
- InterPro:   IPR000055

Pfam domain/function: PF01420 Methylase_S

EC number: NA

Molecular weight: Translated: 44278; Mature: 44278

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNRTFLEKLLEGSEVEWKPLDEVANIVNNARKPVKSSLRVSGNIPYYGANNIQDYVEG
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCHHHHHCC
YTHEGEFVLIAEDGSASLENYSIQWAVGKFWANNHVHVVNGKEKLNNRFLYHYLTNMNFI
CCCCCCEEEEECCCCCCCCCEEEEEEEEEEECCCEEEEECCHHHHCCCEEEEHHCCCCCE
PFLAGKERAKLTKAKLQQIPIPIPPLSVQTEIVKILDALTALTSELTSELTSELTSELIL
EEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQKQYEYYREKLLNIDEMNKVIELGDVGPVRMCKRILKNQTASSGDIPFYKIGTFGKKPD
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
AYISNELFQEYKQKYSYPKKGDILISASGTIGRTVIFDGENSYFQDSNIVWIDNDETLVL
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCEECCCCEEEECCCCEEEH
NKYLYHFYKIAKWGIAEGGTIQRLYNDNLKKVKISIPPLKEQHRIVSILDKFETLTNSIT
HHHHHHHHHHHHCCCCCCCEEHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
EGLPLAIEQSQKRYEYYRELLLNFS
CCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNNRTFLEKLLEGSEVEWKPLDEVANIVNNARKPVKSSLRVSGNIPYYGANNIQDYVEG
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCCCCCCCCCHHHHHCC
YTHEGEFVLIAEDGSASLENYSIQWAVGKFWANNHVHVVNGKEKLNNRFLYHYLTNMNFI
CCCCCCEEEEECCCCCCCCCEEEEEEEEEEECCCEEEEECCHHHHCCCEEEEHHCCCCCE
PFLAGKERAKLTKAKLQQIPIPIPPLSVQTEIVKILDALTALTSELTSELTSELTSELIL
EEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQKQYEYYREKLLNIDEMNKVIELGDVGPVRMCKRILKNQTASSGDIPFYKIGTFGKKPD
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCC
AYISNELFQEYKQKYSYPKKGDILISASGTIGRTVIFDGENSYFQDSNIVWIDNDETLVL
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCCCEECCCCEEEECCCCEEEH
NKYLYHFYKIAKWGIAEGGTIQRLYNDNLKKVKISIPPLKEQHRIVSILDKFETLTNSIT
HHHHHHHHHHHHCCCCCCCEEHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
EGLPLAIEQSQKRYEYYRELLLNFS
CCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800