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The map label for this gene is xerD [H]

Identifier: 162447539

GI number: 162447539

Start: 713248

End: 714153

Strand: Direct

Name: xerD [H]

Synonym: ACL_0679

Alternate gene names: 162447539

Gene position: 713248-714153 (Clockwise)

Preceding gene: 162447538

Following gene: 162447540

Centisome position: 47.65

GC content: 29.91

Gene sequence:

>906_bases
ATGACCTATTTAATCAAAGATTTTTCTTATTATTTGAATAATGAATTGGGTTTATCCAAGAATACCATTGATGCATATAT
GAGAGATTTAAAGGACTATGAATCTTTCTTAGATAAATATCATAAATTAAAAGATGTAGATAACATTCAATCAAAGCACA
TTGAAGGTTATCTTAAAAGTATTAAGAAAAAGGGATTATCTGCTAAAACGATATCTAGAAAACTCACCTCAATTAAATCA
TTTCATAAGTTTTTACTGATGGAAAAAGAAGTGGATGAAGATGTTACGCATAAAATTGCTAGACCTAAAATAGAAAAAAC
TTTACCTACAGTATTAAGTGTAGATGAGGTAATTAGTATATTAGAAGTCATAGATAAGTCCACGACATTGGGTTTAAGAA
ATATGGCATTGCTAGAACTTATATACGGTTCTGGACTGCGTGTTTCTGAATTACTTAATATAAAATTAAAGGATATCCAT
ATGCAACAAAGCTATGTTATTGTCACTGGTAAAGGGTCAAAAGAACGTATGGTACCTATATCGGATATGGCAATTATAGC
AATTAGAAATTATTTAGTTAAGGCTAGAGATGATTTGATTAAGGAAAAAACAGATTATTTATTTATTAATAATCAAGGTA
AAACACTTTCACGTGTAGGCTTTTTTAAAGTCTTAAAAAAGCTTGCAAGCGAAGCAAATTTAGACCCTGAAAAAGTGTCA
CCACATACCTTAAGGCATTCATTTGCAACACACCTTTTAGAGAATGGAATGGATTTAAGAAGTCTTCAAAACCTACTTGG
CCATGAAGATATATCGACTACACAAATCTATACACACATCTCACAATCAAGATTAAAACAAGTTTATAACAAAACTCATC
CAAGAGCAAAGGAGAATAACAAATGA

Upstream 100 bases:

>100_bases
ATGATAAAATAAAACTAGGATTACTTGAAATTAAAGATGACTATATACGTCTAACTAAGGAAGGTACAATGCTTGGTAAT
CAAGTATTTATGATATTTGT

Downstream 100 bases:

>100_bases
GATTTAAAAGAGTATTTTTAATCGTCATGGACTCTTTAGGAGTCGGTGCATCAGAAGATGCAAATCAATATTTTAATGAA
GGGGTAGACGATACAAAAGC

Product: site-specific tyrosine recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTYLIKDFSYYLNNELGLSKNTIDAYMRDLKDYESFLDKYHKLKDVDNIQSKHIEGYLKSIKKKGLSAKTISRKLTSIKS
FHKFLLMEKEVDEDVTHKIARPKIEKTLPTVLSVDEVISILEVIDKSTTLGLRNMALLELIYGSGLRVSELLNIKLKDIH
MQQSYVIVTGKGSKERMVPISDMAIIAIRNYLVKARDDLIKEKTDYLFINNQGKTLSRVGFFKVLKKLASEANLDPEKVS
PHTLRHSFATHLLENGMDLRSLQNLLGHEDISTTQIYTHISQSRLKQVYNKTHPRAKENNK

Sequences:

>Translated_301_residues
MTYLIKDFSYYLNNELGLSKNTIDAYMRDLKDYESFLDKYHKLKDVDNIQSKHIEGYLKSIKKKGLSAKTISRKLTSIKS
FHKFLLMEKEVDEDVTHKIARPKIEKTLPTVLSVDEVISILEVIDKSTTLGLRNMALLELIYGSGLRVSELLNIKLKDIH
MQQSYVIVTGKGSKERMVPISDMAIIAIRNYLVKARDDLIKEKTDYLFINNQGKTLSRVGFFKVLKKLASEANLDPEKVS
PHTLRHSFATHLLENGMDLRSLQNLLGHEDISTTQIYTHISQSRLKQVYNKTHPRAKENNK
>Mature_300_residues
TYLIKDFSYYLNNELGLSKNTIDAYMRDLKDYESFLDKYHKLKDVDNIQSKHIEGYLKSIKKKGLSAKTISRKLTSIKSF
HKFLLMEKEVDEDVTHKIARPKIEKTLPTVLSVDEVISILEVIDKSTTLGLRNMALLELIYGSGLRVSELLNIKLKDIHM
QQSYVIVTGKGSKERMVPISDMAIIAIRNYLVKARDDLIKEKTDYLFINNQGKTLSRVGFFKVLKKLASEANLDPEKVSP
HTLRHSFATHLLENGMDLRSLQNLLGHEDISTTQIYTHISQSRLKQVYNKTHPRAKENNK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:
GO:0003677: Tyrosine recombinase xerC 1
GO:0005737: Tyrosine recombinase xerC 1
GO:0006310: Tyrosine recombinase xerC 1
GO:0006313: Tyrosine recombinase xerC 1
GO:0007049: Tyrosine recombinase xerC 1
GO:0007059: Tyrosine recombinase xerC 1
GO:0009037: Tyrosine recombinase xerC 1
GO:0015074: Tyrosine recombinase xerC 1
GO:0051301: Tyrosine recombinase xerC 1

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=38.9078498293515, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=35.2542372881356, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1790767, Length=188, Percent_Identity=26.063829787234, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=27.0718232044199, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34642; Mature: 34511

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLIKDFSYYLNNELGLSKNTIDAYMRDLKDYESFLDKYHKLKDVDNIQSKHIEGYLKS
CCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKKGLSAKTISRKLTSIKSFHKFLLMEKEVDEDVTHKIARPKIEKTLPTVLSVDEVISI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LEVIDKSTTLGLRNMALLELIYGSGLRVSELLNIKLKDIHMQQSYVIVTGKGSKERMVPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEECCCEEEEECCCCCCCCCCH
SDMAIIAIRNYLVKARDDLIKEKTDYLFINNQGKTLSRVGFFKVLKKLASEANLDPEKVS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCC
PHTLRHSFATHLLENGMDLRSLQNLLGHEDISTTQIYTHISQSRLKQVYNKTHPRAKENN
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
K
C
>Mature Secondary Structure 
TYLIKDFSYYLNNELGLSKNTIDAYMRDLKDYESFLDKYHKLKDVDNIQSKHIEGYLKS
CEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKKKGLSAKTISRKLTSIKSFHKFLLMEKEVDEDVTHKIARPKIEKTLPTVLSVDEVISI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LEVIDKSTTLGLRNMALLELIYGSGLRVSELLNIKLKDIHMQQSYVIVTGKGSKERMVPI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEECCCEEEEECCCCCCCCCCH
SDMAIIAIRNYLVKARDDLIKEKTDYLFINNQGKTLSRVGFFKVLKKLASEANLDPEKVS
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCC
PHTLRHSFATHLLENGMDLRSLQNLLGHEDISTTQIYTHISQSRLKQVYNKTHPRAKENN
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]