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The map label for this gene is yaaJ [C]

Identifier: 16272148

GI number: 16272148

Start: 197006

End: 198451

Strand: Direct

Name: yaaJ [C]

Synonym: HI0183

Alternate gene names: 16272148

Gene position: 197006-198451 (Clockwise)

Preceding gene: 30995357

Following gene: 16272151

Centisome position: 10.76

GC content: 40.8

Gene sequence:

>1446_bases
ATGATTATGGAATTTGAATTTTCAAAAATGTTAGAAGAAGTGCTAACTTGGATAGTCGCACACCTTGATGGACCTTTATG
GGATGCCACCATTATTATTTTGCTTGGGACTGGTCTATTTTTTACCATTACAACAGGATTTGTGCAGTTCCGTTTATTCC
CAGCAAGCCTTCGTGAAATGTGGTTTGGTCGTTCGGTGGAGGGGAGTTCATTAACACCTTTCCAAGCGTTTACAACAGGT
CTTGCGAGCCGCGTTGGTGTGGGTAACATTGGTGGGGTTGCAACGGCAATCGCCTTAGGGGGCGAAGGCGCAGTGTTTTG
GATGTGGGTAACGGCATTTATTGGTATGTCGAGTGCTTTCGCTGAATCTACCCTTGCTCAATTATTTAAAATTCAAGATA
AAGATGGATCATTCCGTGGCGGCCCTGCTTATTATATTGTGCAAGGTTTAAAATCACGTTGTATGGCAGTGGCTTTTGCG
CTTGCATTAATTTTTACATTTGGTTTTGCCTTTAATTCTGTGCAGGCAAACTCTATTGTTGAAGCAACCAGCAATGCGTG
GAATTGGAAAGGGGAATATGTCGGTATTTCATTAGTAATTTTTACCGCACTTATTATTTTCGGTGGCGTTAAGCGTATTG
CGATTATTTCGAGCAACCTTGTACCAATGATGGCACTTTTCTATTTGATTATGGCGGTAATTATTCTTGGCATGCATATT
GATATGATCCCTTCCGTGATTCATCGTATTGTTCAAAGTGCATTTAGTTTTGATGCTGCCGCTGGCGGAATGTTTGGTGC
ATTGGTATCGAAAGCAATGATGATGGGGATTAAACGTGGTTTATTCTCAAACGAAGCAGGGATGGGATCTGCGCCTAATT
CGGCTGCAGCAGCTCACGTTAAGCATCCAGTTAGCCAAGGTTTAGTGCAAATGCTCGGGGTGTTTGTTGATACAATGATC
GTTTGTACTTGTACTGCCGTTATTATTTTGCTTTCGAATAATTATGGTAGCGAAACGCTCAAAAGTATCTCTCTTACGCA
AAATGCTTTGCAATACCACATAGGTGAATTTGGGGCGCATTTCCTGGCGTTTATCTTATTGTTATTCGCTTATTCTTCTA
TTATTGGTAACTATGCTTATGCGGAAAGCAACATCCGTTTTATCAAGAATAAACCTTGGTTGGTCTTGTTGTTCCGTTTA
ATGGTGCTATTTTTCGTGTATTTCGGTGCGGTTCGCTCTGGTAATGTGGTGTGGAATTTCGCAGATACGGTGATGGCTGT
CATGGCAATCATTAACTTGATCGCAATTTTGATGTTGTCGCCAATCGTATGGAAATTAATGAAAGATTATCAACGCCAGC
TTAAAGAAGGAAAAACGCCAGAGTTTAAAATTGATGAATACCCTGAATTACGTAAGAAAATATTTGATTCCCGCATTTGG
AAATAA

Upstream 100 bases:

>100_bases
AGATTTTTTCTTGTTTGTGTTTCTTTCTTTAGAGAAATTATTAAAAAATCTCGCCTTTTCATTGAAAAGCCATACAATCA
AATTATTTATCGCTTGAGGG

Downstream 100 bases:

>100_bases
AGATAAAATGGCTAGAAAGAGATTATCTACCTTTCCAAAAAGAGTTAGATTATTATTTAAAGAAATTTTTTGATATTGTT
TCAGGCTTGGTTCTTCTAGT

Product: amino acid carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MIMEFEFSKMLEEVLTWIVAHLDGPLWDATIIILLGTGLFFTITTGFVQFRLFPASLREMWFGRSVEGSSLTPFQAFTTG
LASRVGVGNIGGVATAIALGGEGAVFWMWVTAFIGMSSAFAESTLAQLFKIQDKDGSFRGGPAYYIVQGLKSRCMAVAFA
LALIFTFGFAFNSVQANSIVEATSNAWNWKGEYVGISLVIFTALIIFGGVKRIAIISSNLVPMMALFYLIMAVIILGMHI
DMIPSVIHRIVQSAFSFDAAAGGMFGALVSKAMMMGIKRGLFSNEAGMGSAPNSAAAAHVKHPVSQGLVQMLGVFVDTMI
VCTCTAVIILLSNNYGSETLKSISLTQNALQYHIGEFGAHFLAFILLLFAYSSIIGNYAYAESNIRFIKNKPWLVLLFRL
MVLFFVYFGAVRSGNVVWNFADTVMAVMAIINLIAILMLSPIVWKLMKDYQRQLKEGKTPEFKIDEYPELRKKIFDSRIW
K

Sequences:

>Translated_481_residues
MIMEFEFSKMLEEVLTWIVAHLDGPLWDATIIILLGTGLFFTITTGFVQFRLFPASLREMWFGRSVEGSSLTPFQAFTTG
LASRVGVGNIGGVATAIALGGEGAVFWMWVTAFIGMSSAFAESTLAQLFKIQDKDGSFRGGPAYYIVQGLKSRCMAVAFA
LALIFTFGFAFNSVQANSIVEATSNAWNWKGEYVGISLVIFTALIIFGGVKRIAIISSNLVPMMALFYLIMAVIILGMHI
DMIPSVIHRIVQSAFSFDAAAGGMFGALVSKAMMMGIKRGLFSNEAGMGSAPNSAAAAHVKHPVSQGLVQMLGVFVDTMI
VCTCTAVIILLSNNYGSETLKSISLTQNALQYHIGEFGAHFLAFILLLFAYSSIIGNYAYAESNIRFIKNKPWLVLLFRL
MVLFFVYFGAVRSGNVVWNFADTVMAVMAIINLIAILMLSPIVWKLMKDYQRQLKEGKTPEFKIDEYPELRKKIFDSRIW
K
>Mature_481_residues
MIMEFEFSKMLEEVLTWIVAHLDGPLWDATIIILLGTGLFFTITTGFVQFRLFPASLREMWFGRSVEGSSLTPFQAFTTG
LASRVGVGNIGGVATAIALGGEGAVFWMWVTAFIGMSSAFAESTLAQLFKIQDKDGSFRGGPAYYIVQGLKSRCMAVAFA
LALIFTFGFAFNSVQANSIVEATSNAWNWKGEYVGISLVIFTALIIFGGVKRIAIISSNLVPMMALFYLIMAVIILGMHI
DMIPSVIHRIVQSAFSFDAAAGGMFGALVSKAMMMGIKRGLFSNEAGMGSAPNSAAAAHVKHPVSQGLVQMLGVFVDTMI
VCTCTAVIILLSNNYGSETLKSISLTQNALQYHIGEFGAHFLAFILLLFAYSSIIGNYAYAESNIRFIKNKPWLVLLFRL
MVLFFVYFGAVRSGNVVWNFADTVMAVMAIINLIAILMLSPIVWKLMKDYQRQLKEGKTPEFKIDEYPELRKKIFDSRIW
K

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family

Homologues:

Organism=Escherichia coli, GI1786188, Length=460, Percent_Identity=44.1304347826087, Blast_Score=353, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y183_HAEIN (P44555)

Other databases:

- EMBL:   L42023
- PIR:   I64144
- RefSeq:   NP_438351.1
- GeneID:   951094
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0183
- NMPDR:   fig|71421.1.peg.172
- TIGR:   HI_0183
- HOGENOM:   HBG671706
- OMA:   GLQNTEC
- ProtClustDB:   CLSK870148
- BioCyc:   HINF71421:HI_0183-MONOMER
- InterPro:   IPR001463
- PRINTS:   PR00175
- TIGRFAMs:   TIGR00835

Pfam domain/function: PF01235 Na_Ala_symp

EC number: NA

Molecular weight: Translated: 52954; Mature: 52954

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x94714a4)-; HASH(0xbb64b18)-; HASH(0x405be134)-; HASH(0xc3ab40c)-; HASH(0xc298bd0)-; HASH(0xc467750)-; HASH(0xc2a22a8)-; HASH(0xc2a813c)-; HASH(0xc2a217c)-; HASH(0xc192da4)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMEFEFSKMLEEVLTWIVAHLDGPLWDATIIILLGTGLFFTITTGFVQFRLFPASLREM
CCEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHH
WFGRSVEGSSLTPFQAFTTGLASRVGVGNIGGVATAIALGGEGAVFWMWVTAFIGMSSAF
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
AESTLAQLFKIQDKDGSFRGGPAYYIVQGLKSRCMAVAFALALIFTFGFAFNSVQANSIV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EATSNAWNWKGEYVGISLVIFTALIIFGGVKRIAIISSNLVPMMALFYLIMAVIILGMHI
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DMIPSVIHRIVQSAFSFDAAAGGMFGALVSKAMMMGIKRGLFSNEAGMGSAPNSAAAAHV
HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
KHPVSQGLVQMLGVFVDTMIVCTCTAVIILLSNNYGSETLKSISLTQNALQYHIGEFGAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLAFILLLFAYSSIIGNYAYAESNIRFIKNKPWLVLLFRLMVLFFVYFGAVRSGNVVWNF
HHHHHHHHHHHHHHHCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEH
ADTVMAVMAIINLIAILMLSPIVWKLMKDYQRQLKEGKTPEFKIDEYPELRKKIFDSRIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC
K
H
>Mature Secondary Structure
MIMEFEFSKMLEEVLTWIVAHLDGPLWDATIIILLGTGLFFTITTGFVQFRLFPASLREM
CCEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHH
WFGRSVEGSSLTPFQAFTTGLASRVGVGNIGGVATAIALGGEGAVFWMWVTAFIGMSSAF
HCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
AESTLAQLFKIQDKDGSFRGGPAYYIVQGLKSRCMAVAFALALIFTFGFAFNSVQANSIV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EATSNAWNWKGEYVGISLVIFTALIIFGGVKRIAIISSNLVPMMALFYLIMAVIILGMHI
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DMIPSVIHRIVQSAFSFDAAAGGMFGALVSKAMMMGIKRGLFSNEAGMGSAPNSAAAAHV
HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
KHPVSQGLVQMLGVFVDTMIVCTCTAVIILLSNNYGSETLKSISLTQNALQYHIGEFGAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLAFILLLFAYSSIIGNYAYAESNIRFIKNKPWLVLLFRLMVLFFVYFGAVRSGNVVWNF
HHHHHHHHHHHHHHHCCHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEH
ADTVMAVMAIINLIAILMLSPIVWKLMKDYQRQLKEGKTPEFKIDEYPELRKKIFDSRIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCC
K
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800