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The map label for this gene is nuoH [H]

Identifier: 162148248

GI number: 162148248

Start: 2554292

End: 2555248

Strand: Reverse

Name: nuoH [H]

Synonym: GDI_2465

Alternate gene names: 162148248

Gene position: 2555248-2554292 (Counterclockwise)

Preceding gene: 162148249

Following gene: 162148247

Centisome position: 64.79

GC content: 67.4

Gene sequence:

>957_bases
ATGATCGTTCCCATGCCCGCCATCATTGCCGTCACGCTGGTGGTCCTGCTGGGGCTGGCGACGGCGCTGACGTGGGTCGA
GCGGCGCCTGCTGGGCGTGTGGCAGGACCGCTACGGGCCCAACCGCGTCGGGCCCGGCGGCGTTCTGCAGGCCGTGGCCG
ACGGCATCAAGATCCTGTTCAAGCAGGACTGGATTCCGCCGTTCGCCGACCGGGCCGTGTTCGTCCTGGCGCCGACCATC
GGCATGATGACGGTGCTGCTGTCCTTCGCGGTCATCCCCGTCACCGCGTGGTGGAGCGTCGCCGCCGGGCTGAATGTCGG
GCTGCTGTTCGTCTTCGCCGCCATGGGGATGGGGGTCTATTCCGTGGTGCTGGCGGGCTGGGCGTCGAACAGCAAATACG
CCCTGCTGGGCGGGCTGCGGGCGGCGGCGCAGATGATCAGCTACGAAGTGTTCATGGGCCTGTCCGCCCTGGGCGTGGTC
ATGGCGGCGCATTCGTTCAGCCTGCGCGACATCGTGCTGGCGCAGTCGGGCCTGTGGTTCGTCATCCCGCAGGCACTGGG
CTGCGTCGTGTTCCTGCTGGCCGGAATCGCGGAAACCCATCGCCTGCCGTTCGATCTTCCGGAAGGCGAGAACGAACTGG
GGGCCGGATTCCATACCGAATATTCGGGCATGAAGTTCGGCATGTTCTTCCTGGCGGAATATGCGGGCATCGTCCTGATC
TCGGCCCTGGTGGCGACGTTGTACCTGGGCGGATGGCAGGGGCCGGTCCTGCCCGGGGGGCTGTGGTTCGCGCTGAAGAC
CGGGGTGCTGACCGGCCTGTTCATCCTGCTGCGCGCGGCGCTGCCGCGCCTGCGCTACGACCAGTTGATGGTGCTGGGCT
GGAAGGTCCTGCTGCCGCTTTCCTTGCTCAATATCGTTGCGACCGGCGCGGTGCTGCTGCTGCGCGCGCCGGGATAG

Upstream 100 bases:

>100_bases
TGCCGCCCGGGGTCGCGCTGTGTCCGGCGCATGCGGGCGGGGCGCAGGGTATCGTCAGTCCCGTCTGGGCCGATATCGGG
CATGCGGGCGGGGACGCGTC

Downstream 100 bases:

>100_bases
GGGGCCCGCGATGTTCGATATCCTGCGCACGCTGTGGCTGACCTTCCGGCACATGACCCATCGCCGGGTCACGGTGGGCT
ATCCCGAGACCAAGCCGCCG

Product: NADH-quinone oxidoreductase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIVPMPAIIAVTLVVLLGLATALTWVERRLLGVWQDRYGPNRVGPGGVLQAVADGIKILFKQDWIPPFADRAVFVLAPTI
GMMTVLLSFAVIPVTAWWSVAAGLNVGLLFVFAAMGMGVYSVVLAGWASNSKYALLGGLRAAAQMISYEVFMGLSALGVV
MAAHSFSLRDIVLAQSGLWFVIPQALGCVVFLLAGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFLAEYAGIVLI
SALVATLYLGGWQGPVLPGGLWFALKTGVLTGLFILLRAALPRLRYDQLMVLGWKVLLPLSLLNIVATGAVLLLRAPG

Sequences:

>Translated_318_residues
MIVPMPAIIAVTLVVLLGLATALTWVERRLLGVWQDRYGPNRVGPGGVLQAVADGIKILFKQDWIPPFADRAVFVLAPTI
GMMTVLLSFAVIPVTAWWSVAAGLNVGLLFVFAAMGMGVYSVVLAGWASNSKYALLGGLRAAAQMISYEVFMGLSALGVV
MAAHSFSLRDIVLAQSGLWFVIPQALGCVVFLLAGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFLAEYAGIVLI
SALVATLYLGGWQGPVLPGGLWFALKTGVLTGLFILLRAALPRLRYDQLMVLGWKVLLPLSLLNIVATGAVLLLRAPG
>Mature_318_residues
MIVPMPAIIAVTLVVLLGLATALTWVERRLLGVWQDRYGPNRVGPGGVLQAVADGIKILFKQDWIPPFADRAVFVLAPTI
GMMTVLLSFAVIPVTAWWSVAAGLNVGLLFVFAAMGMGVYSVVLAGWASNSKYALLGGLRAAAQMISYEVFMGLSALGVV
MAAHSFSLRDIVLAQSGLWFVIPQALGCVVFLLAGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFLAEYAGIVLI
SALVATLYLGGWQGPVLPGGLWFALKTGVLTGLFILLRAALPRLRYDQLMVLGWKVLLPLSLLNIVATGAVLLLRAPG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=279, Percent_Identity=41.9354838709677, Blast_Score=213, Evalue=2e-55,
Organism=Escherichia coli, GI1788618, Length=306, Percent_Identity=56.8627450980392, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI1789077, Length=307, Percent_Identity=30.2931596091205, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 33970; Mature: 33970

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVPMPAIIAVTLVVLLGLATALTWVERRLLGVWQDRYGPNRVGPGGVLQAVADGIKILF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
KQDWIPPFADRAVFVLAPTIGMMTVLLSFAVIPVTAWWSVAAGLNVGLLFVFAAMGMGVY
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVVLAGWASNSKYALLGGLRAAAQMISYEVFMGLSALGVVMAAHSFSLRDIVLAQSGLWF
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEE
VIPQALGCVVFLLAGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFLAEYAGIVLI
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SALVATLYLGGWQGPVLPGGLWFALKTGVLTGLFILLRAALPRLRYDQLMVLGWKVLLPL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SLLNIVATGAVLLLRAPG
HHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MIVPMPAIIAVTLVVLLGLATALTWVERRLLGVWQDRYGPNRVGPGGVLQAVADGIKILF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
KQDWIPPFADRAVFVLAPTIGMMTVLLSFAVIPVTAWWSVAAGLNVGLLFVFAAMGMGVY
HHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SVVLAGWASNSKYALLGGLRAAAQMISYEVFMGLSALGVVMAAHSFSLRDIVLAQSGLWF
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEE
VIPQALGCVVFLLAGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFLAEYAGIVLI
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
SALVATLYLGGWQGPVLPGGLWFALKTGVLTGLFILLRAALPRLRYDQLMVLGWKVLLPL
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SLLNIVATGAVLLLRAPG
HHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA