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The map label for this gene is gpt [H]

Identifier: 162148988

GI number: 162148988

Start: 3310446

End: 3310952

Strand: Direct

Name: gpt [H]

Synonym: GDI_3218

Alternate gene names: 162148988

Gene position: 3310446-3310952 (Clockwise)

Preceding gene: 162148987

Following gene: 162148989

Centisome position: 83.93

GC content: 68.84

Gene sequence:

>507_bases
ATGCAACCGTCACCTGGGACCAGGTTCACCGCCAACTACGCAACCGTCACCTGGGACCAGCTTCACCGCGACGCCCGCCT
GCTGGCCGAAACCCTGATCCCGCGCGGGCCGTTCAAGGGCATCGTGGCGGTCACGCGCGGGGGCCTGATCCCGGCCGCCA
TCATCGCCCGCGAAATCGACTGCCGCCTGATCGAAACGATCTCGGTCGTGACGTACGACGAGGAAGAACAGGGCAAGCCC
ACCGTCCTGAAGGCCCCGGCGGCCGCGGGTGACGGCGAGGGCTTCCTGATCATCGACGACCTGGTCGATTCCGGCGTGAC
GGCACAGATCGTGCGCCAGCTCCTGCCCAAGGCGCTGTTAGCCTGCCTGTACGCCAAGCCGTCGGGCCGGCCGCTGACCG
ACCTGTTCGTGGTCGAGGTCCCGCAGGACACCTGGGTGCTGTTCCCCTGGGACACCGCGCCCCTGTTCATCCCGCCCCTG
GCCCGCAAGTCCGGCACGCCGGGCTGA

Upstream 100 bases:

>100_bases
CCTGACCCTGGGCATGCCCGACGCAAGGGGCGACGTCGTCCTGATCAAACCCGACCTGACCGTGCCTGACGGAGGAAAGC
TGTTCTGATGGCCACCAACT

Downstream 100 bases:

>100_bases
TCCGCCCGATGCCCCCCGCCCCGCCGCCGTTCGTTCCCGGGACCGAAGCCTTCAACCCGGCGACCGAGGCCCTGGATACG
TGGCCGGTCCCGGTCCAGGT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MQPSPGTRFTANYATVTWDQLHRDARLLAETLIPRGPFKGIVAVTRGGLIPAAIIAREIDCRLIETISVVTYDEEEQGKP
TVLKAPAAAGDGEGFLIIDDLVDSGVTAQIVRQLLPKALLACLYAKPSGRPLTDLFVVEVPQDTWVLFPWDTAPLFIPPL
ARKSGTPG

Sequences:

>Translated_168_residues
MQPSPGTRFTANYATVTWDQLHRDARLLAETLIPRGPFKGIVAVTRGGLIPAAIIAREIDCRLIETISVVTYDEEEQGKP
TVLKAPAAAGDGEGFLIIDDLVDSGVTAQIVRQLLPKALLACLYAKPSGRPLTDLFVVEVPQDTWVLFPWDTAPLFIPPL
ARKSGTPG
>Mature_168_residues
MQPSPGTRFTANYATVTWDQLHRDARLLAETLIPRGPFKGIVAVTRGGLIPAAIIAREIDCRLIETISVVTYDEEEQGKP
TVLKAPAAAGDGEGFLIIDDLVDSGVTAQIVRQLLPKALLACLYAKPSGRPLTDLFVVEVPQDTWVLFPWDTAPLFIPPL
ARKSGTPG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786433, Length=146, Percent_Identity=50.6849315068493, Blast_Score=160, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 18159; Mature: 18159

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER ; PS00247 HBGF_FGF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSPGTRFTANYATVTWDQLHRDARLLAETLIPRGPFKGIVAVTRGGLIPAAIIAREID
CCCCCCCEEEECEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCC
CRLIETISVVTYDEEEQGKPTVLKAPAAAGDGEGFLIIDDLVDSGVTAQIVRQLLPKALL
CEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHH
ACLYAKPSGRPLTDLFVVEVPQDTWVLFPWDTAPLFIPPLARKSGTPG
HHHHCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MQPSPGTRFTANYATVTWDQLHRDARLLAETLIPRGPFKGIVAVTRGGLIPAAIIAREID
CCCCCCCEEEECEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCC
CRLIETISVVTYDEEEQGKPTVLKAPAAAGDGEGFLIIDDLVDSGVTAQIVRQLLPKALL
CEEEEEEEEEEECCCCCCCCCEEECCCCCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHH
ACLYAKPSGRPLTDLFVVEVPQDTWVLFPWDTAPLFIPPLARKSGTPG
HHHHCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA