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The map label for this gene is ywlC [H]

Identifier: 162149092

GI number: 162149092

Start: 3412911

End: 3413927

Strand: Direct

Name: ywlC [H]

Synonym: GDI_3322

Alternate gene names: 162149092

Gene position: 3412911-3413927 (Clockwise)

Preceding gene: 162149091

Following gene: 162149093

Centisome position: 86.53

GC content: 74.63

Gene sequence:

>1017_bases
ATGATCCAACCGAACCAACGGCTTGAGCGGACGGGCAGAGGAGTCATGACAGAGCGTCTGGAGGCAAACGACGCCGGCAT
CGCCCGGGCGGCCGATCTGCTGCGGGCGGGGGGATTGGTGGCATTCGGGACCGAGACCGTCTACGGCCTGGGCGCGGACG
CCACCAACGACACCGCCGTGGCACGCATCTTCGCCGCCAAGGAACGCCCGCGCTTCAACCCGCTGATCAGCCATTTCCCC
GATGCCGAGGCGGCCTTCGCCCAGGCCGCGCCCAACGACGTGGCGCGGCGCCTGGCCGAACGGTTCTGGCCCGGGCCGCT
GACGATGGTGCTGCCGCGCCAGCCAGGCAGCACCATTTCGGACCTCGCCGCCGCCGGCCTGCCGTCGGTGGCGGTGCGCG
TGCCGCGCGGCGCCATCACCACCGCCCTGCTGCGCGCCGTGGGCCGGCCGGTGGCGGCGCCTTCGGCCAACCTGTCGGGC
CGGGTCAGCCCCTCGGACGCCTATCACGTGCTGCGGGGCCTGTCCGGCCGCATCGATGCGGTCCTGGATTCCGGCCCCTG
TCCGGTCGGGGTCGAAAGCACGGTGCTGGACCTGACGGGCACCGCGCCGATGCTGCTGCGTCCCGGCGGCGTGACGGTCG
AGGCGTTGAGCGAGGTCTGCGGCCCGATCTCGCACCCCGACGATTATGCCGACACGCTGCCGCTGTCGCCCGGCCGCCTG
GCCTCGCACTACGCCCCGGGCCTGCCGGTGCGGCTGGACGCCCATGACGTGGCGGCGGACGAGGCCCTGCTGGCCTTCGG
GCCGGAACTGCCCGGCGCCGGCCTGGTGTGGAACCTCAGCCCCGCCGGACGGCTGGACGAGGCCGCCGCCCGCCTGTTCG
CCGGCCTGCGCTTCCTGGACAGCGAGGGCGCGCGGCGCGGCCTGGTCCGCATCGCCGCGATGCCGATCCCGCGCGTCGGG
CTGGGCATGGCCATCCGCGACCGGCTGCGCCGCGCGGCCTCTCCCCGGCCGGCATGA

Upstream 100 bases:

>100_bases
CCTGCTGGACGGCACGCCCCTGCGCTACGGGAAGCCCGACTGGCGCAACCCGCATTTTATATGTGCGGGAAAGCGGGAGC
ATTCATGAGCGCACCGCGTT

Downstream 100 bases:

>100_bases
CGGGACACCCGCATGACGACCGTTCCCCTTCCCGCTGATCCGTGGCCATGAGCGACAAGTTCGACCCCAAGGAACTGAAG
ATCCTGTCGGATATCCTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIQPNQRLERTGRGVMTERLEANDAGIARAADLLRAGGLVAFGTETVYGLGADATNDTAVARIFAAKERPRFNPLISHFP
DAEAAFAQAAPNDVARRLAERFWPGPLTMVLPRQPGSTISDLAAAGLPSVAVRVPRGAITTALLRAVGRPVAAPSANLSG
RVSPSDAYHVLRGLSGRIDAVLDSGPCPVGVESTVLDLTGTAPMLLRPGGVTVEALSEVCGPISHPDDYADTLPLSPGRL
ASHYAPGLPVRLDAHDVAADEALLAFGPELPGAGLVWNLSPAGRLDEAAARLFAGLRFLDSEGARRGLVRIAAMPIPRVG
LGMAIRDRLRRAASPRPA

