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The map label for this gene is ytfL [H]

Identifier: 162148972

GI number: 162148972

Start: 3294405

End: 3295742

Strand: Direct

Name: ytfL [H]

Synonym: GDI_3202

Alternate gene names: 162148972

Gene position: 3294405-3295742 (Clockwise)

Preceding gene: 162148971

Following gene: 162148978

Centisome position: 83.53

GC content: 68.16

Gene sequence:

>1338_bases
GTGATTCTTCTGGCCGGCCTGATCGCCATCATCGCGCTGATCGCCGTCAGCATCCTGATCTCGCTGTCGGAAATCTCGTT
CGCCGCCGCGCGTGATGTCAGGCTGCGCACCCGGGCCGAGGCCGGGGACACCAGGGCGGTGAATTTCCTGCGCCTGCGCC
GCAACAGCGGGCAGGTCATCACGGTGCTGCAGATCTGCCTGAACGCCGTCGGCGTGCTGGGCGGCGTCATCAGCAGCGAA
CTGATCACCCCGCCCCTGGCGCTGATCCTGCATTCGGCCGGCCTGGCGGCGGGGCTGGCGGCGGACGTGGCCTCCACCGC
GTCCTTCCTGCTGGTGACGGGCCTGTTCGTGCTGTTCGCCGACCTGCTGCCCAAGCGGATCGCGATGAACGCGCCGGACC
GCGTGGCGCTGGCCATCGGCTGGTTCCCCGCCATCGCCCTGCGGGTGCTGTTTCCCGCCGTCTGGATCTTCTCGAAAATC
TCCGACGTCATCCTGCGCGCGCTGAGGATCCCGGCGGCCTCGGCCGTGGAACCGGTCACGCCCGAGGACCTGCGCGCGAT
CCTGGCCGCCGGCACCGCATCGGGAATCCTGCTGGAGCAGGAACACCAGATGATCCAGAACGTCCTGGGGTTGCAGGACC
GGTCCGTGACCTCGGCCATGACCCCGCGCGACGAAATCGTCTTCCTCGACGTGCAGGAAAGCACCGAGAGCCAGCGCGAC
AAGGTCCGCGCCAAGCCCTATTCGCGCTATCCGCTGTGCAATGGCGGGCTGGACAACGTCATCGGCTCGATCCGCGCCGA
GGACGTGCTGGCCGCCGTGGTCGAGGACGCGCCGACCGCCACCCCCGGCACGGTCCTGCCGGCCGCGCGCCAGATCTCGC
GCATGCGGCGCGACGTGCTGTCGCTGCCCGATACGCTGAATCTGTGGGACACGCTGGCCCAGTTCGACACGCACGGCGCG
GGCTTCGCGCTGATCGTGAACGAATACGGGCTGGTGGTCGGGCTGATCACGTTCAAGGACATCATGGGCGCGCTGATGGA
CGGCTTGGCCAACCCGTTCGAGGAACAGGCCATCGTGCGCCGCGACGAAAATTCGTGGCTGATCGACGGCGCGGCCCCGA
TCGGCGACGTGATCCGCGAACTCGGGATCGCGACGCTGCCCGACAGCCACAATTTCGATACGATCGGCGGCTTCATCATG
CACCGCCTGCGCCGCATGGCCCGCAAGGCCGACCGCGTCGAGGCCGCGAACTTCCTGTTCGAAGTGGTCGACGTCGAAGG
CTTCCGCATCAATCAGCTCCTGGTCACGCGGCGCCCGAGGCGCGCCGAGGCCGACTGA

Upstream 100 bases:

>100_bases
GCATGAAATATTCTGTCGCCGGGGCCAGCCGTCCCCTTCCCCCGTCCGGGCCTGCCGCGCCGTGCGGGATGCATCGTGAC
GCGCGCGTAGGGGGCCGGTC

Downstream 100 bases:

>100_bases
ATCCTGTCCGGAAAGACGCTTATCCTATCTAAAAATATGATTGATCCCGGCAAGTCGAATGCCATCGCGTCGAATACGTT
GCTGACGTGACAGGGAATAT

Product: transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MILLAGLIAIIALIAVSILISLSEISFAAARDVRLRTRAEAGDTRAVNFLRLRRNSGQVITVLQICLNAVGVLGGVISSE
LITPPLALILHSAGLAAGLAADVASTASFLLVTGLFVLFADLLPKRIAMNAPDRVALAIGWFPAIALRVLFPAVWIFSKI
SDVILRALRIPAASAVEPVTPEDLRAILAAGTASGILLEQEHQMIQNVLGLQDRSVTSAMTPRDEIVFLDVQESTESQRD
KVRAKPYSRYPLCNGGLDNVIGSIRAEDVLAAVVEDAPTATPGTVLPAARQISRMRRDVLSLPDTLNLWDTLAQFDTHGA
GFALIVNEYGLVVGLITFKDIMGALMDGLANPFEEQAIVRRDENSWLIDGAAPIGDVIRELGIATLPDSHNFDTIGGFIM
HRLRRMARKADRVEAANFLFEVVDVEGFRINQLLVTRRPRRAEAD

