Click here to switch to the map view.

The map label for this gene is fae-hps [H]

Identifier: 162319793

GI number: 162319793

Start: 998045

End: 999256

Strand: Reverse

Name: fae-hps [H]

Synonym: Mlab_0996

Alternate gene names: 162319793

Gene position: 999256-998045 (Counterclockwise)

Preceding gene: 124485819

Following gene: 124485807

Centisome position: 55.36

GC content: 54.21

Gene sequence:

>1212_bases
ATGTTCTTAATTGGTGAAGCACTCGTCGGCGATGGAGCGGAACTCGCTCACATCGACCTTATGATCGGAGATAAAAACGG
CCCGGTCGGCATGTCATTCGCAAATGGTCTGACCCAGCTTTCCGCCGGCCACACTCCTCTTCTCGGCGTTATCCGCCCCA
ACCTTCTGCCAAAACCGGCAGTTCTGATCGTCCCCAAAGTAACCCTCAAACACACCGAGCAGGTTACCCAGATCTTTGGT
CCCGCACAGGCTGCGGTCTCCAAAGCAATAGCAGATGCATTGGAAGACGGCGTTTTCGCAGGAATGGATGTTGAGGAAAA
CGTCATTGTTGCAAGTGTTTTCATCGACCCCTCGGCAAAAGACTTCAATAAATTGTACCGTTTCAACTACGGAGCAACGC
GCCTTGCCCTCTCACGCGCTCTCGATAAGTTCCCGGACACCACCACCGTTCTGAAAGAGAAGGACAGAGCAGCTCACGGC
GTCATGGGCTTCAAGGTCCAGCGTCTGTGGAACCCGCCCTACCTCCAGGTCGCCATGGATCTTGTCGACATGAAGCAGGT
CGAGCGTGTTTTAACCGGCGTCCCGCAGAACGACCACGTCATCTTCGAGGCAGGTACCCCGCTGATCAAACAGTTCGGTC
TCAGTGTTATCAATGAGATCAGAAAGATCCGCCCGAACTGTTTCATCGTTGCCGACCTGAAGACCCTGGATACGGGTAAC
CTTGAGGCACGCATGGTCTCGAACGCCGGCGGAGACGCCGCAGTCGTTTCCGGCCTTGCACCGGTAGAAACCATCGCAGC
CTTCATCAAAGAAGCAAAGAAGTGCGGCATCTACGCGATCATCGACATGCTCAATGTCGAAGAGCCTGCAAAACTCATCG
AGTCCCTCGGTCAGATGGGCGGCGCAGCACTTCTCCCGCAGTATGTCGAGATGCACCGTGCGATCGATAAGGAATCCACC
GGCGACTACAGCTGGGGTGACATCAAGAAGATCAAGGAAGTTGCAAAGACATACGATGCAAAGATCCTTGTTGCGACTGC
AGGCGGTATCCGTCAGCCGGTCGTCAAGAAAGCAATTGCAGCAGGAGCAGATATCGTTGTTGTCGGCAGAGCGATCACCG
CAAGCAAGGACATCAAGAATGCAGCAGAGAGCTTCCTCGAGGAACTCGACTCGGAAGAGATCGACCAGTTCCGTATCATG
ACCGACTTCTAA

Upstream 100 bases:

>100_bases
GTTATCATATATGAAATATAGGAACGCTATATCCTCTATTGGTGGTTGAATGAAGTCTTTATACCCTCCCGGCGCTAACA
CTACTGCAGAGATTATACCT

Downstream 100 bases:

>100_bases
AGCGGTCATACCCGCGGCTTTTGCCGCCAGCCTATTTTTTTTGATCGTTCCTGTATCTTCAGCAGATACGCCGGCGTCTG
CAGAACTGATCCATTCAAAA

Product: bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase

Products: NA

Alternate protein names: Formaldehyde-activating enzyme; Fae; 3-hexulose-6-phosphate synthase; HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MFLIGEALVGDGAELAHIDLMIGDKNGPVGMSFANGLTQLSAGHTPLLGVIRPNLLPKPAVLIVPKVTLKHTEQVTQIFG
PAQAAVSKAIADALEDGVFAGMDVEENVIVASVFIDPSAKDFNKLYRFNYGATRLALSRALDKFPDTTTVLKEKDRAAHG
VMGFKVQRLWNPPYLQVAMDLVDMKQVERVLTGVPQNDHVIFEAGTPLIKQFGLSVINEIRKIRPNCFIVADLKTLDTGN
LEARMVSNAGGDAAVVSGLAPVETIAAFIKEAKKCGIYAIIDMLNVEEPAKLIESLGQMGGAALLPQYVEMHRAIDKEST
GDYSWGDIKKIKEVAKTYDAKILVATAGGIRQPVVKKAIAAGADIVVVGRAITASKDIKNAAESFLEELDSEEIDQFRIM
TDF

Sequences:

>Translated_403_residues
MFLIGEALVGDGAELAHIDLMIGDKNGPVGMSFANGLTQLSAGHTPLLGVIRPNLLPKPAVLIVPKVTLKHTEQVTQIFG
PAQAAVSKAIADALEDGVFAGMDVEENVIVASVFIDPSAKDFNKLYRFNYGATRLALSRALDKFPDTTTVLKEKDRAAHG
VMGFKVQRLWNPPYLQVAMDLVDMKQVERVLTGVPQNDHVIFEAGTPLIKQFGLSVINEIRKIRPNCFIVADLKTLDTGN
LEARMVSNAGGDAAVVSGLAPVETIAAFIKEAKKCGIYAIIDMLNVEEPAKLIESLGQMGGAALLPQYVEMHRAIDKEST
GDYSWGDIKKIKEVAKTYDAKILVATAGGIRQPVVKKAIAAGADIVVVGRAITASKDIKNAAESFLEELDSEEIDQFRIM
TDF
>Mature_403_residues
MFLIGEALVGDGAELAHIDLMIGDKNGPVGMSFANGLTQLSAGHTPLLGVIRPNLLPKPAVLIVPKVTLKHTEQVTQIFG
PAQAAVSKAIADALEDGVFAGMDVEENVIVASVFIDPSAKDFNKLYRFNYGATRLALSRALDKFPDTTTVLKEKDRAAHG
VMGFKVQRLWNPPYLQVAMDLVDMKQVERVLTGVPQNDHVIFEAGTPLIKQFGLSVINEIRKIRPNCFIVADLKTLDTGN
LEARMVSNAGGDAAVVSGLAPVETIAAFIKEAKKCGIYAIIDMLNVEEPAKLIESLGQMGGAALLPQYVEMHRAIDKEST
GDYSWGDIKKIKEVAKTYDAKILVATAGGIRQPVVKKAIAAGADIVVVGRAITASKDIKNAAESFLEELDSEEIDQFRIM
TDF

Specific function: Catalyzes the formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR020868
- InterPro:   IPR014826
- InterPro:   IPR001754
- InterPro:   IPR020568
- InterPro:   IPR011060 [H]

Pfam domain/function: PF08714 Fae; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 43440; Mature: 43440

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLIGEALVGDGAELAHIDLMIGDKNGPVGMSFANGLTQLSAGHTPLLGVIRPNLLPKPA
CEEECCCHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEHEECCCCCCCCC
VLIVPKVTLKHTEQVTQIFGPAQAAVSKAIADALEDGVFAGMDVEENVIVASVFIDPSAK
EEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEEECCCHH
DFNKLYRFNYGATRLALSRALDKFPDTTTVLKEKDRAAHGVMGFKVQRLWNPPYLQVAMD
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHH
LVDMKQVERVLTGVPQNDHVIFEAGTPLIKQFGLSVINEIRKIRPNCFIVADLKTLDTGN
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECEECCCCC
LEARMVSNAGGDAAVVSGLAPVETIAAFIKEAKKCGIYAIIDMLNVEEPAKLIESLGQMG
CEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHEEHHHHCCCHHHHHHHHHHHCC
GAALLPQYVEMHRAIDKESTGDYSWGDIKKIKEVAKTYDAKILVATAGGIRQPVVKKAIA
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
AGADIVVVGRAITASKDIKNAAESFLEELDSEEIDQFRIMTDF
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECC
>Mature Secondary Structure
MFLIGEALVGDGAELAHIDLMIGDKNGPVGMSFANGLTQLSAGHTPLLGVIRPNLLPKPA
CEEECCCHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCEEHEECCCCCCCCC
VLIVPKVTLKHTEQVTQIFGPAQAAVSKAIADALEDGVFAGMDVEENVIVASVFIDPSAK
EEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEEECCCHH
DFNKLYRFNYGATRLALSRALDKFPDTTTVLKEKDRAAHGVMGFKVQRLWNPPYLQVAMD
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHH
LVDMKQVERVLTGVPQNDHVIFEAGTPLIKQFGLSVINEIRKIRPNCFIVADLKTLDTGN
HHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECEECCCCC
LEARMVSNAGGDAAVVSGLAPVETIAAFIKEAKKCGIYAIIDMLNVEEPAKLIESLGQMG
CEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHCCHHEEHHHHCCCHHHHHHHHHHHCC
GAALLPQYVEMHRAIDKESTGDYSWGDIKKIKEVAKTYDAKILVATAGGIRQPVVKKAIA
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
AGADIVVVGRAITASKDIKNAAESFLEELDSEEIDQFRIMTDF
CCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA