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The map label for this gene is nouH [H]

Identifier: 162148804

GI number: 162148804

Start: 3123569

End: 3124594

Strand: Reverse

Name: nouH [H]

Synonym: GDI_3033

Alternate gene names: 162148804

Gene position: 3124594-3123569 (Counterclockwise)

Preceding gene: 162148805

Following gene: 162148803

Centisome position: 79.22

GC content: 63.84

Gene sequence:

>1026_bases
GTGGCGCATTTCTTTCTGCACACCCTGATCGGTCAGGTGATCCTGACGGTCCTCGAGGCCCTGGCCGTGCTGGTGCCGCT
GCTGCTGGGGGTCGCCTACCTGACCCTCGGGGAACGCAAGGTCATGGCGGCGATGCAGCTCCGCAAGGGGCCGAACGTGA
ACGGCCCGTTCGGCGTGCTGCAGGCCTTTGCCGACGCGATCAAGATGATCACCAAGGAAACGGTGATCCCGTCCGGGGCC
AACCGGTTCCTGTTCCTGTTCGCACCGTTCCTGACCTTCTCGCTGGCCATGGTCGCCTGGGCGGTCATTCCCACCAATAA
CGGCTGGGCGATAGCGAACATCAATGTCGGGATACTCTACCTGCTCGCGATTTCCTCGCTGGGGGTCTACGGCATCCTGA
TCGCGGGCTGGGCGTCCAACTCCAAATACGCCTTCCTGGGCGGCCTGCGCTCGGCGGCGCAGATGGTGTCCTACGAGGTC
TCGATCGGCCTGGTCATCGTCTCGGTCCTGCTGGCGGTCGGCAGCCTGAACCTGAACGACATCGTCCTCGCGCAGCGCCA
TGTCTGGTTCTGCCTGCCGATGTTCCCGATGTTCATCGTCTTCTTCATCTCGGCGCTGGCGGAAACCAACCGCGCGCCGT
TCGACCTGCCCGAGGGCGAGAGTGAACTGGTGGCCGGCTTCTTCGTCGAATATTCGGCGCTGGCCTTCGGTCTCTTCTTC
CTGGGCGAATACGCCAACATGTTCCTGATGTCGGGGATGGTCAGCATCCTGTTCCTGGGCGGCTGGCTGCCGCCGGTGGG
GATCGCGCCCTTCACCTGGATCCCGGGGCCGCTGTGGCTGATCGCGAAGATCCTGTTCTGCCTGTTCGTCTTCATCTGGG
TGCGCGCGACATTCCCGCGCTACCGCTACGACCAGCTGATGCGGCTGGGATGGAAGGTGTTCCTTCCGTTCTCGCTGGTG
TGGATGGTGCTGACGGCGGGCTTCCTGCTGGCGACCGGGCTTCTGCCCCAGGGAGGAGCAAGCTGA

Upstream 100 bases:

>100_bases
TTATTACCAGACGAATCCGATCTGCCGGGCCAGTCCGACGATGGGCGAATGTTCGCGGATCTATGTCCCCCCCCGGGCCC
TGGCGGCGGAGTAAGGCGAC

Downstream 100 bases:

>100_bases
TGGGACATTTCGACCGGACGGTCCGTTCCTTCCTTCTGGCCGAGCTCGTGGCCGGAATGGGGGCCACGTTCAAGGCCATG
TTCAAGCCCAAGGTGACGAT

Product: NADH-quinone oxidoreductase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAHFFLHTLIGQVILTVLEALAVLVPLLLGVAYLTLGERKVMAAMQLRKGPNVNGPFGVLQAFADAIKMITKETVIPSGA
NRFLFLFAPFLTFSLAMVAWAVIPTNNGWAIANINVGILYLLAISSLGVYGILIAGWASNSKYAFLGGLRSAAQMVSYEV
SIGLVIVSVLLAVGSLNLNDIVLAQRHVWFCLPMFPMFIVFFISALAETNRAPFDLPEGESELVAGFFVEYSALAFGLFF
LGEYANMFLMSGMVSILFLGGWLPPVGIAPFTWIPGPLWLIAKILFCLFVFIWVRATFPRYRYDQLMRLGWKVFLPFSLV
WMVLTAGFLLATGLLPQGGAS

Sequences:

>Translated_341_residues
MAHFFLHTLIGQVILTVLEALAVLVPLLLGVAYLTLGERKVMAAMQLRKGPNVNGPFGVLQAFADAIKMITKETVIPSGA
NRFLFLFAPFLTFSLAMVAWAVIPTNNGWAIANINVGILYLLAISSLGVYGILIAGWASNSKYAFLGGLRSAAQMVSYEV
SIGLVIVSVLLAVGSLNLNDIVLAQRHVWFCLPMFPMFIVFFISALAETNRAPFDLPEGESELVAGFFVEYSALAFGLFF
LGEYANMFLMSGMVSILFLGGWLPPVGIAPFTWIPGPLWLIAKILFCLFVFIWVRATFPRYRYDQLMRLGWKVFLPFSLV
WMVLTAGFLLATGLLPQGGAS
>Mature_340_residues
AHFFLHTLIGQVILTVLEALAVLVPLLLGVAYLTLGERKVMAAMQLRKGPNVNGPFGVLQAFADAIKMITKETVIPSGAN
RFLFLFAPFLTFSLAMVAWAVIPTNNGWAIANINVGILYLLAISSLGVYGILIAGWASNSKYAFLGGLRSAAQMVSYEVS
IGLVIVSVLLAVGSLNLNDIVLAQRHVWFCLPMFPMFIVFFISALAETNRAPFDLPEGESELVAGFFVEYSALAFGLFFL
GEYANMFLMSGMVSILFLGGWLPPVGIAPFTWIPGPLWLIAKILFCLFVFIWVRATFPRYRYDQLMRLGWKVFLPFSLVW
MVLTAGFLLATGLLPQGGAS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=290, Percent_Identity=47.2413793103448, Blast_Score=265, Evalue=3e-71,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=42.3197492163009, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI1789077, Length=300, Percent_Identity=27, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37368; Mature: 37237

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFFLHTLIGQVILTVLEALAVLVPLLLGVAYLTLGERKVMAAMQLRKGPNVNGPFGVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHH
QAFADAIKMITKETVIPSGANRFLFLFAPFLTFSLAMVAWAVIPTNNGWAIANINVGILY
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHH
LLAISSLGVYGILIAGWASNSKYAFLGGLRSAAQMVSYEVSIGLVIVSVLLAVGSLNLND
HHHHHHCCHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IVLAQRHVWFCLPMFPMFIVFFISALAETNRAPFDLPEGESELVAGFFVEYSALAFGLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGEYANMFLMSGMVSILFLGGWLPPVGIAPFTWIPGPLWLIAKILFCLFVFIWVRATFPR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
YRYDQLMRLGWKVFLPFSLVWMVLTAGFLLATGLLPQGGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AHFFLHTLIGQVILTVLEALAVLVPLLLGVAYLTLGERKVMAAMQLRKGPNVNGPFGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHH
QAFADAIKMITKETVIPSGANRFLFLFAPFLTFSLAMVAWAVIPTNNGWAIANINVGILY
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCHHHHH
LLAISSLGVYGILIAGWASNSKYAFLGGLRSAAQMVSYEVSIGLVIVSVLLAVGSLNLND
HHHHHHCCHHHHHEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IVLAQRHVWFCLPMFPMFIVFFISALAETNRAPFDLPEGESELVAGFFVEYSALAFGLFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGEYANMFLMSGMVSILFLGGWLPPVGIAPFTWIPGPLWLIAKILFCLFVFIWVRATFPR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
YRYDQLMRLGWKVFLPFSLVWMVLTAGFLLATGLLPQGGAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA