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The map label for this gene is ackA

Identifier: 162447358

GI number: 162447358

Start: 518942

End: 520123

Strand: Direct

Name: ackA

Synonym: ACL_0496

Alternate gene names: 162447358

Gene position: 518942-520123 (Clockwise)

Preceding gene: 162447357

Following gene: 162447359

Centisome position: 34.67

GC content: 33.84

Gene sequence:

>1182_bases
ATGAAAATTTTATCGGTTAACGCTGGAAGTTCCAGTTTAAAGTTCCAATTATTACAAATGCCAGAAGAATTTGAAATCGC
ATCTGGTTTAGTTGAAAGAATTGGTAATAAAAATGCAGAATTTAAAATTAAATTTAACGGCTCATCTAAAACTCAAAGTG
ATTTAGTCGTTTTAGATCACTCAGTAGCTGTTGATTTAGTTATCAAAGGTTTACTAGAAAATAAGGTGATTGCTTCTTTA
GATGAAATTCAAGGCGTTGGACACCGTGTTGTTCAAGGTGGACAATTATTTAAAGAATCTGTAGTCATTGATGATGATGT
GGTTATCAAAATTGCATCTTTAAATGACTTGGCACCACTTCATAATCCAGCAAACATTATTGGTATTAATGCTTTTAGAA
AAGCGATATCAAATGTAATTCATGTTGCAGTGTTTGATACAACATTCCATCAAACTATGCCAGAAGAAAACTTCTTATAT
GGTACACCATATGAGTGGTATACAAAACATGGTGTTAGAAAATATGGTTTCCACGGTACATCACACCAATATGTATCTGA
ACTTGCACATGCACGTTTAGGCAAAGATCATTCAAGAATAATTGTTGCTCATATCGGTAATGGTGCATCTATTACAGCTG
TAAGAGATGGTAAGAGTATTGATACATCTATGGGCTTAACACCACTTGAAGGCTTCCCAACGGGAACACGTAGTGGTAAT
GTAGACCCAGCAATCTTCCAATTAATGCAACAAAAAGAAGGTTATTCATTAGAAAAAACTTTAAACGAGTTAAATAAAAA
TAGTGGATATCTAGGTATTTCAGGGGTTTCACATGACTCTAGAGATATTATTGCTGCAGCAGAAGGCGGCAACAAACGTG
CTCAGTTAGCACTTGATATTCAAGCTAAACGTATTGTTGATTACATTGCATCCTACTATGTTTTACTAGGTGGTTTAGAT
GCTTTAGTATTTACTGCAGGTATTGGAGAAAATGCAAAGGAAGTTAGAAAACTTATTTGTGACAGACTTGGTGTATTAGG
CATCAAACTTGATGATAATAAGAATAATTCAAGAGGCGATAAAGAAATTTCTAGTGATGCTTCAAATGTTAAAATTTGGG
TTATTCCTACAAATGAAGAAGTCATGATCGCTCGTGATGTATTAAGATTACAAAACAAATAG

Upstream 100 bases:

>100_bases
CAATTTATAATTATTTAATAATTTAAAAACTAAAATTATGTTAATACTTGAATATTTATTCATGTTGAGTTAAAATCAAA
TAAGATAGGAAGGTAATATT

Downstream 100 bases:

>100_bases
TATATTTAAGTCTAAAAGCTCTGATAATTTAGTGTTATCAGGGCTTTTATATTTCATTAAATAGTTTCTGTAAATGGAAA
AATCTAAAGTGTATTGACTA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKILSVNAGSSSLKFQLLQMPEEFEIASGLVERIGNKNAEFKIKFNGSSKTQSDLVVLDHSVAVDLVIKGLLENKVIASL
DEIQGVGHRVVQGGQLFKESVVIDDDVVIKIASLNDLAPLHNPANIIGINAFRKAISNVIHVAVFDTTFHQTMPEENFLY
GTPYEWYTKHGVRKYGFHGTSHQYVSELAHARLGKDHSRIIVAHIGNGASITAVRDGKSIDTSMGLTPLEGFPTGTRSGN
VDPAIFQLMQQKEGYSLEKTLNELNKNSGYLGISGVSHDSRDIIAAAEGGNKRAQLALDIQAKRIVDYIASYYVLLGGLD
ALVFTAGIGENAKEVRKLICDRLGVLGIKLDDNKNNSRGDKEISSDASNVKIWVIPTNEEVMIARDVLRLQNK

Sequences:

>Translated_393_residues
MKILSVNAGSSSLKFQLLQMPEEFEIASGLVERIGNKNAEFKIKFNGSSKTQSDLVVLDHSVAVDLVIKGLLENKVIASL
DEIQGVGHRVVQGGQLFKESVVIDDDVVIKIASLNDLAPLHNPANIIGINAFRKAISNVIHVAVFDTTFHQTMPEENFLY
GTPYEWYTKHGVRKYGFHGTSHQYVSELAHARLGKDHSRIIVAHIGNGASITAVRDGKSIDTSMGLTPLEGFPTGTRSGN
VDPAIFQLMQQKEGYSLEKTLNELNKNSGYLGISGVSHDSRDIIAAAEGGNKRAQLALDIQAKRIVDYIASYYVLLGGLD
ALVFTAGIGENAKEVRKLICDRLGVLGIKLDDNKNNSRGDKEISSDASNVKIWVIPTNEEVMIARDVLRLQNK
>Mature_393_residues
MKILSVNAGSSSLKFQLLQMPEEFEIASGLVERIGNKNAEFKIKFNGSSKTQSDLVVLDHSVAVDLVIKGLLENKVIASL
DEIQGVGHRVVQGGQLFKESVVIDDDVVIKIASLNDLAPLHNPANIIGINAFRKAISNVIHVAVFDTTFHQTMPEENFLY
GTPYEWYTKHGVRKYGFHGTSHQYVSELAHARLGKDHSRIIVAHIGNGASITAVRDGKSIDTSMGLTPLEGFPTGTRSGN
VDPAIFQLMQQKEGYSLEKTLNELNKNSGYLGISGVSHDSRDIIAAAEGGNKRAQLALDIQAKRIVDYIASYYVLLGGLD
ALVFTAGIGENAKEVRKLICDRLGVLGIKLDDNKNNSRGDKEISSDASNVKIWVIPTNEEVMIARDVLRLQNK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=44.1624365482233, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=42.9292929292929, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_ACHLI (A9NFI4)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001620490.1
- ProteinModelPortal:   A9NFI4
- SMR:   A9NFI4
- GeneID:   5803765
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_0496
- HOGENOM:   HBG285863
- OMA:   MILVINS
- ProtClustDB:   PRK00180
- BioCyc:   ALAI441768:ACL_0496-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 42934; Mature: 42934

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILSVNAGSSSLKFQLLQMPEEFEIASGLVERIGNKNAEFKIKFNGSSKTQSDLVVLDH
CEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEC
SVAVDLVIKGLLENKVIASLDEIQGVGHRVVQGGQLFKESVVIDDDVVIKIASLNDLAPL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHCEEECCCEEEEEECCCCCCCC
HNPANIIGINAFRKAISNVIHVAVFDTTFHQTMPEENFLYGTPYEWYTKHGVRKYGFHGT
CCCCCEEEHHHHHHHHHHHEEEEEEECHHHHCCCCCCCEECCCHHHHHHCCCHHHCCCCC
SHQYVSELAHARLGKDHSRIIVAHIGNGASITAVRDGKSIDTSMGLTPLEGFPTGTRSGN
CHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
VDPAIFQLMQQKEGYSLEKTLNELNKNSGYLGISGVSHDSRDIIAAAEGGNKRAQLALDI
CCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCEEEEEEEH
QAKRIVDYIASYYVLLGGLDALVFTAGIGENAKEVRKLICDRLGVLGIKLDDNKNNSRGD
HHHHHHHHHHHHHHHHCCHHHHEEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCC
KEISSDASNVKIWVIPTNEEVMIARDVLRLQNK
HHHCCCCCCEEEEEEECCCCEEHHHHHHHHCCC
>Mature Secondary Structure
MKILSVNAGSSSLKFQLLQMPEEFEIASGLVERIGNKNAEFKIKFNGSSKTQSDLVVLDH
CEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEC
SVAVDLVIKGLLENKVIASLDEIQGVGHRVVQGGQLFKESVVIDDDVVIKIASLNDLAPL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHCEEECCCEEEEEECCCCCCCC
HNPANIIGINAFRKAISNVIHVAVFDTTFHQTMPEENFLYGTPYEWYTKHGVRKYGFHGT
CCCCCEEEHHHHHHHHHHHEEEEEEECHHHHCCCCCCCEECCCHHHHHHCCCHHHCCCCC
SHQYVSELAHARLGKDHSRIIVAHIGNGASITAVRDGKSIDTSMGLTPLEGFPTGTRSGN
CHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
VDPAIFQLMQQKEGYSLEKTLNELNKNSGYLGISGVSHDSRDIIAAAEGGNKRAQLALDI
CCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCEEEEEEEH
QAKRIVDYIASYYVLLGGLDALVFTAGIGENAKEVRKLICDRLGVLGIKLDDNKNNSRGD
HHHHHHHHHHHHHHHHCCHHHHEEECCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCC
KEISSDASNVKIWVIPTNEEVMIARDVLRLQNK
HHHCCCCCCEEEEEEECCCCEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA