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The map label for this gene is mbaA [H]

Identifier: 162148372

GI number: 162148372

Start: 2682634

End: 2684202

Strand: Reverse

Name: mbaA [H]

Synonym: GDI_2590

Alternate gene names: 162148372

Gene position: 2684202-2682634 (Counterclockwise)

Preceding gene: 162148373

Following gene: 162148369

Centisome position: 68.06

GC content: 65.01

Gene sequence:

>1569_bases
ATGACGCTCAATAGACGCGCATTCGCGGTCCTGCTGCCGATCGTCCTGCTGGGCCACATCCTGGCCGGCGGGGCGGCGTT
CCTGGGATACCGTACCGCACTGGTCCTGCTGCACAAGGCGCGCGTGCAGCAGGAACTGTTCCAGCTCAAGACGTCCTATT
CCGATTATGTGTCGCTCGAAGCGCAGTTGCTGTACGTCATCCGCAACAGCAGCGCCTTCATGTCCTTCATCAACGAATCC
GATCAGGCCTACCGGACCCGTGTCCTGGCCATCGGAATCCAGGACAGCCTGCAATCACTCGTTCCCAATGACGGGACGAA
GGTGTCGTGCAGCGTCTTCCAGTCCGATGGGCGCGAGATCTTCTATTTCGACAACGGCCTGGACCCGTTCCAGACGCTGG
GCGAGCATCAGGCGGCATTCGCGCACGCCGTCCTGACCGACAACGCGCTGTCGCGCACCGGCCTGGTGACGGAAAAGGAC
GGCACGACCTATCTGCTGGATGCGGCGGAAGTTCAGGCGCGGGGCAATCGCCCGGTTTCCTCCGGGATGCTGCCGGAACA
GTCCGTCCTGTTGCAGATCGCTGTGAAGCCCAGCCGTTTCGAGACGATTCGCCACACCCTGGCGGTCGAGTACGGGGCAC
CGGTCGAATTGTCGGCCACACCGCCGGTGCCGGGCAGGGGGCTGTCCGCCAGCGTCCGACTGGCACCCGCGCTGTACGCC
CGGGTAACCCCGGCCGGGTCCTATATGCGGGCGAAGCTGACGCGGGTCGCGATGGTGATCGGGATGTTCGTCGTGGTCCT
CAGCGTGATGTCGGTCGGTGTGCTGATGCTGCTGGTGCGGCGCTATATCATCGCACCGATCGAGGAACTGGACCGGCAGG
TGACGGCGATCATGGAAAAGCGCCGGATCGACATCGATGTGCCCGAACGGGGTGAGATCGGGCGGCTGGCGGCGAATGTG
CGGATGCTGCACGGGCAACTGGCGCGGGCGCTGCGCAAGACCCGGCGGCTGTACGAGACGGATTCGGTGACGGGCATCGG
CAACCGGATCTATTTCAACGAAATGCTGGAACGGTTCTTTCTGGACAGCGCCGAAACCGGCCGCCCGCTGACCATGCTGT
TCATCGACCTGGACAATTTCAAACAGGTCAATGACGAGCACGGCCATCGGACCGGTGATGCCCTGCTGGTGGCGGTGGCC
AAGGCGCTGGTGGCCTCGGCCGCCGAGACGGCGGAGGCCTGCAACGAACCGCCGGGCATCGCTGCGCGCCTGTCGGGGGA
TGAATTCGCCTTCCTGATCCAGGCCGAGCCGCGCAGCGCCGCGGTGCAGATGCTGATTCAGTCGTTCCTGGTAAAGTTCC
GCTGCGGGTTTGCTGTCGAGTCCGACTCATACCCGGTGACCGCCAGCGTCGGTGTGGCCGCCGTGCCGGGCGACGCCGAT
ACGCCCACGCACCTGATGTCGTGCGCGGACCATGCGATGTACTACGCCAAGGCGGCGGGGCGGAACACGTTCGCGTTCTA
CAGCGACCTGCCGCCCTCGGCCCGTACGCCGGGTGTACGCGTCCCCTAG

Upstream 100 bases:

>100_bases
ATCTATCCGCCCCAATCCTACCCCATCATCTATCGCAAGCCCGTGCCGACCGACAGCCTGGCGTTGCGGAGGCGGATTCT
CGGCGCCCTGATTGCGATCC

Downstream 100 bases:

>100_bases
CGCTCAGGCGGTCGGTGCGGGAACAAGCAGCGCCGCCACCTGTTCCAGGACCAGCCGATCCTGCGGTGTGAAACGGTCCC
TGATCGGGCTGTCGATATCC

Product: GGDEF family signaling protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 521

Protein sequence:

>522_residues
MTLNRRAFAVLLPIVLLGHILAGGAAFLGYRTALVLLHKARVQQELFQLKTSYSDYVSLEAQLLYVIRNSSAFMSFINES
DQAYRTRVLAIGIQDSLQSLVPNDGTKVSCSVFQSDGREIFYFDNGLDPFQTLGEHQAAFAHAVLTDNALSRTGLVTEKD
GTTYLLDAAEVQARGNRPVSSGMLPEQSVLLQIAVKPSRFETIRHTLAVEYGAPVELSATPPVPGRGLSASVRLAPALYA
RVTPAGSYMRAKLTRVAMVIGMFVVVLSVMSVGVLMLLVRRYIIAPIEELDRQVTAIMEKRRIDIDVPERGEIGRLAANV
RMLHGQLARALRKTRRLYETDSVTGIGNRIYFNEMLERFFLDSAETGRPLTMLFIDLDNFKQVNDEHGHRTGDALLVAVA
KALVASAAETAEACNEPPGIAARLSGDEFAFLIQAEPRSAAVQMLIQSFLVKFRCGFAVESDSYPVTASVGVAAVPGDAD
TPTHLMSCADHAMYYAKAAGRNTFAFYSDLPPSARTPGVRVP

Sequences:

>Translated_522_residues
MTLNRRAFAVLLPIVLLGHILAGGAAFLGYRTALVLLHKARVQQELFQLKTSYSDYVSLEAQLLYVIRNSSAFMSFINES
DQAYRTRVLAIGIQDSLQSLVPNDGTKVSCSVFQSDGREIFYFDNGLDPFQTLGEHQAAFAHAVLTDNALSRTGLVTEKD
GTTYLLDAAEVQARGNRPVSSGMLPEQSVLLQIAVKPSRFETIRHTLAVEYGAPVELSATPPVPGRGLSASVRLAPALYA
RVTPAGSYMRAKLTRVAMVIGMFVVVLSVMSVGVLMLLVRRYIIAPIEELDRQVTAIMEKRRIDIDVPERGEIGRLAANV
RMLHGQLARALRKTRRLYETDSVTGIGNRIYFNEMLERFFLDSAETGRPLTMLFIDLDNFKQVNDEHGHRTGDALLVAVA
KALVASAAETAEACNEPPGIAARLSGDEFAFLIQAEPRSAAVQMLIQSFLVKFRCGFAVESDSYPVTASVGVAAVPGDAD
TPTHLMSCADHAMYYAKAAGRNTFAFYSDLPPSARTPGVRVP
>Mature_521_residues
TLNRRAFAVLLPIVLLGHILAGGAAFLGYRTALVLLHKARVQQELFQLKTSYSDYVSLEAQLLYVIRNSSAFMSFINESD
QAYRTRVLAIGIQDSLQSLVPNDGTKVSCSVFQSDGREIFYFDNGLDPFQTLGEHQAAFAHAVLTDNALSRTGLVTEKDG
TTYLLDAAEVQARGNRPVSSGMLPEQSVLLQIAVKPSRFETIRHTLAVEYGAPVELSATPPVPGRGLSASVRLAPALYAR
VTPAGSYMRAKLTRVAMVIGMFVVVLSVMSVGVLMLLVRRYIIAPIEELDRQVTAIMEKRRIDIDVPERGEIGRLAANVR
MLHGQLARALRKTRRLYETDSVTGIGNRIYFNEMLERFFLDSAETGRPLTMLFIDLDNFKQVNDEHGHRTGDALLVAVAK
ALVASAAETAEACNEPPGIAARLSGDEFAFLIQAEPRSAAVQMLIQSFLVKFRCGFAVESDSYPVTASVGVAAVPGDADT
PTHLMSCADHAMYYAKAAGRNTFAFYSDLPPSARTPGVRVP

Specific function: Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type I membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=180, Percent_Identity=31.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=179, Percent_Identity=29.608938547486, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=170, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788956, Length=269, Percent_Identity=26.3940520446097, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787262, Length=176, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788381, Length=179, Percent_Identity=30.1675977653631, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081881, Length=164, Percent_Identity=31.7073170731707, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788085, Length=195, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00672 HAMP [H]

EC number: NA

Molecular weight: Translated: 56979; Mature: 56848

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNRRAFAVLLPIVLLGHILAGGAAFLGYRTALVLLHKARVQQELFQLKTSYSDYVSLE
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
AQLLYVIRNSSAFMSFINESDQAYRTRVLAIGIQDSLQSLVPNDGTKVSCSVFQSDGREI
EEEEEEEECCHHHHHHHCCCCHHHHEEEEEEEHHHHHHHHCCCCCCEEEEEEEECCCCEE
FYFDNGLDPFQTLGEHQAAFAHAVLTDNALSRTGLVTEKDGTTYLLDAAEVQARGNRPVS
EEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECCCCEEEEECHHHHCCCCCCCC
SGMLPEQSVLLQIAVKPSRFETIRHTLAVEYGAPVELSATPPVPGRGLSASVRLAPALYA
CCCCCCCCEEEEEEECCHHHHHHHHHHEEECCCCEEECCCCCCCCCCCCCCEEEHHHHHH
RVTPAGSYMRAKLTRVAMVIGMFVVVLSVMSVGVLMLLVRRYIIAPIEELDRQVTAIMEK
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RRIDIDVPERGEIGRLAANVRMLHGQLARALRKTRRLYETDSVTGIGNRIYFNEMLERFF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LDSAETGRPLTMLFIDLDNFKQVNDEHGHRTGDALLVAVAKALVASAAETAEACNEPPGI
CCCCCCCCCEEEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
AARLSGDEFAFLIQAEPRSAAVQMLIQSFLVKFRCGFAVESDSYPVTASVGVAAVPGDAD
EEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCCEEECCCCCC
TPTHLMSCADHAMYYAKAAGRNTFAFYSDLPPSARTPGVRVP
CHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLNRRAFAVLLPIVLLGHILAGGAAFLGYRTALVLLHKARVQQELFQLKTSYSDYVSLE
CCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
AQLLYVIRNSSAFMSFINESDQAYRTRVLAIGIQDSLQSLVPNDGTKVSCSVFQSDGREI
EEEEEEEECCHHHHHHHCCCCHHHHEEEEEEEHHHHHHHHCCCCCCEEEEEEEECCCCEE
FYFDNGLDPFQTLGEHQAAFAHAVLTDNALSRTGLVTEKDGTTYLLDAAEVQARGNRPVS
EEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECCCCEEEEECHHHHCCCCCCCC
SGMLPEQSVLLQIAVKPSRFETIRHTLAVEYGAPVELSATPPVPGRGLSASVRLAPALYA
CCCCCCCCEEEEEEECCHHHHHHHHHHEEECCCCEEECCCCCCCCCCCCCCEEEHHHHHH
RVTPAGSYMRAKLTRVAMVIGMFVVVLSVMSVGVLMLLVRRYIIAPIEELDRQVTAIMEK
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RRIDIDVPERGEIGRLAANVRMLHGQLARALRKTRRLYETDSVTGIGNRIYFNEMLERFF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LDSAETGRPLTMLFIDLDNFKQVNDEHGHRTGDALLVAVAKALVASAAETAEACNEPPGI
CCCCCCCCCEEEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
AARLSGDEFAFLIQAEPRSAAVQMLIQSFLVKFRCGFAVESDSYPVTASVGVAAVPGDAD
EEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCEEECCCCCCEEECCCEEECCCCCC
TPTHLMSCADHAMYYAKAAGRNTFAFYSDLPPSARTPGVRVP
CHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]