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The map label for this gene is siaP [H]

Identifier: 16272113

GI number: 16272113

Start: 161558

End: 162547

Strand: Direct

Name: siaP [H]

Synonym: HI0146

Alternate gene names: 16272113

Gene position: 161558-162547 (Clockwise)

Preceding gene: 16272106

Following gene: 16272114

Centisome position: 8.83

GC content: 36.57

Gene sequence:

>990_bases
ATGATGAAATTGACAAAACTTTTCCTTGCCACCGCCATTTCTTTAGGCGTATCTTCTGCTGTTCTTGCCGCTGATTATGA
CTTGAAATTCGGTATGAATGCTGGAACTTCATCAAATGAATATAAAGCGGCAGAAATGTTTGCCAAAGAAGTCAAAGAAA
AATCACAGGGTAAAATTGAAATTTCACTTTATCCAAGTTCACAATTAGGTGATGACCGTGCAATGTTAAAACAATTAAAA
GACGGTTCTCTCGACTTTACCTTTGCAGAATCTGCTCGCTTCCAGCTGTTTTACCCTGAAGCGGCAGTATTTGCCTTACC
TTATGTTATTAGCAACTACAATGTTGCACAAAAAGCCTTATTCGATACAGAATTCGGTAAAGATTTAATTAAAAAAATGG
ATAAAGATCTTGGCGTGACTTTACTTTCCCAAGCTTATAACGGAACTCGCCAAACGACTTCAAATCGTGCAATCAACAGT
ATTGCAGATATGAAAGGCTTAAAACTTCGTGTGCCAAATGCAGCAACAAACTTAGCCTATGCTAAATATGTTGGTGCATC
ACCAACACCAATGGCATTTTCTGAAGTTTATCTTGCGTTACAAACCAATGCCGTCGATGGTCAAGAAAACCCGTTAGCAG
CGGTGCAAGCACAAAAATTCTATGAAGTGCAAAAGTTCTTAGCAATGACTAATCATATTTTGAATGACCAACTTTATTTA
GTAAGCAACGAGACTTATAAAGAACTCCCTGAAGATCTTCAAAAAGTCGTAAAAGATGCTGCCGAAAATGCAGCAAAATA
TCACACTAAATTATTCGTAGATGGAGAGAAAGATTTAGTCACATTCTTTGAAAAACAAGGCGTGAAAATTACACATCCTG
ATCTTGTTCCATTTAAAGAATCAATGAAGCCGTATTATGCTGAGTTTGTAAAACAAACTGGTCAAAAAGGTGAATCAGCT
TTAAAACAAATTGAAGCAATCAATCCATAA

Upstream 100 bases:

>100_bases
TATTTTGGGGGAGAAAACATACATTTTTGGCCTAAATTGATTCTCATATTACGGGGTTAATCTATGCCCCTTTCCAACAT
AAGTTCACACAGGAGCGAAT

Downstream 100 bases:

>100_bases
TCCCTCTTTAGTGTGCCGTAATGGCCCTACATTCCCTTATTCTTCATCAAACGGAGTGAGTATGAAATATATTAATAAGC
TTGAGGAATGGCTGGGTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MMKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLK
DGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINS
IADMKGLKLRVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYL
VSNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESA
LKQIEAINP

Sequences:

>Translated_329_residues
MMKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLK
DGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINS
IADMKGLKLRVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYL
VSNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESA
LKQIEAINP
>Mature_329_residues
MMKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIEISLYPSSQLGDDRAMLKQLK
DGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKALFDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINS
IADMKGLKLRVPNAATNLAYAKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYL
VSNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKESMKPYYAEFVKQTGQKGESA
LKQIEAINP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=324, Percent_Identity=31.4814814814815, Blast_Score=164, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36513; Mature: 36513

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIE
CCHHHHHHHHHHHHHCHHHHHEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
ISLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKAL
EEECCCCCCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHCCCCHHHHHH
FDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLRVPNAATNLAY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHCCCCEEECCCCHHHHHH
AKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYL
HHHCCCCCCCHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VSNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKE
EECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCEEECCCCCCCHH
SMKPYYAEFVKQTGQKGESALKQIEAINP
HCCHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MMKLTKLFLATAISLGVSSAVLAADYDLKFGMNAGTSSNEYKAAEMFAKEVKEKSQGKIE
CCHHHHHHHHHHHHHCHHHHHEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCEEE
ISLYPSSQLGDDRAMLKQLKDGSLDFTFAESARFQLFYPEAAVFALPYVISNYNVAQKAL
EEECCCCCCCCHHHHHHHHCCCCCEEEEECCCEEEEECCCHHHHHHHHHHCCCCHHHHHH
FDTEFGKDLIKKMDKDLGVTLLSQAYNGTRQTTSNRAINSIADMKGLKLRVPNAATNLAY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCHHHHHHHHHHHCCCCEEECCCCHHHHHH
AKYVGASPTPMAFSEVYLALQTNAVDGQENPLAAVQAQKFYEVQKFLAMTNHILNDQLYL
HHHCCCCCCCHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VSNETYKELPEDLQKVVKDAAENAAKYHTKLFVDGEKDLVTFFEKQGVKITHPDLVPFKE
EECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCEEECCCCCCCHH
SMKPYYAEFVKQTGQKGESALKQIEAINP
HCCHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA