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The map label for this gene is rpiR [C]

Identifier: 162447131

GI number: 162447131

Start: 261344

End: 262189

Strand: Direct

Name: rpiR [C]

Synonym: ACL_0262

Alternate gene names: 162447131

Gene position: 261344-262189 (Clockwise)

Preceding gene: 162447130

Following gene: 162447132

Centisome position: 17.46

GC content: 31.8

Gene sequence:

>846_bases
ATGAGTGTAATGTTAAACATGCTGAAAAATAAAGAAGCACTAAGTATGGCTGAACGTATTGTTCTTGATTATTTAATTGA
GAATAAGACGTTGCTCAAAGATTTTAGCGTGGAGAAAATTGCAGAGGCGGCTTACACATCCCCGGCATCGGTTGTAAGAA
TGTGTAAAAAGTTAGGTTATAATGGTTTTAAAGACTTTAAAATCGATTTTATTCTTGCAAACTCTAAAGTAGAGATTCCT
GAAACAAGTGAATACACTGACGTTATTTTAATTAAAGATCAAAACAATGGAAAAAAGGCAATTGAAAATAATATTCGAGC
ACTAGAAGAAACCATTAATCTATATGATGAAAAAACGTATACCAAAGCTGCATCCTTAATTATGAATGCTAGAAAAATCT
TAATCTTTGGTAAAGGATCAAGTTTCTTAGTATGTAAAGACTTAGAAATGAAATTAAGACGTATTAATAAATTTTGTGTG
GCACAAGGTGAATCACATGACCAATTTGTGGATGCATCCTTTATTAATAATAAAGACGTCGTAATTTTCATATCAAACTC
TGGTAAAACTAAAGAAATTATTTCCTCAGCATTACTTGCTAAAGAAAATAAAACACCAATTATTAGTATCACAAGAATTG
GTTCAAGCATCCTTGCCGACATTTCGGATGTTGTGTTATACACTTCAGCATTAGAATCAGAATTTAGAAGTGCTGCGATG
ACTTCACGTATTTCTCAGATGTCCGTGGTGGATGCACTTTATGCAAAATGTGCATACACAGATATAGATCGTTCGATTCA
AGCACTTGAGACAACATATAGAACAATTAAAAAATTTAAAAGATAA

Upstream 100 bases:

>100_bases
TAAATATCATTTAGAAGAAAAAAGTGAATGTGTGATTAATAAAAACGGTTTCACTCATGTTATAATATAGATGAGGAAGA
TAAATGAGGTGTAGTGATAA

Downstream 100 bases:

>100_bases
TTCAAATGAGGGCACCTATAAAATAGGTGCCCTTTTTTTGAAAACATTTTTCTAAGTGTGAAAGAATCTAACGAAATTAA
GCGCTTACAAAAATATAGTA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSVMLNMLKNKEALSMAERIVLDYLIENKTLLKDFSVEKIAEAAYTSPASVVRMCKKLGYNGFKDFKIDFILANSKVEIP
ETSEYTDVILIKDQNNGKKAIENNIRALEETINLYDEKTYTKAASLIMNARKILIFGKGSSFLVCKDLEMKLRRINKFCV
AQGESHDQFVDASFINNKDVVIFISNSGKTKEIISSALLAKENKTPIISITRIGSSILADISDVVLYTSALESEFRSAAM
TSRISQMSVVDALYAKCAYTDIDRSIQALETTYRTIKKFKR

Sequences:

>Translated_281_residues
MSVMLNMLKNKEALSMAERIVLDYLIENKTLLKDFSVEKIAEAAYTSPASVVRMCKKLGYNGFKDFKIDFILANSKVEIP
ETSEYTDVILIKDQNNGKKAIENNIRALEETINLYDEKTYTKAASLIMNARKILIFGKGSSFLVCKDLEMKLRRINKFCV
AQGESHDQFVDASFINNKDVVIFISNSGKTKEIISSALLAKENKTPIISITRIGSSILADISDVVLYTSALESEFRSAAM
TSRISQMSVVDALYAKCAYTDIDRSIQALETTYRTIKKFKR
>Mature_280_residues
SVMLNMLKNKEALSMAERIVLDYLIENKTLLKDFSVEKIAEAAYTSPASVVRMCKKLGYNGFKDFKIDFILANSKVEIPE
TSEYTDVILIKDQNNGKKAIENNIRALEETINLYDEKTYTKAASLIMNARKILIFGKGSSFLVCKDLEMKLRRINKFCVA
QGESHDQFVDASFINNKDVVIFISNSGKTKEIISSALLAKENKTPIISITRIGSSILADISDVVLYTSALESEFRSAAMT
SRISQMSVVDALYAKCAYTDIDRSIQALETTYRTIKKFKR

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=257, Percent_Identity=24.9027237354086, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788767, Length=242, Percent_Identity=30.1652892561983, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788159, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082130, Length=285, Percent_Identity=24.2105263157895, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31487

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMLNMLKNKEALSMAERIVLDYLIENKTLLKDFSVEKIAEAAYTSPASVVRMCKKLGY
CHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCC
NGFKDFKIDFILANSKVEIPETSEYTDVILIKDQNNGKKAIENNIRALEETINLYDEKTY
CCCCCEEEEEEEECCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHH
TKAASLIMNARKILIFGKGSSFLVCKDLEMKLRRINKFCVAQGESHDQFVDASFINNKDV
HHHHHHHHCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEHHCCCCCCE
VIFISNSGKTKEIISSALLAKENKTPIISITRIGSSILADISDVVLYTSALESEFRSAAM
EEEEECCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSRISQMSVVDALYAKCAYTDIDRSIQALETTYRTIKKFKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVMLNMLKNKEALSMAERIVLDYLIENKTLLKDFSVEKIAEAAYTSPASVVRMCKKLGY
HHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCC
NGFKDFKIDFILANSKVEIPETSEYTDVILIKDQNNGKKAIENNIRALEETINLYDEKTY
CCCCCEEEEEEEECCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHH
TKAASLIMNARKILIFGKGSSFLVCKDLEMKLRRINKFCVAQGESHDQFVDASFINNKDV
HHHHHHHHCCEEEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEHHCCCCCCE
VIFISNSGKTKEIISSALLAKENKTPIISITRIGSSILADISDVVLYTSALESEFRSAAM
EEEEECCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSRISQMSVVDALYAKCAYTDIDRSIQALETTYRTIKKFKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]