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The map label for this gene is exuR [H]

Identifier: 162148449

GI number: 162148449

Start: 2760697

End: 2761524

Strand: Direct

Name: exuR [H]

Synonym: GDI_2668

Alternate gene names: 162148449

Gene position: 2760697-2761524 (Clockwise)

Preceding gene: 162148442

Following gene: 162148451

Centisome position: 69.99

GC content: 67.87

Gene sequence:

>828_bases
TTGGTCCGGCCAATGTCAAGATTGGTCAGACCAATTTGCGACCCGCGCGATCACGCTTCAGCGAGGCCGGCGCGAGACGA
GGACAGACGATACATGGCCGAAAGCGGCGCCAATCGCCGGCTCTACCAGCCGATTGCCCAGGCGATCCTGAAACTGATCG
AGGCGGGCGACGTCCCGCCCGGACGGATGCTGCCGCCCGAGCGCGAACTGTCCGTCCGGTTCGGCGTCAGTCGCTCCACC
GTGCGCGAGGCGATCATCGCGCTGGAGGTGATGGGCATTGTCGAGGTCCGGGTCGGCGCGGGCGTGATGGTGCTGGCGCC
GGCGACGGCGCGTTCCAGCCTGGCGCGGACACGACTGCTGGAGCCCGATCCGGAACTGCCGGTGCCGATCGACCTGGAAA
CCGAGGTCCCGCCCTTCGACCTGCTGCAGGCGCGGCTGCTGATCGAACCGGAAACGGCGGCGCTGGCAGCGCAGAACGCG
GGCCCGCGCGAGCGCGCGATGATCGAAGCGGCGTTCCGGCAGAATATCGCGGACAACGCCCGTGGGTCACGAACCCATCC
GGGCGACCGCCTGTTTCACATCCGCATCGCGCAGGCCAGCGGCAACAGCGCCTATGAACTGACGATCATGCTGCTGCTGG
GCCATCGCTATGGCGACCTGTTCCGCCGTCTCCAGCAGCTTTATACCCCCCAGGACATGCCCGGCCGTTCCGAACACGAA
CATGCGGCGATACTGGAGGCGATCCTGGCGGCCGACCCGCCGCGCGCGCGCGAGGCGATGCGCCGGCACATCCAGGCGGT
GATCGGGATATTCTCGCGCGACACCTGA

Upstream 100 bases:

>100_bases
GCGACCGATGCCGTTGGCTGCCGCCGTGATCAGAGCCCGTTTGCCCGCCAGTCGCATGACGATCCCGCCTTGTTATTGCT
TTGGTGAATCTCCTATTAAA

Downstream 100 bases:

>100_bases
CTGCCGATCCTGTAGGGCGTCAGGCGACCGATCGGCCATTCGCCACCAGCATCATATCGACAACGGAAGCCCGGCCTCGG
CCTTCACCTCCTCCATGACC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MVRPMSRLVRPICDPRDHASARPARDEDRRYMAESGANRRLYQPIAQAILKLIEAGDVPPGRMLPPERELSVRFGVSRST
VREAIIALEVMGIVEVRVGAGVMVLAPATARSSLARTRLLEPDPELPVPIDLETEVPPFDLLQARLLIEPETAALAAQNA
GPRERAMIEAAFRQNIADNARGSRTHPGDRLFHIRIAQASGNSAYELTIMLLLGHRYGDLFRRLQQLYTPQDMPGRSEHE
HAAILEAILAADPPRAREAMRRHIQAVIGIFSRDT

Sequences:

>Translated_275_residues
MVRPMSRLVRPICDPRDHASARPARDEDRRYMAESGANRRLYQPIAQAILKLIEAGDVPPGRMLPPERELSVRFGVSRST
VREAIIALEVMGIVEVRVGAGVMVLAPATARSSLARTRLLEPDPELPVPIDLETEVPPFDLLQARLLIEPETAALAAQNA
GPRERAMIEAAFRQNIADNARGSRTHPGDRLFHIRIAQASGNSAYELTIMLLLGHRYGDLFRRLQQLYTPQDMPGRSEHE
HAAILEAILAADPPRAREAMRRHIQAVIGIFSRDT
>Mature_275_residues
MVRPMSRLVRPICDPRDHASARPARDEDRRYMAESGANRRLYQPIAQAILKLIEAGDVPPGRMLPPERELSVRFGVSRST
VREAIIALEVMGIVEVRVGAGVMVLAPATARSSLARTRLLEPDPELPVPIDLETEVPPFDLLQARLLIEPETAALAAQNA
GPRERAMIEAAFRQNIADNARGSRTHPGDRLFHIRIAQASGNSAYELTIMLLLGHRYGDLFRRLQQLYTPQDMPGRSEHE
HAAILEAILAADPPRAREAMRRHIQAVIGIFSRDT

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=232, Percent_Identity=32.7586206896552, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790780, Length=246, Percent_Identity=32.520325203252, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790032, Length=239, Percent_Identity=28.0334728033473, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786303, Length=230, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 30585; Mature: 30585

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRPMSRLVRPICDPRDHASARPARDEDRRYMAESGANRRLYQPIAQAILKLIEAGDVPP
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
GRMLPPERELSVRFGVSRSTVREAIIALEVMGIVEVRVGAGVMVLAPATARSSLARTRLL
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCC
EPDPELPVPIDLETEVPPFDLLQARLLIEPETAALAAQNAGPRERAMIEAAFRQNIADNA
CCCCCCCCCCCCCCCCCCHHHHHHHHEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
RGSRTHPGDRLFHIRIAQASGNSAYELTIMLLLGHRYGDLFRRLQQLYTPQDMPGRSEHE
CCCCCCCCCEEEEEEEEECCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
HAAILEAILAADPPRAREAMRRHIQAVIGIFSRDT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRPMSRLVRPICDPRDHASARPARDEDRRYMAESGANRRLYQPIAQAILKLIEAGDVPP
CCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
GRMLPPERELSVRFGVSRSTVREAIIALEVMGIVEVRVGAGVMVLAPATARSSLARTRLL
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCC
EPDPELPVPIDLETEVPPFDLLQARLLIEPETAALAAQNAGPRERAMIEAAFRQNIADNA
CCCCCCCCCCCCCCCCCCHHHHHHHHEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
RGSRTHPGDRLFHIRIAQASGNSAYELTIMLLLGHRYGDLFRRLQQLYTPQDMPGRSEHE
CCCCCCCCCEEEEEEEEECCCCCHHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
HAAILEAILAADPPRAREAMRRHIQAVIGIFSRDT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA