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The map label for this gene is tktB [C]

Identifier: 162148782

GI number: 162148782

Start: 3097437

End: 3098189

Strand: Reverse

Name: tktB [C]

Synonym: GDI_3011

Alternate gene names: 162148782

Gene position: 3098189-3097437 (Counterclockwise)

Preceding gene: 162148783

Following gene: 162148781

Centisome position: 78.55

GC content: 57.24

Gene sequence:

>753_bases
ATGGTCGAAATCCTGAACACGCTCTTCAGTGAAATACTCGTTCATCGCCCCCATGAGCCCGAGTGGAACGATCGGGATGT
ATTCATCCTCAGCAAGGGCCACGCGGTTTTAGGCTACTTTGCCGTGCTTCATCGCCAGGGATATTTTTCGGCCGAAAAGC
TCGCGACCTTCCAGACGAACGGCAGCGACCTGATCGCACACCCTGTCAAAAAAGAGGTACTGGGCATCGAAAGCTCCAAT
GGCAGCCTCGGGCAGGGCCTCGCTTATGGCATGGGCATGGCGCTGGGCATGCGCAAGCGCGGGCAGGACAGGCGTGTCTA
CGTCATGCTGGGCGACGGCGAGTGCAATGAAGGCTCCGTTTGGGAAAGCGCCGCCACGGCTGCGGAGTTGGGTCTCGGAA
ACCTGACGGCGATTATCGATGAGAACGGCTTCCGAAATGACGGTCCCAATACGACGTACGCGGGCAGGGTCGTGCTGGCG
AATGTGTGGAGGGCATTTGGCTGGAACGTGATCGAAATCGACGGGCATGACCATCAGGTCATCCTGAATGCTTTCCAGAA
TGCGCGGCATACCACGGACACGCCTACGGCGATTGTGGCGCGTACGGTGAAGGGCAGGGGCGTGGACTTTATGGAGAACA
ATAACGATTGGCATCATAATCGCATCACGGCCAACGTTTTCGAAAGATGTCTGAAGGTTCTGGACGGTTGCGATCTGCCG
AAGCTTGATGCGTCAGGAGAGCCGAGTGTCTGA

Upstream 100 bases:

>100_bases
AGACCTGAGCTTCGCTGAAGCCTGCCTGGAAGTCCGCCGTACAATTATTGAGACTGCCTTCAAATGCGGACAGGCGACGC
ATATTGGTGGCAGTCTAAGT

Downstream 100 bases:

>100_bases
AATTTCGAATTCCAGCGCCCGCGCACTGGCGCGCCTGGGGCCAAGGGCCACCTATGGCCAGACGCTGACCACCCTGGCGG
GTGCCGACAGAAATATCATC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MVEILNTLFSEILVHRPHEPEWNDRDVFILSKGHAVLGYFAVLHRQGYFSAEKLATFQTNGSDLIAHPVKKEVLGIESSN
GSLGQGLAYGMGMALGMRKRGQDRRVYVMLGDGECNEGSVWESAATAAELGLGNLTAIIDENGFRNDGPNTTYAGRVVLA
NVWRAFGWNVIEIDGHDHQVILNAFQNARHTTDTPTAIVARTVKGRGVDFMENNNDWHHNRITANVFERCLKVLDGCDLP
KLDASGEPSV

Sequences:

>Translated_250_residues
MVEILNTLFSEILVHRPHEPEWNDRDVFILSKGHAVLGYFAVLHRQGYFSAEKLATFQTNGSDLIAHPVKKEVLGIESSN
GSLGQGLAYGMGMALGMRKRGQDRRVYVMLGDGECNEGSVWESAATAAELGLGNLTAIIDENGFRNDGPNTTYAGRVVLA
NVWRAFGWNVIEIDGHDHQVILNAFQNARHTTDTPTAIVARTVKGRGVDFMENNNDWHHNRITANVFERCLKVLDGCDLP
KLDASGEPSV
>Mature_250_residues
MVEILNTLFSEILVHRPHEPEWNDRDVFILSKGHAVLGYFAVLHRQGYFSAEKLATFQTNGSDLIAHPVKKEVLGIESSN
GSLGQGLAYGMGMALGMRKRGQDRRVYVMLGDGECNEGSVWESAATAAELGLGNLTAIIDENGFRNDGPNTTYAGRVVLA
NVWRAFGWNVIEIDGHDHQVILNAFQNARHTTDTPTAIVARTVKGRGVDFMENNNDWHHNRITANVFERCLKVLDGCDLP
KLDASGEPSV

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=234, Percent_Identity=36.3247863247863, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI205277463, Length=231, Percent_Identity=37.2294372294372, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI4507521, Length=231, Percent_Identity=37.2294372294372, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI225637461, Length=239, Percent_Identity=29.7071129707113, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI225637459, Length=239, Percent_Identity=29.7071129707113, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI225637463, Length=237, Percent_Identity=29.1139240506329, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1788808, Length=219, Percent_Identity=37.4429223744292, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI48994911, Length=230, Percent_Identity=34.3478260869565, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17539652, Length=223, Percent_Identity=38.5650224215247, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=220, Percent_Identity=35.4545454545455, Blast_Score=112, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319593, Length=220, Percent_Identity=30.4545454545455, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45551847, Length=219, Percent_Identity=37.8995433789954, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI45550715, Length=219, Percent_Identity=37.8995433789954, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24645119, Length=215, Percent_Identity=37.6744186046512, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24666278, Length=223, Percent_Identity=35.8744394618834, Blast_Score=120, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 27545; Mature: 27545

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEILNTLFSEILVHRPHEPEWNDRDVFILSKGHAVLGYFAVLHRQGYFSAEKLATFQTN
CHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHEEEEECC
GSDLIAHPVKKEVLGIESSNGSLGQGLAYGMGMALGMRKRGQDRRVYVMLGDGECNEGSV
CCCEECCHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
WESAATAAELGLGNLTAIIDENGFRNDGPNTTYAGRVVLANVWRAFGWNVIEIDGHDHQV
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHH
ILNAFQNARHTTDTPTAIVARTVKGRGVDFMENNNDWHHNRITANVFERCLKVLDGCDLP
HHHHHHCCCCCCCCCHHHEEEHHCCCCCCEEECCCCCCCCCEEHHHHHHHHHHHCCCCCC
KLDASGEPSV
CCCCCCCCCC
>Mature Secondary Structure
MVEILNTLFSEILVHRPHEPEWNDRDVFILSKGHAVLGYFAVLHRQGYFSAEKLATFQTN
CHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHEEEEECC
GSDLIAHPVKKEVLGIESSNGSLGQGLAYGMGMALGMRKRGQDRRVYVMLGDGECNEGSV
CCCEECCHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
WESAATAAELGLGNLTAIIDENGFRNDGPNTTYAGRVVLANVWRAFGWNVIEIDGHDHQV
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHH
ILNAFQNARHTTDTPTAIVARTVKGRGVDFMENNNDWHHNRITANVFERCLKVLDGCDLP
HHHHHHCCCCCCCCCHHHEEEHHCCCCCCEEECCCCCCCCCEEHHHHHHHHHHHCCCCCC
KLDASGEPSV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]