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The map label for this gene is bphH

Identifier: 16272085

GI number: 16272085

Start: 119451

End: 120080

Strand: Direct

Name: bphH

Synonym: HI0111

Alternate gene names: 16272085

Gene position: 119451-120080 (Clockwise)

Preceding gene: 16272084

Following gene: 16272087

Centisome position: 6.53

GC content: 36.51

Gene sequence:

>630_bases
ATGAAATTATATGGTTTAATTGGTGCGTGTTCATTTGTTCCACATGTGGCATTAGAGTGGGTAAAAATACGTGAAAATGC
TGATTATGAATTTGAACCTGTCACTCGTGAGTTAATTAAATCACCTGAATTTTTATCATTGAATCCACGCGGGGCAGTAC
CTGTATTAGTTGATGGCGATTTAGTTCTTTCGCAGAACCAAGCGATTTTGCACTATTTAGATGAACTTTATCCTAATTCA
AAATTATTTGGTAGCAAAACCGTACGTGATAAAGCCAAAGCAGCTCGCTGGTTAGCATTTTTTAATTCCGATGTGCATAA
ATCATTTGTGCCTCTGTTCCGTTTGCCAAACTATGCAAAAGATAACGAAACACTTGCACACACTATTCGCCAACAAGCAG
TAGAGCAAATTTTAGATCAACTTGCAGTCGCAAATGAGCATTTAGAAAGTCACATTTATTTTGGAGAAAATATTTCCGTT
GCAGATGCCTATCTTTACATTATGCTAAACTGGTGCAAAGCAGTCAAAATTGATTTCAGCCACTTAACACAACTTTCGGC
TTTTATGCAACGTGTTGAGACTGATCAAGCTGTCGAAAATGTGAGAAAAAGTGAAGAACTAAAAGTATAA

Upstream 100 bases:

>100_bases
ACGATTAAACAATAGTAAGAAGCAATTTTAATAAGTTAGATATTCCACGTATAAAACAGTATAATTCCATCAATAGCTCA
TAAACCAACAGGAGTATTTT

Downstream 100 bases:

>100_bases
ACAGGAAGTTTCTACAAAAATTGCCCGTTTTTAACCGTTTGTATCACGTTAAGTTTAAATTTAAGTGAGTAATTTCGCGT
CTTACCCAACACAGCTAACC

Product: glutathione transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGDLVLSQNQAILHYLDELYPNS
KLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAKDNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISV
ADAYLYIMLNWCKAVKIDFSHLTQLSAFMQRVETDQAVENVRKSEELKV

Sequences:

>Translated_209_residues
MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGDLVLSQNQAILHYLDELYPNS
KLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAKDNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISV
ADAYLYIMLNWCKAVKIDFSHLTQLSAFMQRVETDQAVENVRKSEELKV
>Mature_209_residues
MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGDLVLSQNQAILHYLDELYPNS
KLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAKDNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISV
ADAYLYIMLNWCKAVKIDFSHLTQLSAFMQRVETDQAVENVRKSEELKV

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain

Homologues:

Organism=Escherichia coli, GI1787923, Length=215, Percent_Identity=32.5581395348837, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GST_HAEIN (P44521)

Other databases:

- EMBL:   L42023
- PIR:   A64049
- RefSeq:   NP_438285.1
- ProteinModelPortal:   P44521
- SMR:   P44521
- GeneID:   951011
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0111
- NMPDR:   fig|71421.1.peg.108
- TIGR:   HI_0111
- HOGENOM:   HBG753188
- OMA:   IRENADY
- ProtClustDB:   CLSK892357
- BioCyc:   HINF71421:HI_0111-MONOMER
- BRENDA:   2.5.1.18
- GO:   GO:0005737
- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:1.20.1050.10
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF00043 GST_C; PF02798 GST_N; SSF47616 GST_C_like; SSF52833 Thiordxn-like_fd

EC number: =2.5.1.18

Molecular weight: Translated: 23926; Mature: 23926

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50405 GST_CTER; PS50404 GST_NTER

Important sites: BINDING 10-10 BINDING 53-53 BINDING 106-106

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEECCC
LVLSQNQAILHYLDELYPNSKLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAK
EEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCC
DNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISVADAYLYIMLNWCKAVKIDFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
HLTQLSAFMQRVETDQAVENVRKSEELKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLYGLIGACSFVPHVALEWVKIRENADYEFEPVTRELIKSPEFLSLNPRGAVPVLVDGD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEECCC
LVLSQNQAILHYLDELYPNSKLFGSKTVRDKAKAARWLAFFNSDVHKSFVPLFRLPNYAK
EEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCC
DNETLAHTIRQQAVEQILDQLAVANEHLESHIYFGENISVADAYLYIMLNWCKAVKIDFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
HLTQLSAFMQRVETDQAVENVRKSEELKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800