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The map label for this gene is kfoC [H]

Identifier: 162148319

GI number: 162148319

Start: 2633074

End: 2634228

Strand: Reverse

Name: kfoC [H]

Synonym: GDI_2536

Alternate gene names: 162148319

Gene position: 2634228-2633074 (Counterclockwise)

Preceding gene: 162148320

Following gene: 162148318

Centisome position: 66.79

GC content: 69.26

Gene sequence:

>1155_bases
ATGGCAGATCCCGTGATCGACATCCTGGTCCCGGCCTATAATGCCGAGCCGACCATCCGCGAGGCGATCGACAGCCTGCG
CAACCAGACGGTGCGCAATATCCGCATCGTCGTCGTCGATGACGGGTCGACGGATGCGACCGGCCGCATCCTGGCCGAAA
TGGCGGCACAGGACGGGCGGATCGTCGTGCTGACCCAGCCCAACGGGGGAATCGTCGCCGCCCTGACATACGGGCTTTCG
GTGTGCCGCGCCCCGTTCATCGCCCGGCACGATGCCGACGACCTGGCGGCCCCCGATCGCCTTGAACGCCAGATCCGCCA
TATGGAAGAGCACCCCGACTGCGTCGCGGTGTCCGGCAGTGGCAGCCATATCGACGCGCAGGGGCGGCCGACGGGCGGCC
GGGTACGGCTGGCGCGGATCGACAAGGCCGACCCGTTCTGGATTCCGGCGCGCGAGCCCTACCTGCCGCAGCCCTTCCTG
CTGATGCGGCGGGCCGCCTTCGACCTGGCCGGCGGATATCGCAGCCTGGCGGTGGCGGAAGACAGCGACCTGTACTGGCG
GCTGGACGATATCGGGACGCTGTCGAACATCGACCGGAATTTCGGGTCCTATCGCGTCCATGCGGGCAGCGTGTCCAGTG
CCTCGATCCGCAATGGCCGGTCCATGGCCTTCTGGTCGCAGATGGCCGCGCTGTCGGCGCGCCGCCGTCGCGCGGGCCAG
CCGGACCAGGTGTTCAGCCCTGCCGAGCTGCGACGATGCGAAGCGGCGGAAACGCTGGAGGAATTCTTTCGCGCCGGCTG
CCCCGGCCTGACCCAGGCCGAACGGTCCTGGCTGGCCCTGGCCCTGGGAATGAAGCTGGTCGCGCTGGCGTTCTACCGGC
CCTACGAACTGGATAGCGCGGATTGCGCGTTCATCGGCCGCGCGCTGCGCGACCGGGACGTGGCAATCGGCCGTGAAAAC
CGCGTCGAGATTGCCGAGCACCTGATGGCGACGGCAACCCGCCTGGCCGCGCATGGCCGTTTCGGCGATGCGCTGAAGCT
GGTGTCGCCCGCGCGCTATCCCGTGCTGCTGGGCCGGATTTCGTTCCGGCTGGTGCTGCCGTCGGGCCTGCGCGACGTCT
TCAAGCGCCTGGCGGGCCGCGCGCAACCGGCGTGA

Upstream 100 bases:

>100_bases
CGAATACATGTATACGCTGGAACCGACCAAGACCGGACAGGACCGGCCGCAGATGCTCGTCCTGGACCGTTACCTGACCC
ACCGGGGGAGATAAGGTGCA

Downstream 100 bases:

>100_bases
CGACACCGGAAAGACGACGAGACCCAGAGGAGGACCGCATGGCGGCAGAAGGACAGGGCGCGCGCGCGGGCGGGCTGGGC
AGGGCGGCCACCAGCGGGGT

Product: glycosyl transferase

Products: NA

Alternate protein names: CS; Chondroitin polymerase; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase; UDP-GalNAc transferase; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase; UDP-GlcUA transferase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MADPVIDILVPAYNAEPTIREAIDSLRNQTVRNIRIVVVDDGSTDATGRILAEMAAQDGRIVVLTQPNGGIVAALTYGLS
VCRAPFIARHDADDLAAPDRLERQIRHMEEHPDCVAVSGSGSHIDAQGRPTGGRVRLARIDKADPFWIPAREPYLPQPFL
LMRRAAFDLAGGYRSLAVAEDSDLYWRLDDIGTLSNIDRNFGSYRVHAGSVSSASIRNGRSMAFWSQMAALSARRRRAGQ
PDQVFSPAELRRCEAAETLEEFFRAGCPGLTQAERSWLALALGMKLVALAFYRPYELDSADCAFIGRALRDRDVAIGREN
RVEIAEHLMATATRLAAHGRFGDALKLVSPARYPVLLGRISFRLVLPSGLRDVFKRLAGRAQPA

Sequences:

>Translated_384_residues
MADPVIDILVPAYNAEPTIREAIDSLRNQTVRNIRIVVVDDGSTDATGRILAEMAAQDGRIVVLTQPNGGIVAALTYGLS
VCRAPFIARHDADDLAAPDRLERQIRHMEEHPDCVAVSGSGSHIDAQGRPTGGRVRLARIDKADPFWIPAREPYLPQPFL
LMRRAAFDLAGGYRSLAVAEDSDLYWRLDDIGTLSNIDRNFGSYRVHAGSVSSASIRNGRSMAFWSQMAALSARRRRAGQ
PDQVFSPAELRRCEAAETLEEFFRAGCPGLTQAERSWLALALGMKLVALAFYRPYELDSADCAFIGRALRDRDVAIGREN
RVEIAEHLMATATRLAAHGRFGDALKLVSPARYPVLLGRISFRLVLPSGLRDVFKRLAGRAQPA
>Mature_383_residues
ADPVIDILVPAYNAEPTIREAIDSLRNQTVRNIRIVVVDDGSTDATGRILAEMAAQDGRIVVLTQPNGGIVAALTYGLSV
CRAPFIARHDADDLAAPDRLERQIRHMEEHPDCVAVSGSGSHIDAQGRPTGGRVRLARIDKADPFWIPAREPYLPQPFLL
MRRAAFDLAGGYRSLAVAEDSDLYWRLDDIGTLSNIDRNFGSYRVHAGSVSSASIRNGRSMAFWSQMAALSARRRRAGQP
DQVFSPAELRRCEAAETLEEFFRAGCPGLTQAERSWLALALGMKLVALAFYRPYELDSADCAFIGRALRDRDVAIGRENR
VEIAEHLMATATRLAAHGRFGDALKLVSPARYPVLLGRISFRLVLPSGLRDVFKRLAGRAQPA

Specific function: Catalyzes the polymerization of chondroitin, a polysaccharide composed of a repeating disaccharide of N- acetylgalactosamine (GalNAc) and glucuronic acid (GlcUA) units. Each unit has the composition in beta-(1->4)-GlcUA-beta-(1->3)- GalNAc [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. CS/HAS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=120, Percent_Identity=34.1666666666667, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212640903, Length=265, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.4.1.175; =2.4.1.226 [H]

Molecular weight: Translated: 42202; Mature: 42070

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPVIDILVPAYNAEPTIREAIDSLRNQTVRNIRIVVVDDGSTDATGRILAEMAAQDGR
CCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCE
IVVLTQPNGGIVAALTYGLSVCRAPFIARHDADDLAAPDRLERQIRHMEEHPDCVAVSGS
EEEEECCCCCEEHHHHHHHHHHHCCHHCCCCCHHCCCCHHHHHHHHHHHCCCCEEEECCC
GSHIDAQGRPTGGRVRLARIDKADPFWIPAREPYLPQPFLLMRRAAFDLAGGYRSLAVAE
CCEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEC
DSDLYWRLDDIGTLSNIDRNFGSYRVHAGSVSSASIRNGRSMAFWSQMAALSARRRRAGQ
CCCCEEEECCCCCHHHHHCCCCCEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCC
PDQVFSPAELRRCEAAETLEEFFRAGCPGLTQAERSWLALALGMKLVALAFYRPYELDSA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DCAFIGRALRDRDVAIGRENRVEIAEHLMATATRLAAHGRFGDALKLVSPARYPVLLGRI
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEE
SFRLVLPSGLRDVFKRLAGRAQPA
EEEEECCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADPVIDILVPAYNAEPTIREAIDSLRNQTVRNIRIVVVDDGSTDATGRILAEMAAQDGR
CCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCE
IVVLTQPNGGIVAALTYGLSVCRAPFIARHDADDLAAPDRLERQIRHMEEHPDCVAVSGS
EEEEECCCCCEEHHHHHHHHHHHCCHHCCCCCHHCCCCHHHHHHHHHHHCCCCEEEECCC
GSHIDAQGRPTGGRVRLARIDKADPFWIPAREPYLPQPFLLMRRAAFDLAGGYRSLAVAE
CCEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEC
DSDLYWRLDDIGTLSNIDRNFGSYRVHAGSVSSASIRNGRSMAFWSQMAALSARRRRAGQ
CCCCEEEECCCCCHHHHHCCCCCEEEECCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCC
PDQVFSPAELRRCEAAETLEEFFRAGCPGLTQAERSWLALALGMKLVALAFYRPYELDSA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DCAFIGRALRDRDVAIGRENRVEIAEHLMATATRLAAHGRFGDALKLVSPARYPVLLGRI
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEE
SFRLVLPSGLRDVFKRLAGRAQPA
EEEEECCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11943778 [H]