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The map label for this gene is fre [H]

Identifier: 162418986

GI number: 162418986

Start: 1983008

End: 1983751

Strand: Direct

Name: fre [H]

Synonym: YpAngola_A1910

Alternate gene names: 162418986

Gene position: 1983008-1983751 (Clockwise)

Preceding gene: 162418443

Following gene: 162420714

Centisome position: 44.03

GC content: 48.66

Gene sequence:

>744_bases
TTGTACTTGGTTTTGCATTTGATGACCCGACAGAGGGAAGGCATGACAACTTTAAGCTGTAAAGTAACCTCCGTAGAGGC
CATTACCGATACGGTGTACCGGGTGCAATTGGTACCTGAATCTTCTTTTTCTTTCCGCGCCGGGCAGTATTTGATGGTAG
TGATGGATGAGCGTGATAAGCGCCCATTCTCGATGGCTTCCACACCGTTTCAGCAGGACTTTATCGAGTTACATATCGGT
GCTTCGGAGCTGAATTTGTACGCAATGGCAGTGATGGATCGCATCCTAAAAGAGAAAAAACTGGATGTTGATATTCCTCA
TGGAGATGCCTGGTTCCGTGAAGGGAGCAAGCGTCCGTTGGTTCTGATTGCTGGCGGTACTGGCTTCTCTTATGCGCGAT
CCATCTTGTTAGCCGCGTTAGCGGAACAACCTGATCGCGAAGTCTCTATCTATTGGGGCGGGCGCGAAGCGGTACACCTG
TATGATTTAGGTGAGTTGGAAGCACTATCGATTAAGTATCCGCAACTGAAAGTCATTCCCGTAGTAGAACAACCGGAAGA
GGGTTGGCGTGGGCGCACAGGGACTGTACTGAGTGCTGTACTACAAGATTACGGTTCTTTAGCTGAGCAGGATATTTACA
TCGCGGGGCGTTTTGAAATGGCTAAAATCGCCCGTGAGCGTTTTTGTGTGGAGCGTGGCGCACAGGAAGAACATATCTTT
GGTGATGCTTTTGCCTTTATCTAA

Upstream 100 bases:

>100_bases
AATTAAGATGGACGAAGACGTCCGTGCCCGTATTGATGCTCTGTGGGATGAGCTGGCCATTTTCAGTGACAAAGACGCGA
AACGCTAACTAGCGTCGGCT

Downstream 100 bases:

>100_bases
AAGCGATAAAAAGCCCGCCTCTGACCGGCGGGGAAATAGCAACTAAACACGATATACCTCAGTTATCAGGGCCTACGTTC
AGGCCCCTAATTTCTTGATG

Product: FMN reductase

Products: NA

Alternate protein names: Aquacobalamin reductase; FMN reductase; Ferrisiderophore reductase C; NAD(P)H:flavin oxidoreductase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MYLVLHLMTRQREGMTTLSCKVTSVEAITDTVYRVQLVPESSFSFRAGQYLMVVMDERDKRPFSMASTPFQQDFIELHIG
ASELNLYAMAVMDRILKEKKLDVDIPHGDAWFREGSKRPLVLIAGGTGFSYARSILLAALAEQPDREVSIYWGGREAVHL
YDLGELEALSIKYPQLKVIPVVEQPEEGWRGRTGTVLSAVLQDYGSLAEQDIYIAGRFEMAKIARERFCVERGAQEEHIF
GDAFAFI

Sequences:

>Translated_247_residues
MYLVLHLMTRQREGMTTLSCKVTSVEAITDTVYRVQLVPESSFSFRAGQYLMVVMDERDKRPFSMASTPFQQDFIELHIG
ASELNLYAMAVMDRILKEKKLDVDIPHGDAWFREGSKRPLVLIAGGTGFSYARSILLAALAEQPDREVSIYWGGREAVHL
YDLGELEALSIKYPQLKVIPVVEQPEEGWRGRTGTVLSAVLQDYGSLAEQDIYIAGRFEMAKIARERFCVERGAQEEHIF
GDAFAFI
>Mature_247_residues
MYLVLHLMTRQREGMTTLSCKVTSVEAITDTVYRVQLVPESSFSFRAGQYLMVVMDERDKRPFSMASTPFQQDFIELHIG
ASELNLYAMAVMDRILKEKKLDVDIPHGDAWFREGSKRPLVLIAGGTGFSYARSILLAALAEQPDREVSIYWGGREAVHL
YDLGELEALSIKYPQLKVIPVVEQPEEGWRGRTGTVLSAVLQDYGSLAEQDIYIAGRFEMAKIARERFCVERGAQEEHIF
GDAFAFI

Specific function: Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides. Seems to reduces the complexed Fe(3+) iron of siderophores to Fe(2+), thus releasing it from the chelator [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI2367314, Length=233, Percent_Identity=77.6824034334764, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.16.1.3; =1.5.1.29 [H]

Molecular weight: Translated: 27951; Mature: 27951

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVLHLMTRQREGMTTLSCKVTSVEAITDTVYRVQLVPESSFSFRAGQYLMVVMDERDK
CEEEEEEHHHCCCCCEEEEEEEEEHHHHHCEEEEEEEECCCCCCCCCCCEEEEEEECCCC
RPFSMASTPFQQDFIELHIGASELNLYAMAVMDRILKEKKLDVDIPHGDAWFREGSKRPL
CCCCCCCCCHHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCE
VLIAGGTGFSYARSILLAALAEQPDREVSIYWGGREAVHLYDLGELEALSIKYPQLKVIP
EEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEEEEECCCEEEEE
VVEQPEEGWRGRTGTVLSAVLQDYGSLAEQDIYIAGRFEMAKIARERFCVERGAQEEHIF
EEECCCCCCCCCCHHHHHHHHHHHHCHHHCCEEEECCHHHHHHHHHHHHHHCCCCCHHEE
GDAFAFI
CHHHHCC
>Mature Secondary Structure
MYLVLHLMTRQREGMTTLSCKVTSVEAITDTVYRVQLVPESSFSFRAGQYLMVVMDERDK
CEEEEEEHHHCCCCCEEEEEEEEEHHHHHCEEEEEEEECCCCCCCCCCCEEEEEEECCCC
RPFSMASTPFQQDFIELHIGASELNLYAMAVMDRILKEKKLDVDIPHGDAWFREGSKRPL
CCCCCCCCCHHHCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCE
VLIAGGTGFSYARSILLAALAEQPDREVSIYWGGREAVHLYDLGELEALSIKYPQLKVIP
EEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEEEEECCCEEEEE
VVEQPEEGWRGRTGTVLSAVLQDYGSLAEQDIYIAGRFEMAKIARERFCVERGAQEEHIF
EEECCCCCCCCCCHHHHHHHHHHHHCHHHCCEEEECCHHHHHHHHHHHHHHCCCCCHHEE
GDAFAFI
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]