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The map label for this gene is ade [H]

Identifier: 162148309

GI number: 162148309

Start: 2619864

End: 2621573

Strand: Direct

Name: ade [H]

Synonym: GDI_2526

Alternate gene names: 162148309

Gene position: 2619864-2621573 (Clockwise)

Preceding gene: 162148308

Following gene: 162148310

Centisome position: 66.42

GC content: 68.13

Gene sequence:

>1710_bases
ATGAGCAGGACATCGCCCGACATCATCGCCCGCCGCATCCGCCAGGGAAGTGGACAGGAACCGCCTGACCTGGTGGTCCG
CGACGTCCGCCTGTTCGACCTGGTCACCGGCGACCTGATCCCGACCGACATCGCGATCTGCGGCGATACCATCGTCGGCA
TGCTGGACCGCTACCAGGGACCGAACGTGATCGAGGGGAACGGGCGCGTCGTCGTTCCCGGTTTCATCGACACCCACCTG
CATGTCGAATCGTCGCTGGTCACGCCATTCGAATTCGAACGCTGCGTGCTGCCGCACGGGGTAACGACCGCGATCTGCGA
CCCGCACGAAATGGCCAACGTGCTGGGCACCGACGCATTGCGCTATTTCCTGGACGCCGCGACGCGCATGGTCATGGACC
TGCGGGTCAACCTGTCCAGTTGCGTGCCGTCCTCCTCGGTCGAGACCTCGGGCGCGAACCTGGGCGCCGATGACCTGACG
CCCCTGATGGACCACCCCAAGGTCATCGGACTGGCGGAAGTCATGAACATGCCCGGCGTACTGGCCGGCGATCCGGATTG
CCTGGCCAAGCTGGCGGCATTCTCGGGCCGGCATATCGACGGGCATGCGCCGCTGATGCGCGGCCGCGCGCTGAACGGCT
ACCTGGCGGCCGGTATTTCCACCGACCACGAAGCCACCCGCGCCGACGAGGCGCTGGAAAAGATCCGCAAGGGCATGACC
GTGCTGATCCGCGAGGGATCGGTCTGCAAGGATCTGGCGGCGCTGGCCCCGCTGCTGACGGTCGAGACGTCGCCCTTCCT
GGCCTTCTGTACCGACGACCGCAATCCGCTGGAAATCGCGCATGAGGGGCATATCGATTTCCTGATCCGCAGCGCGATCG
CGCGCGGCGTTCCGCCGCTGGCGGCCTATCGCGCCGCCAGCCTGACGGCGGCGCGCGCCTTCGGGCTGGCCGATCGCGGC
ATGCTGGCCCCGGGCCGGCGCGCCGACATCGTGTTCCTGGACGACCTGGAAACCTGCCAGGTCTCGGACGTTCTGGCCGG
CGGCCGGCCGATCGGTCCGGCCCTGGAGCAGCGCCGGACGATTCCGGCGCCGGGGCGCGACAGCGTGATCCTGCGGCGCC
CGGTCACGGCGGAGGATTTCACGGTTTCGGGGTCCGGGACCGGTCACCCGGTCATGGGCATCATCCCGGGCCAGATCATC
ACCGATTTCCTGACCCTGGACCTGTCGGCGCGGCACGGCAGGGTCGAAGCCGATTGCGACCGGGACGTGGCCAAGGTTGC
CGTGGTGGCGCGGCATGGGCTGAACGGGAATATCGGCCGGGGCTTCGTCCGGGGCTTCGGATTGCGGCGCGGGGCGCTGG
CGTCCTCGGTCGGGCACGATGCCCATAATATCTGCGTCGTCGGCGCCGATGACGGCGACATGGCCGTCGCGGTCAATCGC
CTGGCCGAAATCGGCGGCGGCTTCGTGATCGTCCAGGACGGGCAGGTGCGCGCGGAACTGCCCCTGCCGATCGCCGGGCT
GATGAGCGATGCACCGTTCGAGACCGTGCGCGACCAGTTGGAGACCCTGCGCGCGGCAACCCGCGCCATGGGCGTGACGC
TGGAAGAACCGTTCCTGCAACTGGCCTTCCTGCCGCTGCCGGTCGTGCCGCATCTGAAGATCACCGATCACGGACTGGTC
GATGTCGGGCAAATGCGGGTGATCGGCTGA

Upstream 100 bases:

>100_bases
CTGGCAGGGGGTGCCGCGCTGTGGGCCATGCCCGGCGCGAAACGGGACCTGACGCGGACGTGCCATGGACGGGAATCCCC
CTTCCATGCATAAAAATACC

Downstream 100 bases:

>100_bases
TCCACCGCCCCGGCGGCGGCATCGTGGAATAGTTCAACCTGTTGCAGATTCCGCCCCGGGCTCTTCATCACAGTTTGTCG
TCTTCGGAAATACAACGACA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSRTSPDIIARRIRQGSGQEPPDLVVRDVRLFDLVTGDLIPTDIAICGDTIVGMLDRYQGPNVIEGNGRVVVPGFIDTHL
HVESSLVTPFEFERCVLPHGVTTAICDPHEMANVLGTDALRYFLDAATRMVMDLRVNLSSCVPSSSVETSGANLGADDLT
PLMDHPKVIGLAEVMNMPGVLAGDPDCLAKLAAFSGRHIDGHAPLMRGRALNGYLAAGISTDHEATRADEALEKIRKGMT
VLIREGSVCKDLAALAPLLTVETSPFLAFCTDDRNPLEIAHEGHIDFLIRSAIARGVPPLAAYRAASLTAARAFGLADRG
MLAPGRRADIVFLDDLETCQVSDVLAGGRPIGPALEQRRTIPAPGRDSVILRRPVTAEDFTVSGSGTGHPVMGIIPGQII
TDFLTLDLSARHGRVEADCDRDVAKVAVVARHGLNGNIGRGFVRGFGLRRGALASSVGHDAHNICVVGADDGDMAVAVNR
LAEIGGGFVIVQDGQVRAELPLPIAGLMSDAPFETVRDQLETLRAATRAMGVTLEEPFLQLAFLPLPVVPHLKITDHGLV
DVGQMRVIG

Sequences:

>Translated_569_residues
MSRTSPDIIARRIRQGSGQEPPDLVVRDVRLFDLVTGDLIPTDIAICGDTIVGMLDRYQGPNVIEGNGRVVVPGFIDTHL
HVESSLVTPFEFERCVLPHGVTTAICDPHEMANVLGTDALRYFLDAATRMVMDLRVNLSSCVPSSSVETSGANLGADDLT
PLMDHPKVIGLAEVMNMPGVLAGDPDCLAKLAAFSGRHIDGHAPLMRGRALNGYLAAGISTDHEATRADEALEKIRKGMT
VLIREGSVCKDLAALAPLLTVETSPFLAFCTDDRNPLEIAHEGHIDFLIRSAIARGVPPLAAYRAASLTAARAFGLADRG
MLAPGRRADIVFLDDLETCQVSDVLAGGRPIGPALEQRRTIPAPGRDSVILRRPVTAEDFTVSGSGTGHPVMGIIPGQII
TDFLTLDLSARHGRVEADCDRDVAKVAVVARHGLNGNIGRGFVRGFGLRRGALASSVGHDAHNICVVGADDGDMAVAVNR
LAEIGGGFVIVQDGQVRAELPLPIAGLMSDAPFETVRDQLETLRAATRAMGVTLEEPFLQLAFLPLPVVPHLKITDHGLV
DVGQMRVIG
>Mature_568_residues
SRTSPDIIARRIRQGSGQEPPDLVVRDVRLFDLVTGDLIPTDIAICGDTIVGMLDRYQGPNVIEGNGRVVVPGFIDTHLH
VESSLVTPFEFERCVLPHGVTTAICDPHEMANVLGTDALRYFLDAATRMVMDLRVNLSSCVPSSSVETSGANLGADDLTP
LMDHPKVIGLAEVMNMPGVLAGDPDCLAKLAAFSGRHIDGHAPLMRGRALNGYLAAGISTDHEATRADEALEKIRKGMTV
LIREGSVCKDLAALAPLLTVETSPFLAFCTDDRNPLEIAHEGHIDFLIRSAIARGVPPLAAYRAASLTAARAFGLADRGM
LAPGRRADIVFLDDLETCQVSDVLAGGRPIGPALEQRRTIPAPGRDSVILRRPVTAEDFTVSGSGTGHPVMGIIPGQIIT
DFLTLDLSARHGRVEADCDRDVAKVAVVARHGLNGNIGRGFVRGFGLRRGALASSVGHDAHNICVVGADDGDMAVAVNRL
AEIGGGFVIVQDGQVRAELPLPIAGLMSDAPFETVRDQLETLRAATRAMGVTLEEPFLQLAFLPLPVVPHLKITDHGLVD
VGQMRVIG

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=553, Percent_Identity=43.3996383363472, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 60501; Mature: 60370

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTSPDIIARRIRQGSGQEPPDLVVRDVRLFDLVTGDLIPTDIAICGDTIVGMLDRYQG
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
PNVIEGNGRVVVPGFIDTHLHVESSLVTPFEFERCVLPHGVTTAICDPHEMANVLGTDAL
CCEEECCCEEEECCEECCEEEECCCCCCCCCCCCEECCCCCEEEECCHHHHHHHHHHHHH
RYFLDAATRMVMDLRVNLSSCVPSSSVETSGANLGADDLTPLMDHPKVIGLAEVMNMPGV
HHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEHHHHHCCCCC
LAGDPDCLAKLAAFSGRHIDGHAPLMRGRALNGYLAAGISTDHEATRADEALEKIRKGMT
CCCCHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCE
VLIREGSVCKDLAALAPLLTVETSPFLAFCTDDRNPLEIAHEGHIDFLIRSAIARGVPPL
EEEECCCHHHHHHHHHHHHEECCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCH
AAYRAASLTAARAFGLADRGMLAPGRRADIVFLDDLETCQVSDVLAGGRPIGPALEQRRT
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCCHHHHHCCC
IPAPGRDSVILRRPVTAEDFTVSGSGTGHPVMGIIPGQIITDFLTLDLSARHGRVEADCD
CCCCCCCCEEEECCCCCCCEEECCCCCCCCEEEEECHHHHHHHHHEECCCCCCCCCCCCC
RDVAKVAVVARHGLNGNIGRGFVRGFGLRRGALASSVGHDAHNICVVGADDGDMAVAVNR
HHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHHH
LAEIGGGFVIVQDGQVRAELPLPIAGLMSDAPFETVRDQLETLRAATRAMGVTLEEPFLQ
HHHHCCCEEEEECCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEECCHHHH
LAFLPLPVVPHLKITDHGLVDVGQMRVIG
HHHCCCCCCCCEEECCCCCEECCCEEECC
>Mature Secondary Structure 
SRTSPDIIARRIRQGSGQEPPDLVVRDVRLFDLVTGDLIPTDIAICGDTIVGMLDRYQG
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
PNVIEGNGRVVVPGFIDTHLHVESSLVTPFEFERCVLPHGVTTAICDPHEMANVLGTDAL
CCEEECCCEEEECCEECCEEEECCCCCCCCCCCCEECCCCCEEEECCHHHHHHHHHHHHH
RYFLDAATRMVMDLRVNLSSCVPSSSVETSGANLGADDLTPLMDHPKVIGLAEVMNMPGV
HHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEHHHHHCCCCC
LAGDPDCLAKLAAFSGRHIDGHAPLMRGRALNGYLAAGISTDHEATRADEALEKIRKGMT
CCCCHHHHHHHHHHCCCCCCCCCCHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCE
VLIREGSVCKDLAALAPLLTVETSPFLAFCTDDRNPLEIAHEGHIDFLIRSAIARGVPPL
EEEECCCHHHHHHHHHHHHEECCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCH
AAYRAASLTAARAFGLADRGMLAPGRRADIVFLDDLETCQVSDVLAGGRPIGPALEQRRT
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCCCCHHHHHCCC
IPAPGRDSVILRRPVTAEDFTVSGSGTGHPVMGIIPGQIITDFLTLDLSARHGRVEADCD
CCCCCCCCEEEECCCCCCCEEECCCCCCCCEEEEECHHHHHHHHHEECCCCCCCCCCCCC
RDVAKVAVVARHGLNGNIGRGFVRGFGLRRGALASSVGHDAHNICVVGADDGDMAVAVNR
HHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCEEEEECCCCCHHHHHHH
LAEIGGGFVIVQDGQVRAELPLPIAGLMSDAPFETVRDQLETLRAATRAMGVTLEEPFLQ
HHHHCCCEEEEECCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEECCHHHH
LAFLPLPVVPHLKITDHGLVDVGQMRVIG
HHHCCCCCCCCEEECCCCCEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA