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The map label for this gene is aroE [H]

Identifier: 162148738

GI number: 162148738

Start: 3053272

End: 3054150

Strand: Reverse

Name: aroE [H]

Synonym: GDI_2966

Alternate gene names: 162148738

Gene position: 3054150-3053272 (Counterclockwise)

Preceding gene: 162148739

Following gene: 162148737

Centisome position: 77.43

GC content: 71.1

Gene sequence:

>879_bases
ATGACCGGCGTCCCCCCCATGCGACGGGCGATCGGCGGCGGGACGATGCTGGCCGGAGTGATCGGCTGGCCGGTATCGCA
TTCGCGCTCGCCGCTGCTGCATAATTTCTGGCTGGCCCGGTACGGGATCGACGGGGCCTATGTCCCGCTGCCGGTGCGGC
CGGGCCTGTTCGATGTCGCGGTGCGCGGCTTGCAGGCGGCGGGCTTTCGCGGCGCCAACGTGACCATCCCGCACAAGGAA
GCGGCGTTCGCCATCGCCGATCACCTGCATCGCTCGGCGGTGCGTTCCGGGTCGGTCAACACCCTGGTCTTCGCCGGGGA
CGGCCGGATCGAAGCCCATTCGACCGATGGCGACGGCTTCGTCGCCAATCTGGAAGCCCACGGCGTCGATGTCACGCGCG
GTCCCGCCCTGGTGCTGGGCGCCGGCGGTGCCGCGCGGGCGATCGTGGCCAGCCTGACGGACAGGGGGATTGCGGTTTCG
ATCGCCAACCGGACCCGCGCCCGGGCGGAAGATCTGGCCCACGCGCTGGCATCCCCCGAAACACGGATTGCCGTGACCGA
CTGGGACCGCTGGACGGACGGCCTGCCGGACCATGCCCTGCTGGTCAACACGACGTCGCTGGGCATGCATGGCGGACCGG
ACGACGTGTTCGCGCCCGACCTGGCGCGTGCGCCGGCCGGCATGGTGGTGGCCGACATCGTCTATGTTCCGCGCATGACC
CCGCTGCTGCGGGCCGCCGCCGCGCGGGGGCTGCCGGTGGTGGACGGAACGGGCATGCTGCTGCACCAGGCGCGACTGGG
CTTTCGCGAATGGTTCGGCGTCGATCCGGCGGTGGATGCCGATATCCAGGCGCTGCTCGACGCCGACCTGGCAGGGTGA

Upstream 100 bases:

>100_bases
TGGAAATCCGCCAGGACCTGGTGGCCGATGCGGAAGGACAGCGCGAGTGGGCCGGGCGCCTGGCGCGGCTGCTGCCGCGC
GCCTGGGCACGGTACTCGGC

Downstream 100 bases:

>100_bases
CATGCGGGTTCTGGGCCTGACGGGCGGAATCGGCATGGGAAAATCGACGGTCGCCCGGATGCTGCGCTCCGCCGGCTTCC
CCATCTTCGATGCGGATGCC

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTGVPPMRRAIGGGTMLAGVIGWPVSHSRSPLLHNFWLARYGIDGAYVPLPVRPGLFDVAVRGLQAAGFRGANVTIPHKE
AAFAIADHLHRSAVRSGSVNTLVFAGDGRIEAHSTDGDGFVANLEAHGVDVTRGPALVLGAGGAARAIVASLTDRGIAVS
IANRTRARAEDLAHALASPETRIAVTDWDRWTDGLPDHALLVNTTSLGMHGGPDDVFAPDLARAPAGMVVADIVYVPRMT
PLLRAAAARGLPVVDGTGMLLHQARLGFREWFGVDPAVDADIQALLDADLAG

Sequences:

>Translated_292_residues
MTGVPPMRRAIGGGTMLAGVIGWPVSHSRSPLLHNFWLARYGIDGAYVPLPVRPGLFDVAVRGLQAAGFRGANVTIPHKE
AAFAIADHLHRSAVRSGSVNTLVFAGDGRIEAHSTDGDGFVANLEAHGVDVTRGPALVLGAGGAARAIVASLTDRGIAVS
IANRTRARAEDLAHALASPETRIAVTDWDRWTDGLPDHALLVNTTSLGMHGGPDDVFAPDLARAPAGMVVADIVYVPRMT
PLLRAAAARGLPVVDGTGMLLHQARLGFREWFGVDPAVDADIQALLDADLAG
>Mature_291_residues
TGVPPMRRAIGGGTMLAGVIGWPVSHSRSPLLHNFWLARYGIDGAYVPLPVRPGLFDVAVRGLQAAGFRGANVTIPHKEA
AFAIADHLHRSAVRSGSVNTLVFAGDGRIEAHSTDGDGFVANLEAHGVDVTRGPALVLGAGGAARAIVASLTDRGIAVSI
ANRTRARAEDLAHALASPETRIAVTDWDRWTDGLPDHALLVNTTSLGMHGGPDDVFAPDLARAPAGMVVADIVYVPRMTP
LLRAAAARGLPVVDGTGMLLHQARLGFREWFGVDPAVDADIQALLDADLAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=273, Percent_Identity=36.2637362637363, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787983, Length=270, Percent_Identity=32.5925925925926, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320332, Length=272, Percent_Identity=30.5147058823529, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30476; Mature: 30345

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVPPMRRAIGGGTMLAGVIGWPVSHSRSPLLHNFWLARYGIDGAYVPLPVRPGLFDVA
CCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHH
VRGLQAAGFRGANVTIPHKEAAFAIADHLHRSAVRSGSVNTLVFAGDGRIEAHSTDGDGF
HHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCE
VANLEAHGVDVTRGPALVLGAGGAARAIVASLTDRGIAVSIANRTRARAEDLAHALASPE
EEEEEECCEEEECCCEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCC
TRIAVTDWDRWTDGLPDHALLVNTTSLGMHGGPDDVFAPDLARAPAGMVVADIVYVPRMT
CEEEEECCHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCH
PLLRAAAARGLPVVDGTGMLLHQARLGFREWFGVDPAVDADIQALLDADLAG
HHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TGVPPMRRAIGGGTMLAGVIGWPVSHSRSPLLHNFWLARYGIDGAYVPLPVRPGLFDVA
CCCCHHHHHHCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHH
VRGLQAAGFRGANVTIPHKEAAFAIADHLHRSAVRSGSVNTLVFAGDGRIEAHSTDGDGF
HHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCE
VANLEAHGVDVTRGPALVLGAGGAARAIVASLTDRGIAVSIANRTRARAEDLAHALASPE
EEEEEECCEEEECCCEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCC
TRIAVTDWDRWTDGLPDHALLVNTTSLGMHGGPDDVFAPDLARAPAGMVVADIVYVPRMT
CEEEEECCHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCH
PLLRAAAARGLPVVDGTGMLLHQARLGFREWFGVDPAVDADIQALLDADLAG
HHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA