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The map label for this gene is xylH [H]

Identifier: 162148315

GI number: 162148315

Start: 2627418

End: 2628641

Strand: Reverse

Name: xylH [H]

Synonym: GDI_2532

Alternate gene names: 162148315

Gene position: 2628641-2627418 (Counterclockwise)

Preceding gene: 162148316

Following gene: 162148312

Centisome position: 66.65

GC content: 63.73

Gene sequence:

>1224_bases
TTGAGACGTATCATGACCATACCCAATACCCCCGTGTCCAGCCCGCCGCATTTCACCGCCGGTATGGCCCAACGGGTCAA
GCTGCTGGACACGGCGCACATCAGGCGCGCCTTTGCGCGATACAAGACGCTGGCGCTTCTGATCGCCATCGCGATCCTGT
GGGGCGTGTTTTCCCACTTCACCGATGGCGATTTCCTGACGGCACGCAATTTCTCGAATCTGCTGCGGCAGATGTCCATT
ACGGGGATGCTCGCCTGCGGGATGGTGTTCGTGATCATTTCCGGGGAAATCGATCTGTCGGTCGGCTCCATGCTCGGGTT
GCTCGGCGGTCTTGCGGCGATCCTGGATGTATCCTTTCATATGCCGCTGGTGTTGAATGTCCTGATCATCATCGTCGCGG
GGGCGGCGATCGGGGCCTTCAACGGATATTGGGTTGCGTATCTGCGCATACCCTCCTTCATCGTCACCCTGGCCGGGTTG
CTGGCGCTGCGCGGCATCCTGCTCGGGATTACCGGTGGCGCGACGATCGCCCCGGTATCGCCGCACCTGGTGGCGGTGGC
GCAGGATTACCTGCCCCCGCTGTTCGGCCGGGGGCTGGAGATCGTCATTCTGGGCATCCTTGCCGCCTCGGCCTTCCAGT
CCCGGGCCAACAGGACGCGCTACAATCTCGCGACGGCGCCCCTGTGGCTCGACATCGTCAAGCTGGCGGGGTCGGCGGCG
GCGATTGTCGCGTTGTTCGCGGCGCTCGATGCCTATCGGGGCGTGCCGCTGCCGGTTCTCGCCATGTTGTTCTTCCTGGC
GATTTTTACCGTCCTGGCGCAGCGGACGACCTTCGGCCGCCGCATCTATGCGATCGGTGGCAACCTGGAAGCCACACGCC
TGTCCGGTGTGAACGTGAAGCTGGTCAAGCTGTCGGTCTTCAGCCTGATGGGCGTGATGGCCGCACTGGCCGGAATCAGT
ACGACGGCCCGGCTGGCGGCGGGCTCGCCTTCCGCCGGATCGCTCCAGGAACTCGACGCGATCGCCGCATGCATTATCGG
CGGCACGTCCATGCGGGGCGGCGCGGGAACGGTCTTCGGGGCGCTGATTGGCGCGCTGATGATGGCGACGCTCGATAACG
GCATGTCGATGCTGGGGGTCGAGGCATACTGGCAGATGATCGTGAAGGGCACGATCCTGTTGGCGGCGGTCTGGCTGGAT
GTCGTGACGAATACGAAGGAGTGA

Upstream 100 bases:

>100_bases
GGGGAAGGGCAGTTGCGCGGCGAATTCATCAACGACGCAACATTGACGCAAGAACGCATCCTGACGGCCGCCATCACGCC
GATCGCGCAAGCCGCGTGAA

Downstream 100 bases:

>100_bases
GAGCGGGTGGGCCTTCCACAATCAGGCACTGTTCCGGCGCGCCGCACGCCGGATCTTCTGCAGCAGTCTCACGCCCTGGG
GGGGCAGGACGTTATGCAGC

Product: xylose ABC transporter permease xylH

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRRIMTIPNTPVSSPPHFTAGMAQRVKLLDTAHIRRAFARYKTLALLIAIAILWGVFSHFTDGDFLTARNFSNLLRQMSI
TGMLACGMVFVIISGEIDLSVGSMLGLLGGLAAILDVSFHMPLVLNVLIIIVAGAAIGAFNGYWVAYLRIPSFIVTLAGL
LALRGILLGITGGATIAPVSPHLVAVAQDYLPPLFGRGLEIVILGILAASAFQSRANRTRYNLATAPLWLDIVKLAGSAA
AIVALFAALDAYRGVPLPVLAMLFFLAIFTVLAQRTTFGRRIYAIGGNLEATRLSGVNVKLVKLSVFSLMGVMAALAGIS
TTARLAAGSPSAGSLQELDAIAACIIGGTSMRGGAGTVFGALIGALMMATLDNGMSMLGVEAYWQMIVKGTILLAAVWLD
VVTNTKE

Sequences:

>Translated_407_residues
MRRIMTIPNTPVSSPPHFTAGMAQRVKLLDTAHIRRAFARYKTLALLIAIAILWGVFSHFTDGDFLTARNFSNLLRQMSI
TGMLACGMVFVIISGEIDLSVGSMLGLLGGLAAILDVSFHMPLVLNVLIIIVAGAAIGAFNGYWVAYLRIPSFIVTLAGL
LALRGILLGITGGATIAPVSPHLVAVAQDYLPPLFGRGLEIVILGILAASAFQSRANRTRYNLATAPLWLDIVKLAGSAA
AIVALFAALDAYRGVPLPVLAMLFFLAIFTVLAQRTTFGRRIYAIGGNLEATRLSGVNVKLVKLSVFSLMGVMAALAGIS
TTARLAAGSPSAGSLQELDAIAACIIGGTSMRGGAGTVFGALIGALMMATLDNGMSMLGVEAYWQMIVKGTILLAAVWLD
VVTNTKE
>Mature_407_residues
MRRIMTIPNTPVSSPPHFTAGMAQRVKLLDTAHIRRAFARYKTLALLIAIAILWGVFSHFTDGDFLTARNFSNLLRQMSI
TGMLACGMVFVIISGEIDLSVGSMLGLLGGLAAILDVSFHMPLVLNVLIIIVAGAAIGAFNGYWVAYLRIPSFIVTLAGL
LALRGILLGITGGATIAPVSPHLVAVAQDYLPPLFGRGLEIVILGILAASAFQSRANRTRYNLATAPLWLDIVKLAGSAA
AIVALFAALDAYRGVPLPVLAMLFFLAIFTVLAQRTTFGRRIYAIGGNLEATRLSGVNVKLVKLSVFSLMGVMAALAGIS
TTARLAAGSPSAGSLQELDAIAACIIGGTSMRGGAGTVFGALIGALMMATLDNGMSMLGVEAYWQMIVKGTILLAAVWLD
VVTNTKE

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=369, Percent_Identity=53.6585365853659, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1790191, Length=381, Percent_Identity=37.7952755905512, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788896, Length=379, Percent_Identity=30.8707124010554, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790524, Length=386, Percent_Identity=32.6424870466321, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI145693152, Length=365, Percent_Identity=30.4109589041096, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082395, Length=331, Percent_Identity=31.1178247734139, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787793, Length=342, Percent_Identity=29.8245614035088, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788471, Length=378, Percent_Identity=31.2169312169312, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787794, Length=152, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 42776; Mature: 42776

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIMTIPNTPVSSPPHFTAGMAQRVKLLDTAHIRRAFARYKTLALLIAIAILWGVFSHF
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDGDFLTARNFSNLLRQMSITGMLACGMVFVIISGEIDLSVGSMLGLLGGLAAILDVSFH
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCC
MPLVLNVLIIIVAGAAIGAFNGYWVAYLRIPSFIVTLAGLLALRGILLGITGGATIAPVS
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCC
PHLVAVAQDYLPPLFGRGLEIVILGILAASAFQSRANRTRYNLATAPLWLDIVKLAGSAA
CHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHCCHH
AIVALFAALDAYRGVPLPVLAMLFFLAIFTVLAQRTTFGRRIYAIGGNLEATRLSGVNVK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCEEE
LVKLSVFSLMGVMAALAGISTTARLAAGSPSAGSLQELDAIAACIIGGTSMRGGAGTVFG
EHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHH
ALIGALMMATLDNGMSMLGVEAYWQMIVKGTILLAAVWLDVVTNTKE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRIMTIPNTPVSSPPHFTAGMAQRVKLLDTAHIRRAFARYKTLALLIAIAILWGVFSHF
CCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDGDFLTARNFSNLLRQMSITGMLACGMVFVIISGEIDLSVGSMLGLLGGLAAILDVSFH
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCC
MPLVLNVLIIIVAGAAIGAFNGYWVAYLRIPSFIVTLAGLLALRGILLGITGGATIAPVS
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCC
PHLVAVAQDYLPPLFGRGLEIVILGILAASAFQSRANRTRYNLATAPLWLDIVKLAGSAA
CHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHHCCHH
AIVALFAALDAYRGVPLPVLAMLFFLAIFTVLAQRTTFGRRIYAIGGNLEATRLSGVNVK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCEEE
LVKLSVFSLMGVMAALAGISTTARLAAGSPSAGSLQELDAIAACIIGGTSMRGGAGTVFG
EHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHH
ALIGALMMATLDNGMSMLGVEAYWQMIVKGTILLAAVWLDVVTNTKE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]