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The map label for this gene is exsB

Identifier: 162148727

GI number: 162148727

Start: 3043404

End: 3044141

Strand: Direct

Name: exsB

Synonym: GDI_2955

Alternate gene names: 162148727

Gene position: 3043404-3044141 (Clockwise)

Preceding gene: 162148726

Following gene: 162148728

Centisome position: 77.16

GC content: 69.24

Gene sequence:

>738_bases
ATGGCCACATCCCTGACCCCCGCCGATCCGTTGCAGGAAGCCGCGATCGTGCTGTTTTCCGGCGGGCAGGATTCCGCGAC
CTGCCTGGCCTGGGCCCTGTCGCGCTTCGGCCGGGTGGAAACCGTGGGCTTCGATTACGGACAGCGCCATGCGGTGGAAC
TGGCCTGCCGGGCGCGGCTGCGCGACGGAATGGCGGCGCTGGACCCGGACTGGGCCACCCGGCTGGGCCAGGACCATACG
CTGGCGCTGGACGCTCTGGGGACGGTGTCGGACACCGCGCTGACGCGCGATGCCGCGATCACGATGAACGAGAACGGGCT
TCCCAGCACCTTCGTCCCCGGACGCAACCTGATCTTCCTGACCTTCGCGGCGGCGCTGGCCGCGCGGCGGGGCGCGCGCC
ACATCGTCGGCGGCATGTGCGAGACCGATTATTCCGGCTATCCCGACTGCCGCGACGACACGATCAAGGCGATGCAGGTC
GCGCTGAACCTAGGCATGGCCAGCCGCTACGTGCTGCACACGCCGCTGATGTGGATCGACAAGGCCGAGACCTGGCGCAT
GGCCGAGGGACTGGGCGGTGCCGACCTGGTCGAGCTGATCAACCGCGAGAGCCATAGCTGCTATCTGGGCGTGCGCGACG
TGATGCATCCCTGGGGCCATGGCTGCGGCACCTGCCCCGCCTGCATGCTGCGCCGCGCGGGATGGGAACGCTATGTCGCG
GACGGCGCCGATGCTTGA

Upstream 100 bases:

>100_bases
CCCAGGCCGCGAACACGGCGGCGGCCGTCGCCTATTGCCGCGCCCACCCGCGCTGGCGCTTGTCGCTGCAAACCCACAAG
CTGATCGGGATACCCTAGAA

Downstream 100 bases:

>100_bases
CCTGGTCTTCACGCGCCGCTTTTCGATGGGGCACCGGCTGATTCACGACGCCAGCGAGAGCTGCGCCCTGCCCCACGGCC
ACAACGAGTTCGTGACCGTG

Product: succinoglycan protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MATSLTPADPLQEAAIVLFSGGQDSATCLAWALSRFGRVETVGFDYGQRHAVELACRARLRDGMAALDPDWATRLGQDHT
LALDALGTVSDTALTRDAAITMNENGLPSTFVPGRNLIFLTFAAALAARRGARHIVGGMCETDYSGYPDCRDDTIKAMQV
ALNLGMASRYVLHTPLMWIDKAETWRMAEGLGGADLVELINRESHSCYLGVRDVMHPWGHGCGTCPACMLRRAGWERYVA
DGADA

Sequences:

>Translated_245_residues
MATSLTPADPLQEAAIVLFSGGQDSATCLAWALSRFGRVETVGFDYGQRHAVELACRARLRDGMAALDPDWATRLGQDHT
LALDALGTVSDTALTRDAAITMNENGLPSTFVPGRNLIFLTFAAALAARRGARHIVGGMCETDYSGYPDCRDDTIKAMQV
ALNLGMASRYVLHTPLMWIDKAETWRMAEGLGGADLVELINRESHSCYLGVRDVMHPWGHGCGTCPACMLRRAGWERYVA
DGADA
>Mature_244_residues
ATSLTPADPLQEAAIVLFSGGQDSATCLAWALSRFGRVETVGFDYGQRHAVELACRARLRDGMAALDPDWATRLGQDHTL
ALDALGTVSDTALTRDAAITMNENGLPSTFVPGRNLIFLTFAAALAARRGARHIVGGMCETDYSGYPDCRDDTIKAMQVA
LNLGMASRYVLHTPLMWIDKAETWRMAEGLGGADLVELINRESHSCYLGVRDVMHPWGHGCGTCPACMLRRAGWERYVAD
GADA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=233, Percent_Identity=45.0643776824034, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_GLUDA (A9HRF6)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001603188.1
- RefSeq:   YP_002277735.1
- ProteinModelPortal:   A9HRF6
- SMR:   A9HRF6
- GeneID:   5791777
- GeneID:   6976840
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_3394
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK864419
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26507; Mature: 26376

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSLTPADPLQEAAIVLFSGGQDSATCLAWALSRFGRVETVGFDYGQRHAVELACRARL
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
RDGMAALDPDWATRLGQDHTLALDALGTVSDTALTRDAAITMNENGLPSTFVPGRNLIFL
HCCCCCCCCHHHHHCCCCCEEEEHHHCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHH
TFAAALAARRGARHIVGGMCETDYSGYPDCRDDTIKAMQVALNLGMASRYVLHTPLMWID
HHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCHHEEC
KAETWRMAEGLGGADLVELINRESHSCYLGVRDVMHPWGHGCGTCPACMLRRAGWERYVA
CCHHHHHHHCCCCHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCHHHHHHHCCCHHHHC
DGADA
CCCCC
>Mature Secondary Structure 
ATSLTPADPLQEAAIVLFSGGQDSATCLAWALSRFGRVETVGFDYGQRHAVELACRARL
CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHH
RDGMAALDPDWATRLGQDHTLALDALGTVSDTALTRDAAITMNENGLPSTFVPGRNLIFL
HCCCCCCCCHHHHHCCCCCEEEEHHHCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHH
TFAAALAARRGARHIVGGMCETDYSGYPDCRDDTIKAMQVALNLGMASRYVLHTPLMWID
HHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCHHEEC
KAETWRMAEGLGGADLVELINRESHSCYLGVRDVMHPWGHGCGTCPACMLRRAGWERYVA
CCHHHHHHHCCCCHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCHHHHHHHCCCHHHHC
DGADA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA