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The map label for this gene is murQ [H]

Identifier: 162148989

GI number: 162148989

Start: 3310961

End: 3311911

Strand: Direct

Name: murQ [H]

Synonym: GDI_3219

Alternate gene names: 162148989

Gene position: 3310961-3311911 (Clockwise)

Preceding gene: 162148988

Following gene: 162148990

Centisome position: 83.95

GC content: 74.55

Gene sequence:

>951_bases
ATGCCCCCCGCCCCGCCGCCGTTCGTTCCCGGGACCGAAGCCTTCAACCCGGCGACCGAGGCCCTGGATACGTGGCCGGT
CCCGGTCCAGGTCGCGACGTTGTGGGAGGGACAGATGAACGCGGTGGCGGCCATCCGTCCGGCACTGGCCGCCATCGCGG
CGGCGGTCGAGGCCGCCCTGCCCCGCCTGCGCGCGGGCGGGCGGCTGGCCTATGCCGGCGCCGGCAGTTCGGGCCGGCTG
GCGGCGCAGGACGGCGCGGAACTGGAACCGACCTTCGACTGGCCCGCCGCGCGCACGATCCTGCTGGTTGCCGGCGGCCC
CCGCGCCCTGACCGAAGCCGTGGAAAACGCCGAGGACGATACCGACGCCGCGCGACGGGACGTCGACGCGGCACGGCTGG
GCCCGGATGACGTGCTGATCGCGCTGGCGGCCAGCGGGCGCACCCCCTACACGCTGGCCTGCGTCGATGCGGCGCGGGCG
GCCGGCGCGCTTGCGATCGGCATCGCCAACAGCGCGGAGGCCCCGCTGCTGGCACGCAGCACCTGCCCGGTCCTGGTCGA
GACCGGGGCCGAGGCCATCGCGGGTTCGACGCGCATGAAGGCCGGCACGGCGCAGAAGATCGTGCTGAACCTGCTGTCCA
CCGCGATGATGATCGGGCTGGGCCGCGTGCATGCCGGCCGGATGGTGGACATGCGCGCGCGCAACGAGAAACTGCGCCAC
CGCGCGGTGCGCATGGTACAGGACGTGACCGGCTGCACGGCACCGGAGGCCGCCGACGCGCTGGCCCGCACCGATGGACG
GGTCAAGCCCGCGATCCTGGTGGCGCTGGGCCTGACGCCGGACGAGGCCGCGGGCGCTCTGGCCCGCCATGACGGCCGCC
TGCGCGGGGCTCTCGGCTCCGTGACGGAAAAATTCCGCCCGGTGCTTGCCAGCGCGCGCAAGGACTCATAG

Upstream 100 bases:

>100_bases
AGGTCCCGCAGGACACCTGGGTGCTGTTCCCCTGGGACACCGCGCCCCTGTTCATCCCGCCCCTGGCCCGCAAGTCCGGC
ACGCCGGGCTGATCCGCCCG

Downstream 100 bases:

>100_bases
CTTCCCCGCAGGTTCGGGGCGTGGCGCAGCCTGGTAGCGCGCGTGTTTTGGGTACACGAGGCCCCCGGTTCGAGTCCGGG
CGCCCCGACCAGCCGGAAGA

Product: sugar isomerase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPPAPPPFVPGTEAFNPATEALDTWPVPVQVATLWEGQMNAVAAIRPALAAIAAAVEAALPRLRAGGRLAYAGAGSSGRL
AAQDGAELEPTFDWPAARTILLVAGGPRALTEAVENAEDDTDAARRDVDAARLGPDDVLIALAASGRTPYTLACVDAARA
AGALAIGIANSAEAPLLARSTCPVLVETGAEAIAGSTRMKAGTAQKIVLNLLSTAMMIGLGRVHAGRMVDMRARNEKLRH
RAVRMVQDVTGCTAPEAADALARTDGRVKPAILVALGLTPDEAAGALARHDGRLRGALGSVTEKFRPVLASARKDS

Sequences:

>Translated_316_residues
MPPAPPPFVPGTEAFNPATEALDTWPVPVQVATLWEGQMNAVAAIRPALAAIAAAVEAALPRLRAGGRLAYAGAGSSGRL
AAQDGAELEPTFDWPAARTILLVAGGPRALTEAVENAEDDTDAARRDVDAARLGPDDVLIALAASGRTPYTLACVDAARA
AGALAIGIANSAEAPLLARSTCPVLVETGAEAIAGSTRMKAGTAQKIVLNLLSTAMMIGLGRVHAGRMVDMRARNEKLRH
RAVRMVQDVTGCTAPEAADALARTDGRVKPAILVALGLTPDEAAGALARHDGRLRGALGSVTEKFRPVLASARKDS
>Mature_315_residues
PPAPPPFVPGTEAFNPATEALDTWPVPVQVATLWEGQMNAVAAIRPALAAIAAAVEAALPRLRAGGRLAYAGAGSSGRLA
AQDGAELEPTFDWPAARTILLVAGGPRALTEAVENAEDDTDAARRDVDAARLGPDDVLIALAASGRTPYTLACVDAARAA
GALAIGIANSAEAPLLARSTCPVLVETGAEAIAGSTRMKAGTAQKIVLNLLSTAMMIGLGRVHAGRMVDMRARNEKLRHR
AVRMVQDVTGCTAPEAADALARTDGRVKPAILVALGLTPDEAAGALARHDGRLRGALGSVTEKFRPVLASARKDS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=291, Percent_Identity=38.8316151202749, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32445; Mature: 32314

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAPPPFVPGTEAFNPATEALDTWPVPVQVATLWEGQMNAVAAIRPALAAIAAAVEAAL
CCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
PRLRAGGRLAYAGAGSSGRLAAQDGAELEPTFDWPAARTILLVAGGPRALTEAVENAEDD
HHHCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCH
TDAARRDVDAARLGPDDVLIALAASGRTPYTLACVDAARAAGALAIGIANSAEAPLLARS
HHHHHHCCCHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHCCEEEEEECCCCCCCEEECC
TCPVLVETGAEAIAGSTRMKAGTAQKIVLNLLSTAMMIGLGRVHAGRMVDMRARNEKLRH
CCCEEEECCCHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
RAVRMVQDVTGCTAPEAADALARTDGRVKPAILVALGLTPDEAAGALARHDGRLRGALGS
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHH
VTEKFRPVLASARKDS
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPAPPPFVPGTEAFNPATEALDTWPVPVQVATLWEGQMNAVAAIRPALAAIAAAVEAAL
CCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
PRLRAGGRLAYAGAGSSGRLAAQDGAELEPTFDWPAARTILLVAGGPRALTEAVENAEDD
HHHCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCH
TDAARRDVDAARLGPDDVLIALAASGRTPYTLACVDAARAAGALAIGIANSAEAPLLARS
HHHHHHCCCHHHCCCCCEEEEEECCCCCCEEEEEHHHHHHCCEEEEEECCCCCCCEEECC
TCPVLVETGAEAIAGSTRMKAGTAQKIVLNLLSTAMMIGLGRVHAGRMVDMRARNEKLRH
CCCEEEECCCHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
RAVRMVQDVTGCTAPEAADALARTDGRVKPAILVALGLTPDEAAGALARHDGRLRGALGS
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHH
VTEKFRPVLASARKDS
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]