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The map label for this gene is ubiC

Identifier: 162382790

GI number: 162382790

Start: 3722139

End: 3722672

Strand: Reverse

Name: ubiC

Synonym: SG2144

Alternate gene names: 162382790

Gene position: 3722672-3722139 (Counterclockwise)

Preceding gene: 85060123

Following gene: 85060121

Centisome position: 89.25

GC content: 65.36

Gene sequence:

>534_bases
ATGCAGGATCAGGCCATAGTGGCGATACTTGACGGTATTCGCTGGCTCCAGGAGCCGCCGGTGTGGCCCGACGACGCCAC
GCGAAGCTGGCTGACCGAGCGCGGGTCGATGACTCAACGTCTTGAAAAGCACTGCGGGAAAATTCGCGTCCGGCGCTATC
GTGAAGGGTTTGTCACCGCCTGCATCGAAGCGTGGGAGGCGGCGTTATTGCCGGATTGCGGGCGATTCTGGCTCCGGGAG
GTGGTGCTGTATGGTCATGACCGTCCTTGGTTGACCGCGCGCACGTTGGTGCCCGCCGCCGCGGAGGCGGGGCCGGCGCA
GCAGGTGCTGAGCCTGGGGGATGTGCCGCTGGGGCAATGGCTGTTCCGCCACCGTCCGCCGGCGCGCGACGTTATCCAAT
TCGGCCGGGTTGGCACGTTATGGGCGCGACGCGCCCGCCTGCGGCTTACCGAGGGGCAACCGTTGCTGCTGACGGAAGCG
TTTTTACCCGACTGCCCGCTGTATATTAGCGGCGGCGATGCGCCACAACAGTAA

Upstream 100 bases:

>100_bases
CCCGCAGTGGTGCATGGCGCGCCGGATTGTGTTTACGACATGTCAATGAATGGAGGTTCTGGGCTACAATGAAATCTTTG
AGTACGGGAGCGCGGACCCT

Downstream 100 bases:

>100_bases
AGGAGAATTCCGTTGGATCACAGTCTGACACAGGATAGATGGCAGGCATGGTGCCGTTTGATGCGAATCGATAAGCCTAT
CGGTTCGCTGCTGCTGCTGT

Product: chorismate pyruvate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MQDQAIVAILDGIRWLQEPPVWPDDATRSWLTERGSMTQRLEKHCGKIRVRRYREGFVTACIEAWEAALLPDCGRFWLRE
VVLYGHDRPWLTARTLVPAAAEAGPAQQVLSLGDVPLGQWLFRHRPPARDVIQFGRVGTLWARRARLRLTEGQPLLLTEA
FLPDCPLYISGGDAPQQ

Sequences:

>Translated_177_residues
MQDQAIVAILDGIRWLQEPPVWPDDATRSWLTERGSMTQRLEKHCGKIRVRRYREGFVTACIEAWEAALLPDCGRFWLRE
VVLYGHDRPWLTARTLVPAAAEAGPAQQVLSLGDVPLGQWLFRHRPPARDVIQFGRVGTLWARRARLRLTEGQPLLLTEA
FLPDCPLYISGGDAPQQ
>Mature_177_residues
MQDQAIVAILDGIRWLQEPPVWPDDATRSWLTERGSMTQRLEKHCGKIRVRRYREGFVTACIEAWEAALLPDCGRFWLRE
VVLYGHDRPWLTARTLVPAAAEAGPAQQVLSLGDVPLGQWLFRHRPPARDVIQFGRVGTLWARRARLRLTEGQPLLLTEA
FLPDCPLYISGGDAPQQ

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=159, Percent_Identity=44.0251572327044, Blast_Score=123, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_SODGM (Q2NR06)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_455824.2
- ProteinModelPortal:   Q2NR06
- SMR:   Q2NR06
- STRING:   Q2NR06
- GeneID:   3868253
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG2144
- NMPDR:   fig|343509.6.peg.4716
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- PhylomeDB:   Q2NR06
- ProtClustDB:   PRK11655
- BioCyc:   SGLO343509:SG2144-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 20119; Mature: 20119

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: BINDING 37-37 BINDING 79-79 BINDING 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDQAIVAILDGIRWLQEPPVWPDDATRSWLTERGSMTQRLEKHCGKIRVRRYREGFVTA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
CIEAWEAALLPDCGRFWLREVVLYGHDRPWLTARTLVPAAAEAGPAQQVLSLGDVPLGQW
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHCCCHHHHHHHHCCCCHHHH
LFRHRPPARDVIQFGRVGTLWARRARLRLTEGQPLLLTEAFLPDCPLYISGGDAPQQ
HHHCCCCHHHHHHHCCHHHHHHHHHHEEECCCCCEEEEHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MQDQAIVAILDGIRWLQEPPVWPDDATRSWLTERGSMTQRLEKHCGKIRVRRYREGFVTA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
CIEAWEAALLPDCGRFWLREVVLYGHDRPWLTARTLVPAAAEAGPAQQVLSLGDVPLGQW
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHCCCHHHHHHHHCCCCHHHH
LFRHRPPARDVIQFGRVGTLWARRARLRLTEGQPLLLTEAFLPDCPLYISGGDAPQQ
HHHCCCCHHHHHHHCCHHHHHHHHHHEEECCCCCEEEEHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA