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The map label for this gene is gst [H]

Identifier: 162148550

GI number: 162148550

Start: 2860556

End: 2861191

Strand: Reverse

Name: gst [H]

Synonym: GDI_2774

Alternate gene names: 162148550

Gene position: 2861191-2860556 (Counterclockwise)

Preceding gene: 162148551

Following gene: 162148549

Centisome position: 72.54

GC content: 64.94

Gene sequence:

>636_bases
ATGCTTGATGTCTATGCTTTCGCGACGCCCAACAGCGTCAAGGTGCCGATCGCGCTGGAGGAACTGGGGCTTCCCTATAC
GCTGCACGGCGTCAATGTCCGCAAGGGCGAACAGAAGACGCCGGAGTTCCTCAGGCTGAACCCCAACGGCAAGGTGCCGG
TCCTCGTCGACACGCCCGAGAGCGGCGATCCGTTCGTCCTCACGGAATCAGCGGCGATCCTCGTTTATCTCGCCGAGAAA
ACCGGGCGGCTTCTGCCGGCCAGCGGGGAAGAGCGCGCCCGCGTTTTCGAGCAGCTTTTCTTTCACGCGTCCGGTCTGAG
TCCTGCTTTCGGCCAGTCCGGCTTCTTCCAGCGCTTCGCCGCCGAGCCTCAGCCCCTTGCCATCGAGCGTTTCGCCGCCG
AAGCGACACGCACCCTGGGCGTGCTCGACGGCGTGCTGGCGGACCGCCCCTTCGTTGCCGGGGCAGACTTCACCATCGCG
GACATCGCCCATTTCGGCTGGCTGTGGCGTCGTGGTTTTCCCAACATCACATTCAGTGACGCAACGCATGTCGCCCGCTG
GTACGAGACGGTCGAAGCACGCCCGGCCGTGCAACGCGGCATCGCCCGCGTCGAAGCGCTCGTCCCGCAAGACTGA

Upstream 100 bases:

>100_bases
GCCTTCCAGCTCACCGGCAGCCCGCTGCTTCATGCCCTGTTGGCGTTGGTCGGGCATGTCCTCTCCGGCCCGCAAGCCCG
CCAAGAAGGAGAAAACGACG

Downstream 100 bases:

>100_bases
CGTCATCCCTTTCAAGGAAAACATCATGTCCATGCTTTTCACGCCTTTCAGGGCAGGCGCGCTGTCGCTCGGTCATCGGG
TCGTCATGGCGCCGCTCACC

Product: glutathionine S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLDVYAFATPNSVKVPIALEELGLPYTLHGVNVRKGEQKTPEFLRLNPNGKVPVLVDTPESGDPFVLTESAAILVYLAEK
TGRLLPASGEERARVFEQLFFHASGLSPAFGQSGFFQRFAAEPQPLAIERFAAEATRTLGVLDGVLADRPFVAGADFTIA
DIAHFGWLWRRGFPNITFSDATHVARWYETVEARPAVQRGIARVEALVPQD

Sequences:

>Translated_211_residues
MLDVYAFATPNSVKVPIALEELGLPYTLHGVNVRKGEQKTPEFLRLNPNGKVPVLVDTPESGDPFVLTESAAILVYLAEK
TGRLLPASGEERARVFEQLFFHASGLSPAFGQSGFFQRFAAEPQPLAIERFAAEATRTLGVLDGVLADRPFVAGADFTIA
DIAHFGWLWRRGFPNITFSDATHVARWYETVEARPAVQRGIARVEALVPQD
>Mature_211_residues
MLDVYAFATPNSVKVPIALEELGLPYTLHGVNVRKGEQKTPEFLRLNPNGKVPVLVDTPESGDPFVLTESAAILVYLAEK
TGRLLPASGEERARVFEQLFFHASGLSPAFGQSGFFQRFAAEPQPLAIERFAAEATRTLGVLDGVLADRPFVAGADFTIA
DIAHFGWLWRRGFPNITFSDATHVARWYETVEARPAVQRGIARVEALVPQD

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=217, Percent_Identity=34.5622119815668, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI124249394, Length=217, Percent_Identity=34.5622119815668, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=39.7129186602871, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI87082195, Length=218, Percent_Identity=38.9908256880734, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87081789, Length=168, Percent_Identity=29.7619047619048, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=148, Percent_Identity=36.4864864864865, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI17864598, Length=197, Percent_Identity=32.994923857868, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571670, Length=174, Percent_Identity=31.0344827586207, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17864592, Length=181, Percent_Identity=32.5966850828729, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646249, Length=165, Percent_Identity=32.1212121212121, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI85725204, Length=197, Percent_Identity=30.4568527918782, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737923, Length=197, Percent_Identity=30.4568527918782, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17933730, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19922932, Length=169, Percent_Identity=33.1360946745562, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17864594, Length=187, Percent_Identity=30.4812834224599, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646251, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17864596, Length=211, Percent_Identity=25.1184834123223, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21686985, Length=205, Percent_Identity=30.2439024390244, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45549270, Length=177, Percent_Identity=29.3785310734463, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922160, Length=194, Percent_Identity=31.4432989690722, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23165; Mature: 23165

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDVYAFATPNSVKVPIALEELGLPYTLHGVNVRKGEQKTPEFLRLNPNGKVPVLVDTPE
CCEEEEEECCCCEEEEEEHHHCCCCEEEECCEECCCCCCCCCEEEECCCCCEEEEEECCC
SGDPFVLTESAAILVYLAEKTGRLLPASGEERARVFEQLFFHASGLSPAFGQSGFFQRFA
CCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHC
AEPQPLAIERFAAEATRTLGVLDGVLADRPFVAGADFTIADIAHFGWLWRRGFPNITFSD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHCCCCCCEECC
ATHVARWYETVEARPAVQRGIARVEALVPQD
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDVYAFATPNSVKVPIALEELGLPYTLHGVNVRKGEQKTPEFLRLNPNGKVPVLVDTPE
CCEEEEEECCCCEEEEEEHHHCCCCEEEECCEECCCCCCCCCEEEECCCCCEEEEEECCC
SGDPFVLTESAAILVYLAEKTGRLLPASGEERARVFEQLFFHASGLSPAFGQSGFFQRFA
CCCCEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHC
AEPQPLAIERFAAEATRTLGVLDGVLADRPFVAGADFTIADIAHFGWLWRRGFPNITFSD
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHCCCCCCEECC
ATHVARWYETVEARPAVQRGIARVEALVPQD
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]