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The map label for this gene is cysS [H]

Identifier: 16272052

GI number: 16272052

Start: 84580

End: 85959

Strand: Reverse

Name: cysS [H]

Synonym: HI0078

Alternate gene names: 16272052

Gene position: 85959-84580 (Counterclockwise)

Preceding gene: 16272058

Following gene: 16272048

Centisome position: 4.7

GC content: 40.29

Gene sequence:

>1380_bases
ATGCTAAAAATTTTCAATACCTTAACGAGAGAAAAAGAAATCTTTAAACCTATCCACGAAAATAAAGTGGGAATGTATGT
TTGCGGCGTCACTGTTTATGATTTGTGCCATATCGGCCATGGACGCACTTTTGTGTGTTTTGATGTGATTGCCCGTTATT
TACGTTCTTTGGGTTACGATTTAACTTATGTGCGTAATATAACGGACGTAGATGACAAAATTATTAAACGTGCGTTAGAA
AACAAAGAAACCTGCGATCAGTTAGTGGATCGCATGGTGCAGGAAATGTATAAAGATTTTGATGCACTTAATGTCTTACG
CCCTGATTTTGAACCTCGTGCGACGCATCATATTCCAGAAATTATTGAAATTGTGGAAAAATTAATTAAACGCGGACATG
CTTATGTTGCGGATAATGGGGACGTGATGTTTGATGTAGAAAGCTTCAAAGAATACGGCAAATTATCCCGTCAAGATCTT
GAGCAATTACAAGCTGGCGCACGTATTGAAATCAATGAAATCAAGAAAAATCCAATGGATTTCGTGCTTTGGAAAATGTC
GAAAGAAAACGAACCAAGTTGGGCTTCCCCTTGGGGGGCAGGTCGTCCGGGTTGGCATATTGAATGTTCTGCAATGAACT
GCAAACAGCTTGGCGAATATTTTGATATTCACGGTGGTGGCTCTGATTTAATGTTCCCTCACCACGAAAATGAAATTGCA
CAATCTTGCTGTGCGCATGGCGGCCAATATGTGAATTATTGGATCCATTCTGGCATGATTATGGTGGATAAAGAAAAAAT
GTCGAAATCCCTCGGCAATTTCTTCACAATTCGTGATGTATTAAACCACTACAATGCAGAAGCGGTGCGTTATTTCTTAT
TAACGGCACATTATCGTAGCCAGCTCAATTATAGCGAAGAAAACTTGAATTTAGCACAAGGTGCGTTGGAACGTTTATAC
ACGGCTTTACGCGGAACAGATCAAAGTGCGGTTGCTTTTGGCGGAGAAAATTTTGTTGCAACTTTCCGTGAAGCAATGGA
TGATGATTTTAATACGCCAAATGCACTTTCTGTTTTATTCGAAATGGCACGTGAAATTAATAAGTTAAAAACAGAAGATG
TTGAGAAAGCTAATGGACTTGCTGCACGTTTGCGTGAATTGGGGGCGATTTTAGGATTACTTCAACAAGAACCAGAGAAA
TTCTTACAAGCAGGTTCTAACGATGATGAAGTGGCAAAAATTGAGGCACTCATCAAACAACGCAACGAAGCCCGCACTGC
TAAAGATTGGTCTGCCGCAGATTCAGCACGTAATGAATTGACAGCTATGGGCATCGTATTAGAAGATGGGCCGAATGGGA
CAACTTGGCGTAAGCAATAA

Upstream 100 bases:

>100_bases
TGTTTTCCCTCTAAAAAATTAAGGGTTGTATTATTCCACAATCGAGGTAAAAGTGCTATAAAAGTGCGGTTTGTTTTTAT
TTCATTTTACGAGCTTAAAA

Downstream 100 bases:

>100_bases
ATTCAAACGTTAAATCACTTTCATTAAAAGGACTAAGTTCGGTATTCAATCGAACTTAGTCTCTTTATTTTTTCATCATT
TCTTAATATAGGATTTTAAT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MLKIFNTLTREKEIFKPIHENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRSLGYDLTYVRNITDVDDKIIKRALE
NKETCDQLVDRMVQEMYKDFDALNVLRPDFEPRATHHIPEIIEIVEKLIKRGHAYVADNGDVMFDVESFKEYGKLSRQDL
EQLQAGARIEINEIKKNPMDFVLWKMSKENEPSWASPWGAGRPGWHIECSAMNCKQLGEYFDIHGGGSDLMFPHHENEIA
QSCCAHGGQYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYNAEAVRYFLLTAHYRSQLNYSEENLNLAQGALERLY
TALRGTDQSAVAFGGENFVATFREAMDDDFNTPNALSVLFEMAREINKLKTEDVEKANGLAARLRELGAILGLLQQEPEK
FLQAGSNDDEVAKIEALIKQRNEARTAKDWSAADSARNELTAMGIVLEDGPNGTTWRKQ

Sequences:

