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The map label for this gene is cusB [H]

Identifier: 162148220

GI number: 162148220

Start: 2523735

End: 2524877

Strand: Direct

Name: cusB [H]

Synonym: GDI_2437

Alternate gene names: 162148220

Gene position: 2523735-2524877 (Clockwise)

Preceding gene: 162148215

Following gene: 162148221

Centisome position: 63.99

GC content: 70.6

Gene sequence:

>1143_bases
ATGCTCCACATCATGCCCCCGACCATTTCCGGGCCAGCCACCGGGTCAATCGCCGCCTGGGGCCTGGCGGCCCTCCTCCT
GGCCGCGACCGTGGCCGCGCCGTCGGCCGCCCGGGCCGAGAATACCACCATGATCCGGGACGATCACGGCCGCCTGACGG
TTCCGGAAAATTCCCCCATGGCGGCCCGCCTGGCCGTCGCCCCGGTCACGCTGACGAAACCCAGCCGCGCTATTCCCGTC
CCCGGCGCGATCATGGCCGAACCCGCGCGCTCGATTTCCGTGCAGGCACCGCTGGCAGGGCATATCGTCAGCCTGCCGGT
GGCCCCGGGTGATCACGTGACGCGCGGGCAGGTCGTGGCCGAACTGCTTTCGGGCGACATGGCGCAGGCCACGACCGACG
AGGTCAAGGCCCGGGCGGCGCTCGACCTCGCCCGCCGCGCGCTGACCCGTGCCCAGGGCGTGGCGCAGGCCGGCGGCGGT
GCCGTGCGCGACATCGAAGCCGCCCGCAGCACGTACCTGCAGGCCGTGGCCGAGGACGACCGCGCCACCGCCCGTCTGGC
GGCATTGGGCGGCCAGCCGGGCGGCGGCGGCACGATGAAGCTGGTCTCGCCGGTCGATGGCGTGGTTTCGACGGTCAATA
CCGCCGCCGGCGCCAACGTCACGGACCCGACCGCGCCGCTGCTGACGATCGCGGACACGCGGGAAGTCTGGGCCGTGGCC
AACGTGCCGGAAAACGAGGTCGCGACCATCCAGGCCGGCCAGCAGGCCGACATCTACGTTCCCGGCCTGCCGGGCGAGGT
GCTGCATGGCGCCATCGCGGCGATCGAACCGACGCTGCACGCGGATACGCGCACCCTGCAGGCCCGCGTGGTACTGCCCA
ACGCGGACGGCGCGCTGAAGCCCAACATGTTCGCGACCGTGACGGTGGAAGCCCCGCAATCCCCCCGCATCATGGTCCCG
CAATCGGCGCTGCTGATGAACAACGACACGGTCACGGTGTTCGTCGAGGTCGCCCCACACACCTACATGCGTCGGAATAT
CGATATCATCTATGACGACGGCGACCTGTGCGAGGTCGATTCCGGCCTGTCGGCGGGCGAGCGGATCGTCACCCAGGGCG
CGGTGCTGCTGAACGATGATTAA

Upstream 100 bases:

>100_bases
GGTCCCGAAGCCTGGGGCCCCGATCCTTTTCTCCATCAGATGCGCCGGCACCCGCACGACACGGGGGTGCCAGACGGCCG
GGACAACCAGACACCAGACC

Downstream 100 bases:

>100_bases
CCAGTTCATCGCGATCTGCCTGCGGCAGCGGCGCATCGTCTTTGCCGCCATGGCCGTGCTGGTCGCTCTGGGTGCCCTGG
CGTGGCACCAGATCCCGGTC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MLHIMPPTISGPATGSIAAWGLAALLLAATVAAPSAARAENTTMIRDDHGRLTVPENSPMAARLAVAPVTLTKPSRAIPV
PGAIMAEPARSISVQAPLAGHIVSLPVAPGDHVTRGQVVAELLSGDMAQATTDEVKARAALDLARRALTRAQGVAQAGGG
AVRDIEAARSTYLQAVAEDDRATARLAALGGQPGGGGTMKLVSPVDGVVSTVNTAAGANVTDPTAPLLTIADTREVWAVA
NVPENEVATIQAGQQADIYVPGLPGEVLHGAIAAIEPTLHADTRTLQARVVLPNADGALKPNMFATVTVEAPQSPRIMVP
QSALLMNNDTVTVFVEVAPHTYMRRNIDIIYDDGDLCEVDSGLSAGERIVTQGAVLLNDD

Sequences:

>Translated_380_residues
MLHIMPPTISGPATGSIAAWGLAALLLAATVAAPSAARAENTTMIRDDHGRLTVPENSPMAARLAVAPVTLTKPSRAIPV
PGAIMAEPARSISVQAPLAGHIVSLPVAPGDHVTRGQVVAELLSGDMAQATTDEVKARAALDLARRALTRAQGVAQAGGG
AVRDIEAARSTYLQAVAEDDRATARLAALGGQPGGGGTMKLVSPVDGVVSTVNTAAGANVTDPTAPLLTIADTREVWAVA
NVPENEVATIQAGQQADIYVPGLPGEVLHGAIAAIEPTLHADTRTLQARVVLPNADGALKPNMFATVTVEAPQSPRIMVP
QSALLMNNDTVTVFVEVAPHTYMRRNIDIIYDDGDLCEVDSGLSAGERIVTQGAVLLNDD
>Mature_380_residues
MLHIMPPTISGPATGSIAAWGLAALLLAATVAAPSAARAENTTMIRDDHGRLTVPENSPMAARLAVAPVTLTKPSRAIPV
PGAIMAEPARSISVQAPLAGHIVSLPVAPGDHVTRGQVVAELLSGDMAQATTDEVKARAALDLARRALTRAQGVAQAGGG
AVRDIEAARSTYLQAVAEDDRATARLAALGGQPGGGGTMKLVSPVDGVVSTVNTAAGANVTDPTAPLLTIADTREVWAVA
NVPENEVATIQAGQQADIYVPGLPGEVLHGAIAAIEPTLHADTRTLQARVVLPNADGALKPNMFATVTVEAPQSPRIMVP
QSALLMNNDTVTVFVEVAPHTYMRRNIDIIYDDGDLCEVDSGLSAGERIVTQGAVLLNDD

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=182, Percent_Identity=27.4725274725275, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082036, Length=300, Percent_Identity=24.3333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081796, Length=256, Percent_Identity=27.734375, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39069; Mature: 39069

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHIMPPTISGPATGSIAAWGLAALLLAATVAAPSAARAENTTMIRDDHGRLTVPENSPM
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEECCCCCCC
AARLAVAPVTLTKPSRAIPVPGAIMAEPARSISVQAPLAGHIVSLPVAPGDHVTRGQVVA
EEEEEEEEEEECCCCCCCCCCCHHHCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHH
ELLSGDMAQATTDEVKARAALDLARRALTRAQGVAQAGGGAVRDIEAARSTYLQAVAEDD
HHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
RATARLAALGGQPGGGGTMKLVSPVDGVVSTVNTAAGANVTDPTAPLLTIADTREVWAVA
HHHEEHEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEE
NVPENEVATIQAGQQADIYVPGLPGEVLHGAIAAIEPTLHADTRTLQARVVLPNADGALK
CCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCC
PNMFATVTVEAPQSPRIMVPQSALLMNNDTVTVFVEVAPHTYMRRNIDIIYDDGDLCEVD
CCEEEEEEEECCCCCEEECCCCEEEECCCEEEEEEEECCCCCHHCCCEEEECCCCEEEEC
SGLSAGERIVTQGAVLLNDD
CCCCCCCCEECCCEEEEECC
>Mature Secondary Structure
MLHIMPPTISGPATGSIAAWGLAALLLAATVAAPSAARAENTTMIRDDHGRLTVPENSPM
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEECCCCCCC
AARLAVAPVTLTKPSRAIPVPGAIMAEPARSISVQAPLAGHIVSLPVAPGDHVTRGQVVA
EEEEEEEEEEECCCCCCCCCCCHHHCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHH
ELLSGDMAQATTDEVKARAALDLARRALTRAQGVAQAGGGAVRDIEAARSTYLQAVAEDD
HHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
RATARLAALGGQPGGGGTMKLVSPVDGVVSTVNTAAGANVTDPTAPLLTIADTREVWAVA
HHHEEHEECCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEE
NVPENEVATIQAGQQADIYVPGLPGEVLHGAIAAIEPTLHADTRTLQARVVLPNADGALK
CCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCC
PNMFATVTVEAPQSPRIMVPQSALLMNNDTVTVFVEVAPHTYMRRNIDIIYDDGDLCEVD
CCEEEEEEEECCCCCEEECCCCEEEECCCEEEEEEEECCCCCHHCCCEEEECCCCEEEEC
SGLSAGERIVTQGAVLLNDD
CCCCCCCCEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]