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The map label for this gene is nbaJ

Identifier: 162330293

GI number: 162330293

Start: 3253918

End: 3254805

Strand: Reverse

Name: nbaJ

Synonym: GTNG_3152

Alternate gene names: 162330293

Gene position: 3254805-3253918 (Counterclockwise)

Preceding gene: 138896790

Following gene: 138896788

Centisome position: 91.68

GC content: 56.31

Gene sequence:

>888_bases
GTGGCTAAAGTGAAAGTGGCAATTCTCGGTTCCGGCAATATCGGCACCGATTTGATGATCAAGCTGGAGAGGTCGTCGCA
TCTGGAGTTGACTGCGATGATTGGCATCGACCCCGAATCAGACGGGCTGAAAAAGGCAAAAACGAAGGGATATTACGTGT
TCGACGGAGGGTTGAAACAGTTTCTCAGTGAGGCCTCAGAGCTGGCCGACCTTGTATTTGACGCCACCTCCGCCAAGGCC
CACGTTCGCCATGCCAAAGCTCTGAGAGAGGCGGGGAAGATGGTCATCGACCTGACCCCGGCGGCGGTGGGACCGTACGT
GGTGCCGTCCGTCAACCTGGGGGATTACTTGGAAGAATCCAACCTCAACCTAATCACCTGCGGGGGTCAGGCGACGATTC
CGATCGTGCACGCGATCAACCGGGTGGCGCAGGTTCACTATTCGGAGATTGTGGCCACCATTGCAAGTAAGAGCGCCGGA
CCAGGCACCCGGGCTAACATCGACGAGTTCACTCAGACGACAGCTCATGGCTTGGAGGCAATTGGCGGCGCGAAAAAAGG
AAAGGCGATCATCATTCTCAATCCAGCCGAACCGCCGATTATTATGCGAAACGCGGTGTACGCCCTGGTGGAGTGTGAAC
AGATGGACGAGGTAGCCATCGCCCGGTCGGTTCAGGAGACTGTTGCTTACATCCAGTCCTATGTACCTGGGTACCGTCTG
CGCACTGAGCCGCTATTTGAAGGCAACAAGGTTACGGTGTTCGTAGAGGTGGAGGGGGCTGGCGACTATCTCCCGACGTA
TTCTGGCAACCTGGACATCATGACGGCCACTGCCATCAAGGTGGCGGAGGAATGGGTTCAACACCGTGTGAAAGCTGCTT
CGGTTTGA

Upstream 100 bases:

>100_bases
GTGATTCTCTCCGGTGCTTTGTCGGCTGCGGTCGATGCCGCACCTGGTGACTATTTTCATGCACGGTTCGCCTATCTTGG
AGAGGTAGGGGTGAGATTTC

Downstream 100 bases:

>100_bases
TGGCCGCTTCGGCACGACGTGCGAGAAGGAGGAGAGAGAGTGAGCAGCGAACGCGATATATGGATTACGGAAGTGGCGCT
TCGTGACGGGAGCCACGCGA

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAKVKVAILGSGNIGTDLMIKLERSSHLELTAMIGIDPESDGLKKAKTKGYYVFDGGLKQFLSEASELADLVFDATSAKA
HVRHAKALREAGKMVIDLTPAAVGPYVVPSVNLGDYLEESNLNLITCGGQATIPIVHAINRVAQVHYSEIVATIASKSAG
PGTRANIDEFTQTTAHGLEAIGGAKKGKAIIILNPAEPPIIMRNAVYALVECEQMDEVAIARSVQETVAYIQSYVPGYRL
RTEPLFEGNKVTVFVEVEGAGDYLPTYSGNLDIMTATAIKVAEEWVQHRVKAASV

Sequences:

>Translated_295_residues
MAKVKVAILGSGNIGTDLMIKLERSSHLELTAMIGIDPESDGLKKAKTKGYYVFDGGLKQFLSEASELADLVFDATSAKA
HVRHAKALREAGKMVIDLTPAAVGPYVVPSVNLGDYLEESNLNLITCGGQATIPIVHAINRVAQVHYSEIVATIASKSAG
PGTRANIDEFTQTTAHGLEAIGGAKKGKAIIILNPAEPPIIMRNAVYALVECEQMDEVAIARSVQETVAYIQSYVPGYRL
RTEPLFEGNKVTVFVEVEGAGDYLPTYSGNLDIMTATAIKVAEEWVQHRVKAASV
>Mature_294_residues
AKVKVAILGSGNIGTDLMIKLERSSHLELTAMIGIDPESDGLKKAKTKGYYVFDGGLKQFLSEASELADLVFDATSAKAH
VRHAKALREAGKMVIDLTPAAVGPYVVPSVNLGDYLEESNLNLITCGGQATIPIVHAINRVAQVHYSEIVATIASKSAGP
GTRANIDEFTQTTAHGLEAIGGAKKGKAIIILNPAEPPIIMRNAVYALVECEQMDEVAIARSVQETVAYIQSYVPGYRLR
TEPLFEGNKVTVFVEVEGAGDYLPTYSGNLDIMTATAIKVAEEWVQHRVKAASV

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=315, Percent_Identity=53.6507936507937, Blast_Score=320, Evalue=5e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_GEOTN (A4IT43)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001127242.2
- ProteinModelPortal:   A4IT43
- STRING:   A4IT43
- GeneID:   4968078
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_3152
- NMPDR:   fig|420246.5.peg.3020
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- ProtClustDB:   PRK08300
- BioCyc:   GTHE420246:GTNG_3152-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 31583; Mature: 31451

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: BINDING 270-270

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVKVAILGSGNIGTDLMIKLERSSHLELTAMIGIDPESDGLKKAKTKGYYVFDGGLKQ
CCEEEEEEEECCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCHHHCCCCEEEECCHHHH
FLSEASELADLVFDATSAKAHVRHAKALREAGKMVIDLTPAAVGPYVVPSVNLGDYLEES
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCHHHHHHHC
NLNLITCGGQATIPIVHAINRVAQVHYSEIVATIASKSAGPGTRANIDEFTQTTAHGLEA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
IGGAKKGKAIIILNPAEPPIIMRNAVYALVECEQMDEVAIARSVQETVAYIQSYVPGYRL
HCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RTEPLFEGNKVTVFVEVEGAGDYLPTYSGNLDIMTATAIKVAEEWVQHRVKAASV
ECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKVKVAILGSGNIGTDLMIKLERSSHLELTAMIGIDPESDGLKKAKTKGYYVFDGGLKQ
CEEEEEEEECCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCHHHCCCCEEEECCHHHH
FLSEASELADLVFDATSAKAHVRHAKALREAGKMVIDLTPAAVGPYVVPSVNLGDYLEES
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCHHHHHHHC
NLNLITCGGQATIPIVHAINRVAQVHYSEIVATIASKSAGPGTRANIDEFTQTTAHGLEA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
IGGAKKGKAIIILNPAEPPIIMRNAVYALVECEQMDEVAIARSVQETVAYIQSYVPGYRL
HCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RTEPLFEGNKVTVFVEVEGAGDYLPTYSGNLDIMTATAIKVAEEWVQHRVKAASV
ECCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA