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The map label for this gene is udp [H]

Identifier: 162148476

GI number: 162148476

Start: 2791020

End: 2791802

Strand: Direct

Name: udp [H]

Synonym: GDI_2696

Alternate gene names: 162148476

Gene position: 2791020-2791802 (Clockwise)

Preceding gene: 162148475

Following gene: 162148477

Centisome position: 70.76

GC content: 62.84

Gene sequence:

>783_bases
ATGTCAGAACGCGAAGATATAAAAACGGCCTGGTATATCGGCGCGACGTCCGCGGACGTCGGCAAGGTGGCGATCCTGGT
CGGAGATCCGGCCCGCGTCGATAGAATCGCCCTTCTACTGGACGATGTGCATCGCGTGCCGATCAGCAGGGGATTGCAGA
CCATCACCGGCACCCACGCCGGCCGGCGGGTCACGGTAACCGCCTTCGGAATGGGGGCGCCGATCGCCGTGGTGGTCATG
GAGGAACTGCGCGCTCTGGGGGTCGGGCTTTTTCTGCGCATCGGCACCGCGATGGCGGCCGGACCGGTTTCCCTGGGTGA
TTTCGTGGTTGCGGAAGGTGCCCTGCGCCGCGAAGGAACTTCGGCCAGCTATGCCCCGGCGGGGTATCCGGCATTGGCCG
ACCGTTCCCTGAACGAGGTGATTCTCGATCGCCTGAAATCCGGAAAACACCCCTATTATTCAGGGGTCTTCGCAAGCTAT
GACGGTTTCTACTCGGAGATGTTCACCCTGCCCGGCGCGCGCCAGCGGGTCCGTCCGGAACTGCTGGCCGATATCGGGAA
CTACGGCCTGATCGCAGCCGACATGGAGACGTCCGCCCTTCTGGTCGCGGGACGCATGCTGGATGCGCGTGTTTCGAGCC
TGTGCATGGCCACTGTTGACCCCGTAACCCAAGCCAAGCTGGACGCAGCCGCCACGACCGCCACCGAACACGAACTGTTC
CAGATCGCGCTCGACAGTGTTTCGAACGCCTCCTTTCACGAGGAAGAGGAGACAGACTCATGA

Upstream 100 bases:

>100_bases
TACGCGACAACGCCGATCCGGATACTGCGCTGGGCGCCGGCATGGAGGCCGCGCGAGCCATGCTGTCCGAACGGCAAAAC
GACAAGAGAGCCTAAGGAAC

Downstream 100 bases:

>100_bases
CCGATATCATCAACGAATATTTCGATGTTCTTGCCTCGCGTCTCGAATTCGTCAAGACGACGCAGCACGATGCCATTCGG
CGCGCGGCGCGGCTCTGTGC

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSEREDIKTAWYIGATSADVGKVAILVGDPARVDRIALLLDDVHRVPISRGLQTITGTHAGRRVTVTAFGMGAPIAVVVM
EELRALGVGLFLRIGTAMAAGPVSLGDFVVAEGALRREGTSASYAPAGYPALADRSLNEVILDRLKSGKHPYYSGVFASY
DGFYSEMFTLPGARQRVRPELLADIGNYGLIAADMETSALLVAGRMLDARVSSLCMATVDPVTQAKLDAAATTATEHELF
QIALDSVSNASFHEEEETDS

Sequences:

>Translated_260_residues
MSEREDIKTAWYIGATSADVGKVAILVGDPARVDRIALLLDDVHRVPISRGLQTITGTHAGRRVTVTAFGMGAPIAVVVM
EELRALGVGLFLRIGTAMAAGPVSLGDFVVAEGALRREGTSASYAPAGYPALADRSLNEVILDRLKSGKHPYYSGVFASY
DGFYSEMFTLPGARQRVRPELLADIGNYGLIAADMETSALLVAGRMLDARVSSLCMATVDPVTQAKLDAAATTATEHELF
QIALDSVSNASFHEEEETDS
>Mature_259_residues
SEREDIKTAWYIGATSADVGKVAILVGDPARVDRIALLLDDVHRVPISRGLQTITGTHAGRRVTVTAFGMGAPIAVVVME
ELRALGVGLFLRIGTAMAAGPVSLGDFVVAEGALRREGTSASYAPAGYPALADRSLNEVILDRLKSGKHPYYSGVFASYD
GFYSEMFTLPGARQRVRPELLADIGNYGLIAADMETSALLVAGRMLDARVSSLCMATVDPVTQAKLDAAATTATEHELFQ
IALDSVSNASFHEEEETDS

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=242, Percent_Identity=29.7520661157025, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790844, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27635; Mature: 27504

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEREDIKTAWYIGATSADVGKVAILVGDPARVDRIALLLDDVHRVPISRGLQTITGTHA
CCCCHHCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCHHHHCHHHHHCCCC
GRRVTVTAFGMGAPIAVVVMEELRALGVGLFLRIGTAMAAGPVSLGDFVVAEGALRREGT
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHCCCC
SASYAPAGYPALADRSLNEVILDRLKSGKHPYYSGVFASYDGFYSEMFTLPGARQRVRPE
CCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCHH
LLADIGNYGLIAADMETSALLVAGRMLDARVSSLCMATVDPVTQAKLDAAATTATEHELF
HHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QIALDSVSNASFHEEEETDS
HHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEREDIKTAWYIGATSADVGKVAILVGDPARVDRIALLLDDVHRVPISRGLQTITGTHA
CCCHHCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCHHHHCHHHHHCCCC
GRRVTVTAFGMGAPIAVVVMEELRALGVGLFLRIGTAMAAGPVSLGDFVVAEGALRREGT
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHCCCC
SASYAPAGYPALADRSLNEVILDRLKSGKHPYYSGVFASYDGFYSEMFTLPGARQRVRPE
CCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCHH
LLADIGNYGLIAADMETSALLVAGRMLDARVSSLCMATVDPVTQAKLDAAATTATEHELF
HHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QIALDSVSNASFHEEEETDS
HHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]