Sequences:

>Translated_445_residues
MILLAGLIAIIALIAVSILISLSEISFAAARDVRLRTRAEAGDTRAVNFLRLRRNSGQVITVLQICLNAVGVLGGVISSE
LITPPLALILHSAGLAAGLAADVASTASFLLVTGLFVLFADLLPKRIAMNAPDRVALAIGWFPAIALRVLFPAVWIFSKI
SDVILRALRIPAASAVEPVTPEDLRAILAAGTASGILLEQEHQMIQNVLGLQDRSVTSAMTPRDEIVFLDVQESTESQRD
KVRAKPYSRYPLCNGGLDNVIGSIRAEDVLAAVVEDAPTATPGTVLPAARQISRMRRDVLSLPDTLNLWDTLAQFDTHGA
GFALIVNEYGLVVGLITFKDIMGALMDGLANPFEEQAIVRRDENSWLIDGAAPIGDVIRELGIATLPDSHNFDTIGGFIM
HRLRRMARKADRVEAANFLFEVVDVEGFRINQLLVTRRPRRAEAD
>Mature_445_residues
MILLAGLIAIIALIAVSILISLSEISFAAARDVRLRTRAEAGDTRAVNFLRLRRNSGQVITVLQICLNAVGVLGGVISSE
LITPPLALILHSAGLAAGLAADVASTASFLLVTGLFVLFADLLPKRIAMNAPDRVALAIGWFPAIALRVLFPAVWIFSKI
SDVILRALRIPAASAVEPVTPEDLRAILAAGTASGILLEQEHQMIQNVLGLQDRSVTSAMTPRDEIVFLDVQESTESQRD
KVRAKPYSRYPLCNGGLDNVIGSIRAEDVLAAVVEDAPTATPGTVLPAARQISRMRRDVLSLPDTLNLWDTLAQFDTHGA
GFALIVNEYGLVVGLITFKDIMGALMDGLANPFEEQAIVRRDENSWLIDGAAPIGDVIRELGIATLPDSHNFDTIGGFIM
HRLRRMARKADRVEAANFLFEVVDVEGFRINQLLVTRRPRRAEAD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=385, Percent_Identity=22.0779220779221, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1790664, Length=442, Percent_Identity=42.3076923076923, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI145693175, Length=417, Percent_Identity=23.9808153477218, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082033, Length=251, Percent_Identity=25.8964143426295, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788119, Length=251, Percent_Identity=25.4980079681275, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786879, Length=262, Percent_Identity=22.1374045801527, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48113; Mature: 48113

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLAGLIAIIALIAVSILISLSEISFAAARDVRLRTRAEAGDTRAVNFLRLRRNSGQVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCCH
TVLQICLNAVGVLGGVISSELITPPLALILHSAGLAAGLAADVASTASFLLVTGLFVLFA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLPKRIAMNAPDRVALAIGWFPAIALRVLFPAVWIFSKISDVILRALRIPAASAVEPVT
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PEDLRAILAAGTASGILLEQEHQMIQNVLGLQDRSVTSAMTPRDEIVFLDVQESTESQRD
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEEEHHHHHHHHH
KVRAKPYSRYPLCNGGLDNVIGSIRAEDVLAAVVEDAPTATPGTVLPAARQISRMRRDVL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
SLPDTLNLWDTLAQFDTHGAGFALIVNEYGLVVGLITFKDIMGALMDGLANPFEEQAIVR
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHE
RDENSWLIDGAAPIGDVIRELGIATLPDSHNFDTIGGFIMHRLRRMARKADRVEAANFLF
ECCCCEEEECCCCHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVDVEGFRINQLLVTRRPRRAEAD
HHHCCCCEEEHHHHHCCCCCCCCCC
>Mature Secondary Structure
MILLAGLIAIIALIAVSILISLSEISFAAARDVRLRTRAEAGDTRAVNFLRLRRNSGQVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCCH
TVLQICLNAVGVLGGVISSELITPPLALILHSAGLAAGLAADVASTASFLLVTGLFVLFA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLPKRIAMNAPDRVALAIGWFPAIALRVLFPAVWIFSKISDVILRALRIPAASAVEPVT
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PEDLRAILAAGTASGILLEQEHQMIQNVLGLQDRSVTSAMTPRDEIVFLDVQESTESQRD
HHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEEEHHHHHHHHH
KVRAKPYSRYPLCNGGLDNVIGSIRAEDVLAAVVEDAPTATPGTVLPAARQISRMRRDVL
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
SLPDTLNLWDTLAQFDTHGAGFALIVNEYGLVVGLITFKDIMGALMDGLANPFEEQAIVR
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHE
RDENSWLIDGAAPIGDVIRELGIATLPDSHNFDTIGGFIMHRLRRMARKADRVEAANFLF
ECCCCEEEECCCCHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVVDVEGFRINQLLVTRRPRRAEAD
HHHCCCCEEEHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]