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The map label for this gene is hsdM1 [C]

Identifier: 162447450

GI number: 162447450

Start: 621423

End: 622910

Strand: Direct

Name: hsdM1 [C]

Synonym: ACL_0589

Alternate gene names: 162447450

Gene position: 621423-622910 (Clockwise)

Preceding gene: 162447449

Following gene: 162447451

Centisome position: 41.51

GC content: 34.41

Gene sequence:

>1488_bases
ATGGCTGATTTACAATTAGGATTCGAAGATAAGCTATGGCAAATGGCTGATAAGCTTAGAGGTAATATCGAATCATCAGA
ATATAAGCACGTGATATTAGGTCTTGTGTTCCTTAAATACATTTCAGATTCATTTACAGAACGTTATGAAGAAATAAAAG
CAAATTATCCAGGTATGGAAGAAGATAGAGATGCATATGAATCAGAAAATGTGTTTTTCGTACCTAAAGATGCTAGATGG
GAATATATCAAATCTCAAGCGAAACAATCAACCATCGGACAGATTATTGATAATGCAATGGTTCAAATAGAAAAAGAAAA
TGCATCACTAAAAGGTGTATTACCTAAAAACTATGCAAGACCAGAACTAGATAAGACTCGACTAGGTGAACTTATTGATC
TATTCTCATTTAATGTAGGGTCTAAAGAAGCAAGAGCAAAAGATGTACTTGGAAGAGTCTATGAGTATTTTCTTAAAAAG
TTTGGAACAACTGAAGGTGAATTCTATACACCACCAGCAATTGTAAAATTACTTGTAAACATGATTGAACCATATAACGG
TAGAGTTTATGACCCTTGTTGTGGTTCTGGAGGTATGTTTGTACAATCCGCTAAATTCGTTGAAGAACATGCTGGTAAAA
TTGGGAATATTTCTATCTATGGCCAAGAATATGTTGCAACCACATGGCGTTTAGCAAAGATGAATCTAGCTATTCGAGGA
ATTGATGCAAACCTTGGTGAAAGAGATGGGGATACTTTTACTAACGATCAACACAAAACATTAAGAGCTGATTATATCCT
TGCAAACCCACCATTTAACATTAAAGATTGGGGACAACAGCACTTAATCGGAGATAGTAGATGGCAATGGGGAACACCTC
CGGCGACTAATGCTAACTACGCTTGGATATCACATATGATTTCAAAACTAAGCCCAAGAGGTATTGCGGGTTTTGTTTTA
GCAAATGGATCATTATCTACTTCAAGAAGTGAAGAATATGAAATTAGAAAAAAGATACTTGAAGAAGGATTAGTTGATTG
TATCGTAGCAATGCCATCACAACTTTTCTATGATGTATCAATTCCAGTATCATTATGGTTTGTTTCAAAAAATAAAAATG
GTAGAAAAGATAAAGTCTTATTCATTGATGCTCGTAAGATGGGGTATATGGAAACCAGAAAGCATAGAGAACTTACTGAT
GAAGAAAGTGAGAAGATCTATTCAACCTACCATGCATGGAGAGATGATAAGGATTATCAAGATATTGATGGGTTCTGTAA
ATCTGCAACACTTGAAGAAATTAGATCACATGATTATGTTTTAACACCAGGTAGATATGTTGGTATAGAAGAAGTTGAAG
ATGATGGTATTCCATTTGAAGAAAAGATGGAAAAACTGACTTTAGAATTATCTGAGTTATTTGAAGAATCTAAATCTCTT
GAGGAAAAGATCAAAGAGAACTTAAGAGGTATCGGGTATGAGCTTTGA

Upstream 100 bases:

>100_bases
ACTGACACAAGATAGCCTTTAATTGCAATAAGATGTCGTTTTTTGCATATAAATAGTGTATAATATTTAAAATAGAACAT
TTAATGAATGGGGAGAAAAT

Downstream 100 bases:

>100_bases
TCAATGGAGTAAAGTCAATTTGGTGGATTGTCTCGACAAATTGATTGATTATAGAGGTAAAACACCAGCAAAATCAGAAA
AAGGGATATTAACGTTAAGT

Product: type I site-specific restriction-modification system, M (modification) subunit

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MADLQLGFEDKLWQMADKLRGNIESSEYKHVILGLVFLKYISDSFTERYEEIKANYPGMEEDRDAYESENVFFVPKDARW
EYIKSQAKQSTIGQIIDNAMVQIEKENASLKGVLPKNYARPELDKTRLGELIDLFSFNVGSKEARAKDVLGRVYEYFLKK
FGTTEGEFYTPPAIVKLLVNMIEPYNGRVYDPCCGSGGMFVQSAKFVEEHAGKIGNISIYGQEYVATTWRLAKMNLAIRG
IDANLGERDGDTFTNDQHKTLRADYILANPPFNIKDWGQQHLIGDSRWQWGTPPATNANYAWISHMISKLSPRGIAGFVL
ANGSLSTSRSEEYEIRKKILEEGLVDCIVAMPSQLFYDVSIPVSLWFVSKNKNGRKDKVLFIDARKMGYMETRKHRELTD
EESEKIYSTYHAWRDDKDYQDIDGFCKSATLEEIRSHDYVLTPGRYVGIEEVEDDGIPFEEKMEKLTLELSELFEESKSL
EEKIKENLRGIGYEL

Sequences:

>Translated_495_residues
MADLQLGFEDKLWQMADKLRGNIESSEYKHVILGLVFLKYISDSFTERYEEIKANYPGMEEDRDAYESENVFFVPKDARW
EYIKSQAKQSTIGQIIDNAMVQIEKENASLKGVLPKNYARPELDKTRLGELIDLFSFNVGSKEARAKDVLGRVYEYFLKK
FGTTEGEFYTPPAIVKLLVNMIEPYNGRVYDPCCGSGGMFVQSAKFVEEHAGKIGNISIYGQEYVATTWRLAKMNLAIRG
IDANLGERDGDTFTNDQHKTLRADYILANPPFNIKDWGQQHLIGDSRWQWGTPPATNANYAWISHMISKLSPRGIAGFVL
ANGSLSTSRSEEYEIRKKILEEGLVDCIVAMPSQLFYDVSIPVSLWFVSKNKNGRKDKVLFIDARKMGYMETRKHRELTD
EESEKIYSTYHAWRDDKDYQDIDGFCKSATLEEIRSHDYVLTPGRYVGIEEVEDDGIPFEEKMEKLTLELSELFEESKSL
EEKIKENLRGIGYEL
>Mature_494_residues
ADLQLGFEDKLWQMADKLRGNIESSEYKHVILGLVFLKYISDSFTERYEEIKANYPGMEEDRDAYESENVFFVPKDARWE
YIKSQAKQSTIGQIIDNAMVQIEKENASLKGVLPKNYARPELDKTRLGELIDLFSFNVGSKEARAKDVLGRVYEYFLKKF
GTTEGEFYTPPAIVKLLVNMIEPYNGRVYDPCCGSGGMFVQSAKFVEEHAGKIGNISIYGQEYVATTWRLAKMNLAIRGI
DANLGERDGDTFTNDQHKTLRADYILANPPFNIKDWGQQHLIGDSRWQWGTPPATNANYAWISHMISKLSPRGIAGFVLA
NGSLSTSRSEEYEIRKKILEEGLVDCIVAMPSQLFYDVSIPVSLWFVSKNKNGRKDKVLFIDARKMGYMETRKHRELTDE
ESEKIYSTYHAWRDDKDYQDIDGFCKSATLEEIRSHDYVLTPGRYVGIEEVEDDGIPFEEKMEKLTLELSELFEESKSLE
EKIKENLRGIGYEL

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=394, Percent_Identity=22.0812182741117, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 56834; Mature: 56703

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLQLGFEDKLWQMADKLRGNIESSEYKHVILGLVFLKYISDSFTERYEEIKANYPGME
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EDRDAYESENVFFVPKDARWEYIKSQAKQSTIGQIIDNAMVQIEKENASLKGVLPKNYAR
CHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCC
PELDKTRLGELIDLFSFNVGSKEARAKDVLGRVYEYFLKKFGTTEGEFYTPPAIVKLLVN
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
MIEPYNGRVYDPCCGSGGMFVQSAKFVEEHAGKIGNISIYGQEYVATTWRLAKMNLAIRG
HHCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHEEEEEEEEE
IDANLGERDGDTFTNDQHKTLRADYILANPPFNIKDWGQQHLIGDSRWQWGTPPATNANY
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCH
AWISHMISKLSPRGIAGFVLANGSLSTSRSEEYEIRKKILEEGLVDCIVAMPSQLFYDVS
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEEE
IPVSLWFVSKNKNGRKDKVLFIDARKMGYMETRKHRELTDEESEKIYSTYHAWRDDKDYQ
CCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHH
DIDGFCKSATLEEIRSHDYVLTPGRYVGIEEVEDDGIPFEEKMEKLTLELSELFEESKSL
HHHHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EEKIKENLRGIGYEL
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADLQLGFEDKLWQMADKLRGNIESSEYKHVILGLVFLKYISDSFTERYEEIKANYPGME
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EDRDAYESENVFFVPKDARWEYIKSQAKQSTIGQIIDNAMVQIEKENASLKGVLPKNYAR
CHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEECCCCCCCCC
PELDKTRLGELIDLFSFNVGSKEARAKDVLGRVYEYFLKKFGTTEGEFYTPPAIVKLLVN
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
MIEPYNGRVYDPCCGSGGMFVQSAKFVEEHAGKIGNISIYGQEYVATTWRLAKMNLAIRG
HHCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHEEEEEEEEE
IDANLGERDGDTFTNDQHKTLRADYILANPPFNIKDWGQQHLIGDSRWQWGTPPATNANY
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCH
AWISHMISKLSPRGIAGFVLANGSLSTSRSEEYEIRKKILEEGLVDCIVAMPSQLFYDVS
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEEE
IPVSLWFVSKNKNGRKDKVLFIDARKMGYMETRKHRELTDEESEKIYSTYHAWRDDKDYQ
CCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHH
DIDGFCKSATLEEIRSHDYVLTPGRYVGIEEVEDDGIPFEEKMEKLTLELSELFEESKSL
HHHHHHHHHHHHHHHCCCEEECCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EEKIKENLRGIGYEL
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]