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The map label for this gene is cysQ [H]

Identifier: 162149091

GI number: 162149091

Start: 3412101

End: 3412898

Strand: Direct

Name: cysQ [H]

Synonym: GDI_3321

Alternate gene names: 162149091

Gene position: 3412101-3412898 (Clockwise)

Preceding gene: 162149079

Following gene: 162149092

Centisome position: 86.51

GC content: 70.68

Gene sequence:

>798_bases
ATGACGCATTCATCCTCTCTCCTGCAGGCTGGCGACCAGGCGCTGCTGGACCTGGCGACCCGACTGGCCGACGAGGCCGC
CGCCCTGATCCGCGCCATCCGCGCGCGCGGGTTCGAAACCGTCACGAAGTCGGATTCGTCCCCGGTGACCGAAGCCGACC
ACGCCGCCGAGGCTCACATCCTGGCCGGGCTGCGCGCCGCGTTCCCGCACATCCCGGTCATTGCCGAGGAAGAGGCCGCC
GCCGGTATCCGCGTCGCGGGCGGCAAGACGTTCTGGCTGGTCGATCCGCTGGACGGCACGAGGGAATTCGCCGCGGGCCG
CGACGATTTCACCGTCAATATCGGGCTGGTCCGCAACGGCCGCGCCGTGCTGGGCGCGGTCGCCCTTCCGGCCTATCACC
AGCTCTATGCCGCCCATGTCGCCACCGGCGCCATGCGCATCGACGCGGACGGCACCCACGCGATCCATGCCCGCCCGGCA
CCCGGGGAAGGGCTGACGGTGCTGGCGTCGCGCCATTACGCCGACGATCCGCGCCTGGCATCGTTCCTGGGGGGGCACCG
GATCGCGCATCTGGGCAATATCGGGTCCGCCGCGAAGTTCATCCGCGTGGCGGAAGGCGCGGCCGATCTCTACCCCCGGC
TGGGCACGACCATGGAATGGGACACCGCCGCCCCGCAGGCCGTGGTCGAGGCCGCGGGCGGCAGCGTCGCCCTGCTGGAC
GGCACGCCCCTGCGCTACGGGAAGCCCGACTGGCGCAACCCGCATTTTATATGTGCGGGAAAGCGGGAGCATTCATGA

Upstream 100 bases:

>100_bases
AATGCCCCATGCGCGGCCGTCTGTCCAAAACATGCGCCGACACTGCCCGCGCGCGCGAAAGGCGCATGACGCGCGGCGGG
GAGTAAGCTAATGCCAAGGC

Downstream 100 bases:

>100_bases
GCGCACCGCGTTATGATCCAACCGAACCAACGGCTTGAGCGGACGGGCAGAGGAGTCATGACAGAGCGTCTGGAGGCAAA
CGACGCCGGCATCGCCCGGG

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTHSSSLLQAGDQALLDLATRLADEAAALIRAIRARGFETVTKSDSSPVTEADHAAEAHILAGLRAAFPHIPVIAEEEAA
AGIRVAGGKTFWLVDPLDGTREFAAGRDDFTVNIGLVRNGRAVLGAVALPAYHQLYAAHVATGAMRIDADGTHAIHARPA
PGEGLTVLASRHYADDPRLASFLGGHRIAHLGNIGSAAKFIRVAEGAADLYPRLGTTMEWDTAAPQAVVEAAGGSVALLD
GTPLRYGKPDWRNPHFICAGKREHS

Sequences:

>Translated_265_residues
MTHSSSLLQAGDQALLDLATRLADEAAALIRAIRARGFETVTKSDSSPVTEADHAAEAHILAGLRAAFPHIPVIAEEEAA
AGIRVAGGKTFWLVDPLDGTREFAAGRDDFTVNIGLVRNGRAVLGAVALPAYHQLYAAHVATGAMRIDADGTHAIHARPA
PGEGLTVLASRHYADDPRLASFLGGHRIAHLGNIGSAAKFIRVAEGAADLYPRLGTTMEWDTAAPQAVVEAAGGSVALLD
GTPLRYGKPDWRNPHFICAGKREHS
>Mature_264_residues
THSSSLLQAGDQALLDLATRLADEAAALIRAIRARGFETVTKSDSSPVTEADHAAEAHILAGLRAAFPHIPVIAEEEAAA
GIRVAGGKTFWLVDPLDGTREFAAGRDDFTVNIGLVRNGRAVLGAVALPAYHQLYAAHVATGAMRIDADGTHAIHARPAP
GEGLTVLASRHYADDPRLASFLGGHRIAHLGNIGSAAKFIRVAEGAADLYPRLGTTMEWDTAAPQAVVEAAGGSVALLDG
TPLRYGKPDWRNPHFICAGKREHS

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=236, Percent_Identity=30.9322033898305, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=39.4308943089431, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788882, Length=242, Percent_Identity=29.7520661157025, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=272, Percent_Identity=28.6764705882353, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=271, Percent_Identity=28.4132841328413, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71995897, Length=159, Percent_Identity=27.6729559748428, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995905, Length=159, Percent_Identity=27.6729559748428, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357329, Length=237, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24664922, Length=277, Percent_Identity=26.7148014440433, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27851; Mature: 27719

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSSSLLQAGDQALLDLATRLADEAAALIRAIRARGFETVTKSDSSPVTEADHAAEAHI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHH
LAGLRAAFPHIPVIAEEEAAAGIRVAGGKTFWLVDPLDGTREFAAGRDDFTVNIGLVRNG
HHHHHHHCCCCCEEECCCCCCCEEEECCEEEEEECCCCCCHHHHCCCCCEEEEEEEEECC
RAVLGAVALPAYHQLYAAHVATGAMRIDADGTHAIHARPAPGEGLTVLASRHYADDPRLA
CCEEHHHHHHHHHHHHHHHHHHCEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHH
SFLGGHRIAHLGNIGSAAKFIRVAEGAADLYPRLGTTMEWDTAAPQAVVEAAGGSVALLD
HHHCCCCEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEC
GTPLRYGKPDWRNPHFICAGKREHS
CCCCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
THSSSLLQAGDQALLDLATRLADEAAALIRAIRARGFETVTKSDSSPVTEADHAAEAHI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHH
LAGLRAAFPHIPVIAEEEAAAGIRVAGGKTFWLVDPLDGTREFAAGRDDFTVNIGLVRNG
HHHHHHHCCCCCEEECCCCCCCEEEECCEEEEEECCCCCCHHHHCCCCCEEEEEEEEECC
RAVLGAVALPAYHQLYAAHVATGAMRIDADGTHAIHARPAPGEGLTVLASRHYADDPRLA
CCEEHHHHHHHHHHHHHHHHHHCEEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHH
SFLGGHRIAHLGNIGSAAKFIRVAEGAADLYPRLGTTMEWDTAAPQAVVEAAGGSVALLD
HHHCCCCEEECCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEC
GTPLRYGKPDWRNPHFICAGKREHS
CCCCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]