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The map label for this gene is infA

Identifier: 162446980

GI number: 162446980

Start: 95926

End: 96144

Strand: Direct

Name: infA

Synonym: ACL_0110

Alternate gene names: 162446980

Gene position: 95926-96144 (Clockwise)

Preceding gene: 162446979

Following gene: 162446981

Centisome position: 6.41

GC content: 36.07

Gene sequence:

>219_bases
ATGGCAAGAGAAGATTTAATAGAAGTTGAAGCAAAGGTTAAAGAAATTTTACCGAACACAAAGTTTATAGTTGAGCTAGA
CAACGGTCACACCGTTGTAGCACACGTATCTGGTAAAATCCGTATCCACAACATACGCATTTTACCTGGTGATAAAGTAA
CAGTTGAATTATCACCATATGATTTATCACGCGGACGTATAACATACCGCAAAAAATAA

Upstream 100 bases:

>100_bases
CAACAGTTACACAAGACAAATCATATAGTGCACATTTCGAGCATACGGTACTTGTAACCGAAACAGGCTATGAAGTATTG
ACTAAAACAAAGGAGTAATT

Downstream 100 bases:

>100_bases
GGAGCAATTAAAATGAAAGTTAAAGCATCAGTTAAAAAGCGCAGCGCAGATGACATCATTGTGCGCCGCAAAGGTCGCGT
ATACGTGATCAACAAAAAAA

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MAREDLIEVEAKVKEILPNTKFIVELDNGHTVVAHVSGKIRIHNIRILPGDKVTVELSPYDLSRGRITYRKK

Sequences:

>Translated_72_residues
MAREDLIEVEAKVKEILPNTKFIVELDNGHTVVAHVSGKIRIHNIRILPGDKVTVELSPYDLSRGRITYRKK
>Mature_71_residues
AREDLIEVEAKVKEILPNTKFIVELDNGHTVVAHVSGKIRIHNIRILPGDKVTVELSPYDLSRGRITYRKK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:
GO:0003723: Translation initiation factor IF-1
GO:0003743: Translation initiation factor IF-1
GO:0005737: Translation initiation factor IF-1
GO:0006412: Translation initiation factor IF-1
GO:0006413: Translation initiation factor IF-1

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=65.2777777777778, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_ACHLI (A9NEF6)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001620112.1
- ProteinModelPortal:   A9NEF6
- SMR:   A9NEF6
- GeneID:   5804126
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_0110
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- BioCyc:   ALAI441768:ACL_0110-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8222; Mature: 8091

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREDLIEVEAKVKEILPNTKFIVELDNGHTVVAHVSGKIRIHNIRILPGDKVTVELSPY
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCEEEEEEEEECCCCEEEEEECCC
DLSRGRITYRKK
CCCCCEEEEECC
>Mature Secondary Structure 
AREDLIEVEAKVKEILPNTKFIVELDNGHTVVAHVSGKIRIHNIRILPGDKVTVELSPY
CCCHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCEEEEEEEEECCCCEEEEEECCC
DLSRGRITYRKK
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA