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The map label for this gene is sufC [H]

Identifier: 162148829

GI number: 162148829

Start: 3151524

End: 3152240

Strand: Reverse

Name: sufC [H]

Synonym: GDI_3058

Alternate gene names: 162148829

Gene position: 3152240-3151524 (Counterclockwise)

Preceding gene: 162148830

Following gene: 162148828

Centisome position: 79.92

GC content: 66.67

Gene sequence:

>717_bases
GTGGAGAAGGAGATCCTGCGCGGCGTCGATCTCGACATCCCCGCGGGCGAGGTCCACGCGATCATGGGGCCCAACGGGTC
GGGCAAGTCCACGCTGTCCTATGTCCTGGCCGGGCGAGAGGATTACGAGGTGACGGCCGGCACCGCGACCTTCAAGGGCC
AGGACCTGCTGGCGCTGGACCCCGAGGCGCGCGCGGCGCTGGGCCTGTTCCTGGCCTTCCAGGCGCCGGTCGAACTGCCC
GGCGTGAACAACGCGAATTTCCTGCGCACGGCGGTCAACGCGGTGCGTCGCGCCCGGGGCCAGGACGAACTGGACGCGGT
GGCCTTCCTGAAGGCGGTGCGCAAGGAAACCAAGCATCTGTCGATGTCTGACGACATGCTGAAGCGCAACGTGAATGTGG
GCTTTTCGGGCGGCGAGAAGAAGCGCAACGAAGTGCTGCAGATGCGCATGCTGCAGCCCTCCTTCGCCATTCTGGACGAA
ACCGACAGCGGACTGGACATCGATGCGCTGCGCATCGTGGCCGAAGGCGTCAATTCGCTGCGCGCGCCCGATTTCTCGGC
CCTGGTCATCACCCATCACCAGCGCCTGCTGGACTATATCGTCCCGGACCGCATCCATGTGATGGCGCGCGGGCGCATCA
TCCACAGCGGCGGTCCCGAACTGGCGAAGCAGCTCGAGGCCCAGGGCTATGCCCGCTTCCTGGCGGAGGCCGCGTGA

Upstream 100 bases:

>100_bases
GATCAGCCTGGAAGGCAGCGTCGGCTGAACGGAGATGAGTGACGTGAGCAACGAGTTTGTACGGATCGCCGGCCTGTGCG
CCAGAATTTCGGATGGCGGA

Downstream 100 bases:

>100_bases
ACGCGGTCGCCGAGAACGCGGTCGCCCGGGGGGGCAGGACCGCCGGCGCCAGCGCCGCGTCCTTCCTGGCCCGGTATGAC
GGGCAGGCGGGCGCGAACCC

Product: FeS assembly protein SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEKEILRGVDLDIPAGEVHAIMGPNGSGKSTLSYVLAGREDYEVTAGTATFKGQDLLALDPEARAALGLFLAFQAPVELP
GVNNANFLRTAVNAVRRARGQDELDAVAFLKAVRKETKHLSMSDDMLKRNVNVGFSGGEKKRNEVLQMRMLQPSFAILDE
TDSGLDIDALRIVAEGVNSLRAPDFSALVITHHQRLLDYIVPDRIHVMARGRIIHSGGPELAKQLEAQGYARFLAEAA

Sequences:

>Translated_238_residues
MEKEILRGVDLDIPAGEVHAIMGPNGSGKSTLSYVLAGREDYEVTAGTATFKGQDLLALDPEARAALGLFLAFQAPVELP
GVNNANFLRTAVNAVRRARGQDELDAVAFLKAVRKETKHLSMSDDMLKRNVNVGFSGGEKKRNEVLQMRMLQPSFAILDE
TDSGLDIDALRIVAEGVNSLRAPDFSALVITHHQRLLDYIVPDRIHVMARGRIIHSGGPELAKQLEAQGYARFLAEAA
>Mature_238_residues
MEKEILRGVDLDIPAGEVHAIMGPNGSGKSTLSYVLAGREDYEVTAGTATFKGQDLLALDPEARAALGLFLAFQAPVELP
GVNNANFLRTAVNAVRRARGQDELDAVAFLKAVRKETKHLSMSDDMLKRNVNVGFSGGEKKRNEVLQMRMLQPSFAILDE
TDSGLDIDALRIVAEGVNSLRAPDFSALVITHHQRLLDYIVPDRIHVMARGRIIHSGGPELAKQLEAQGYARFLAEAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=223, Percent_Identity=31.390134529148, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787972, Length=235, Percent_Identity=62.5531914893617, Blast_Score=300, Evalue=5e-83,
Organism=Escherichia coli, GI1788761, Length=235, Percent_Identity=28.936170212766, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87081709, Length=235, Percent_Identity=25.1063829787234, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786319, Length=189, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790525, Length=215, Percent_Identity=27.4418604651163, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789864, Length=227, Percent_Identity=24.6696035242291, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789593, Length=225, Percent_Identity=23.5555555555556, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=225, Percent_Identity=31.1111111111111, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=228, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357907, Length=225, Percent_Identity=29.3333333333333, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 25901; Mature: 25901

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEILRGVDLDIPAGEVHAIMGPNGSGKSTLSYVLAGREDYEVTAGTATFKGQDLLALD
CCCHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEECCEEEECCCEEEEEC
PEARAALGLFLAFQAPVELPGVNNANFLRTAVNAVRRARGQDELDAVAFLKAVRKETKHL
CHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SMSDDMLKRNVNVGFSGGEKKRNEVLQMRMLQPSFAILDETDSGLDIDALRIVAEGVNSL
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RAPDFSALVITHHQRLLDYIVPDRIHVMARGRIIHSGGPELAKQLEAQGYARFLAEAA
CCCCCEEEEHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKEILRGVDLDIPAGEVHAIMGPNGSGKSTLSYVLAGREDYEVTAGTATFKGQDLLALD
CCCHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEECCEEEECCCEEEEEC
PEARAALGLFLAFQAPVELPGVNNANFLRTAVNAVRRARGQDELDAVAFLKAVRKETKHL
CHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SMSDDMLKRNVNVGFSGGEKKRNEVLQMRMLQPSFAILDETDSGLDIDALRIVAEGVNSL
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RAPDFSALVITHHQRLLDYIVPDRIHVMARGRIIHSGGPELAKQLEAQGYARFLAEAA
CCCCCEEEEHHHHHHHHHHHCCCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]