>Translated_459_residues
MLKIFNTLTREKEIFKPIHENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRSLGYDLTYVRNITDVDDKIIKRALE
NKETCDQLVDRMVQEMYKDFDALNVLRPDFEPRATHHIPEIIEIVEKLIKRGHAYVADNGDVMFDVESFKEYGKLSRQDL
EQLQAGARIEINEIKKNPMDFVLWKMSKENEPSWASPWGAGRPGWHIECSAMNCKQLGEYFDIHGGGSDLMFPHHENEIA
QSCCAHGGQYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYNAEAVRYFLLTAHYRSQLNYSEENLNLAQGALERLY
TALRGTDQSAVAFGGENFVATFREAMDDDFNTPNALSVLFEMAREINKLKTEDVEKANGLAARLRELGAILGLLQQEPEK
FLQAGSNDDEVAKIEALIKQRNEARTAKDWSAADSARNELTAMGIVLEDGPNGTTWRKQ
>Mature_459_residues
MLKIFNTLTREKEIFKPIHENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRSLGYDLTYVRNITDVDDKIIKRALE
NKETCDQLVDRMVQEMYKDFDALNVLRPDFEPRATHHIPEIIEIVEKLIKRGHAYVADNGDVMFDVESFKEYGKLSRQDL
EQLQAGARIEINEIKKNPMDFVLWKMSKENEPSWASPWGAGRPGWHIECSAMNCKQLGEYFDIHGGGSDLMFPHHENEIA
QSCCAHGGQYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYNAEAVRYFLLTAHYRSQLNYSEENLNLAQGALERLY
TALRGTDQSAVAFGGENFVATFREAMDDDFNTPNALSVLFEMAREINKLKTEDVEKANGLAARLRELGAILGLLQQEPEK
FLQAGSNDDEVAKIEALIKQRNEARTAKDWSAADSARNELTAMGIVLEDGPNGTTWRKQ

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=413, Percent_Identity=38.498789346247, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI62240992, Length=232, Percent_Identity=43.9655172413793, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI10835051, Length=232, Percent_Identity=43.9655172413793, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI21269877, Length=232, Percent_Identity=43.9655172413793, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI303304987, Length=232, Percent_Identity=43.9655172413793, Blast_Score=194, Evalue=2e-49,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=75.4880694143167, Blast_Score=728, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509795, Length=247, Percent_Identity=41.2955465587045, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17509797, Length=247, Percent_Identity=41.2955465587045, Blast_Score=183, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324082, Length=389, Percent_Identity=32.133676092545, Blast_Score=200, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19922218, Length=500, Percent_Identity=35, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI19922364, Length=233, Percent_Identity=42.4892703862661, Blast_Score=187, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52357; Mature: 52357

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIFNTLTREKEIFKPIHENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRSLGYD
CCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCC
LTYVRNITDVDDKIIKRALENKETCDQLVDRMVQEMYKDFDALNVLRPDFEPRATHHIPE
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCHHH
IIEIVEKLIKRGHAYVADNGDVMFDVESFKEYGKLSRQDLEQLQAGARIEINEIKKNPMD
HHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCHH
FVLWKMSKENEPSWASPWGAGRPGWHIECSAMNCKQLGEYFDIHGGGSDLMFPHHENEIA
EEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHEECCCCCCCCCCCCCHHHHH
QSCCAHGGQYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYNAEAVRYFLLTAHYRS
HHHHHCCCCEEEHHHHCCEEEEEHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
QLNYSEENLNLAQGALERLYTALRGTDQSAVAFGGENFVATFREAMDDDFNTPNALSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHH
EMAREINKLKTEDVEKANGLAARLRELGAILGLLQQEPEKFLQAGSNDDEVAKIEALIKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHH
RNEARTAKDWSAADSARNELTAMGIVLEDGPNGTTWRKQ
HHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLKIFNTLTREKEIFKPIHENKVGMYVCGVTVYDLCHIGHGRTFVCFDVIARYLRSLGYD
CCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCC
LTYVRNITDVDDKIIKRALENKETCDQLVDRMVQEMYKDFDALNVLRPDFEPRATHHIPE
EEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCHHH
IIEIVEKLIKRGHAYVADNGDVMFDVESFKEYGKLSRQDLEQLQAGARIEINEIKKNPMD
HHHHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCHH
FVLWKMSKENEPSWASPWGAGRPGWHIECSAMNCKQLGEYFDIHGGGSDLMFPHHENEIA
EEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHEECCCCCCCCCCCCCHHHHH
QSCCAHGGQYVNYWIHSGMIMVDKEKMSKSLGNFFTIRDVLNHYNAEAVRYFLLTAHYRS
HHHHHCCCCEEEHHHHCCEEEEEHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
QLNYSEENLNLAQGALERLYTALRGTDQSAVAFGGENFVATFREAMDDDFNTPNALSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHH
EMAREINKLKTEDVEKANGLAARLRELGAILGLLQQEPEKFLQAGSNDDEVAKIEALIKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHH
RNEARTAKDWSAADSARNELTAMGIVLEDGPNGTTWRKQ
HHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA