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The map label for this gene is fdxI

Identifier: 16271983

GI number: 16271983

Start: 9681

End: 10397

Strand: Direct

Name: fdxI

Synonym: HI0008

Alternate gene names: 16271983

Gene position: 9681-10397 (Clockwise)

Preceding gene: 16271982

Following gene: 16271984

Centisome position: 0.53

GC content: 38.49

Gene sequence:

>717_bases
ATGAGTAAAATTGAAATTAGCAACGATACTCGCATTATCCGCCATAGAACCCCAGCACGTATCAGTCACTGGATGTTGGT
TATTTGCTTTTTTATGACGATGTTCACTGGTGTTGCATTTTTCTTCCCTGACTTTGCTTGGCTCACAGAAATTTTGGGTA
CACCACAAATTGCGCGCGCCATTCATCCATTCACAGGGATTTTAATGTTCTTCGCTTTCATCTACTTAGCGTTATTGTAC
TGGGATCACAATATTCCAGAAAAAAACGATATTCGCTGGGCGAAAGGTGTTATTGAAGTTCTTAAAGGGAATGAACACGC
GGTTGCTGATAATGGCAAATATAACCTTGGTCAAAAAATGCTCTTTTGGACATTAAACTTGGCAATGGTAACGTTATTAG
TCACTGGCATCATTATGTGGCGTCAATATTTTTCACATTACTTCTCAATCCCAGTATTGCGAATTGCTATTTTACTCCAC
TCTGCAAGTGCTTTTATGTTATTCACTGGTATCTTAGTGCATATATATATGGCATTTTGGGTTAAAGGATCAATTCGCGG
TATTGTTGAAGGTTGGGTAACCGTTCGTTGGGCGAAAAAACACCACCCAAGATGGTATCGTGAAGAAGTTTTATCAAAAC
TTGAGGAAGATTTACTCAACGAGCAATCTGGCAAAGTAGGTAAAACCAAAGTCTTATTTAAAGGATTTGGCAAATAA

Upstream 100 bases:

>100_bases
GAAGTTGCGCACTACTTAACCGTTGGCCCAAATGTAGAAGAAGATGTGGAAGATCATCATCACGAATTTGAAGAAAATAA
ACCATCTAAGGGGGAAAATA

Downstream 100 bases:

>100_bases
GCTGAAATCCTGAAAAAGAAAAAGTGCGGTTAAAATTGACCGCACTTTTTATTATAAAAGTGAGAGAATATGAGTATCAA
AATCTTATCTGAATCAGAAA

Product: formate dehydrogenase subunit gamma

Products: CO2; NADH

Alternate protein names: Formate dehydrogenase subunit gamma; FDH subunit gamma

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVAFFFPDFAWLTEILGTPQIARAIHPFTGILMFFAFIYLALLY
WDHNIPEKNDIRWAKGVIEVLKGNEHAVADNGKYNLGQKMLFWTLNLAMVTLLVTGIIMWRQYFSHYFSIPVLRIAILLH
SASAFMLFTGILVHIYMAFWVKGSIRGIVEGWVTVRWAKKHHPRWYREEVLSKLEEDLLNEQSGKVGKTKVLFKGFGK

Sequences:

>Translated_238_residues
MSKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVAFFFPDFAWLTEILGTPQIARAIHPFTGILMFFAFIYLALLY
WDHNIPEKNDIRWAKGVIEVLKGNEHAVADNGKYNLGQKMLFWTLNLAMVTLLVTGIIMWRQYFSHYFSIPVLRIAILLH
SASAFMLFTGILVHIYMAFWVKGSIRGIVEGWVTVRWAKKHHPRWYREEVLSKLEEDLLNEQSGKVGKTKVLFKGFGK
>Mature_237_residues
SKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVAFFFPDFAWLTEILGTPQIARAIHPFTGILMFFAFIYLALLYW
DHNIPEKNDIRWAKGVIEVLKGNEHAVADNGKYNLGQKMLFWTLNLAMVTLLVTGIIMWRQYFSHYFSIPVLRIAILLHS
ASAFMLFTGILVHIYMAFWVKGSIRGIVEGWVTVRWAKKHHPRWYREEVLSKLEEDLLNEQSGKVGKTKVLFKGFGK

Specific function: Allows to use formate as major electron donor during anaerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase

COG id: COG2864

COG function: function code C; Cytochrome b subunit of formate dehydrogenase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formate dehydrogenase gamma subunit family

Homologues:

Organism=Escherichia coli, GI1787750, Length=218, Percent_Identity=50.9174311926605, Blast_Score=235, Evalue=1e-63,
Organism=Escherichia coli, GI1790325, Length=201, Percent_Identity=51.7412935323383, Blast_Score=227, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FDXI_HAEIN (P44451)

Other databases:

- EMBL:   L42023
- RefSeq:   NP_438181.1
- ProteinModelPortal:   P44451
- SMR:   P44451
- GeneID:   950906
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0008
- NMPDR:   fig|71421.1.peg.7
- TIGR:   HI_0008
- HOGENOM:   HBG488114
- OMA:   SGLAMFH
- ProtClustDB:   CLSK870083
- BioCyc:   HINF71421:HI_0008-MONOMER
- GO:   GO:0006810
- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR006471
- TIGRFAMs:   TIGR01583

Pfam domain/function: PF00033 Cytochrom_B_N; SSF81342 Transmembr_di-haem_cytochrome

EC number: 1.2.1.2

Molecular weight: Translated: 27758; Mature: 27627

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91fcc48)-; HASH(0xbb1c26c)-; HASH(0xbb01f68)-; HASH(0xbb175e8)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVAFFFPDFAWLTEILGTPQIARA
CCCEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHH
IHPFTGILMFFAFIYLALLYWDHNIPEKNDIRWAKGVIEVLKGNEHAVADNGKYNLGQKM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCHHH
LFWTLNLAMVTLLVTGIIMWRQYFSHYFSIPVLRIAILLHSASAFMLFTGILVHIYMAFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKGSIRGIVEGWVTVRWAKKHHPRWYREEVLSKLEEDLLNEQSGKVGKTKVLFKGFGK
HHHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCH
>Mature Secondary Structure 
SKIEISNDTRIIRHRTPARISHWMLVICFFMTMFTGVAFFFPDFAWLTEILGTPQIARA
CCEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHH
IHPFTGILMFFAFIYLALLYWDHNIPEKNDIRWAKGVIEVLKGNEHAVADNGKYNLGQKM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCHHH
LFWTLNLAMVTLLVTGIIMWRQYFSHYFSIPVLRIAILLHSASAFMLFTGILVHIYMAFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKGSIRGIVEGWVTVRWAKKHHPRWYREEVLSKLEEDLLNEQSGKVGKTKVLFKGFGK
HHHHHHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800