Sequences:

>Translated_338_residues
MIQPNQRLERTGRGVMTERLEANDAGIARAADLLRAGGLVAFGTETVYGLGADATNDTAVARIFAAKERPRFNPLISHFP
DAEAAFAQAAPNDVARRLAERFWPGPLTMVLPRQPGSTISDLAAAGLPSVAVRVPRGAITTALLRAVGRPVAAPSANLSG
RVSPSDAYHVLRGLSGRIDAVLDSGPCPVGVESTVLDLTGTAPMLLRPGGVTVEALSEVCGPISHPDDYADTLPLSPGRL
ASHYAPGLPVRLDAHDVAADEALLAFGPELPGAGLVWNLSPAGRLDEAAARLFAGLRFLDSEGARRGLVRIAAMPIPRVG
LGMAIRDRLRRAASPRPA
>Mature_338_residues
MIQPNQRLERTGRGVMTERLEANDAGIARAADLLRAGGLVAFGTETVYGLGADATNDTAVARIFAAKERPRFNPLISHFP
DAEAAFAQAAPNDVARRLAERFWPGPLTMVLPRQPGSTISDLAAAGLPSVAVRVPRGAITTALLRAVGRPVAAPSANLSG
RVSPSDAYHVLRGLSGRIDAVLDSGPCPVGVESTVLDLTGTAPMLLRPGGVTVEALSEVCGPISHPDDYADTLPLSPGRL
ASHYAPGLPVRLDAHDVAADEALLAFGPELPGAGLVWNLSPAGRLDEAAARLFAGLRFLDSEGARRGLVRIAAMPIPRVG
LGMAIRDRLRRAASPRPA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=137, Percent_Identity=36.4963503649635, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87081864, Length=185, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=181, Percent_Identity=33.1491712707182, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321269, Length=377, Percent_Identity=31.8302387267904, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI78707274, Length=185, Percent_Identity=32.4324324324324, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35270; Mature: 35270

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQPNQRLERTGRGVMTERLEANDAGIARAADLLRAGGLVAFGTETVYGLGADATNDTAV
CCCCHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCEEEECCCCCCCCHHH
ARIFAAKERPRFNPLISHFPDAEAAFAQAAPNDVARRLAERFWPGPLTMVLPRQPGSTIS
HHHHHHHCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHH
DLAAAGLPSVAVRVPRGAITTALLRAVGRPVAAPSANLSGRVSPSDAYHVLRGLSGRIDA
HHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
VLDSGPCPVGVESTVLDLTGTAPMLLRPGGVTVEALSEVCGPISHPDDYADTLPLSPGRL
EECCCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCHH
ASHYAPGLPVRLDAHDVAADEALLAFGPELPGAGLVWNLSPAGRLDEAAARLFAGLRFLD
HHHCCCCCCEEECHHHHHHHCHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
SEGARRGLVRIAAMPIPRVGLGMAIRDRLRRAASPRPA
CCCHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIQPNQRLERTGRGVMTERLEANDAGIARAADLLRAGGLVAFGTETVYGLGADATNDTAV
CCCCHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCEEEECCCCCCCCHHH
ARIFAAKERPRFNPLISHFPDAEAAFAQAAPNDVARRLAERFWPGPLTMVLPRQPGSTIS
HHHHHHHCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHH
DLAAAGLPSVAVRVPRGAITTALLRAVGRPVAAPSANLSGRVSPSDAYHVLRGLSGRIDA
HHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
VLDSGPCPVGVESTVLDLTGTAPMLLRPGGVTVEALSEVCGPISHPDDYADTLPLSPGRL
EECCCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCHH
ASHYAPGLPVRLDAHDVAADEALLAFGPELPGAGLVWNLSPAGRLDEAAARLFAGLRFLD
HHHCCCCCCEEECHHHHHHHCHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
SEGARRGLVRIAAMPIPRVGLGMAIRDRLRRAASPRPA
CCCHHHHHHEEECCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]