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The map label for this gene is ltaE [H]

Identifier: 162148211

GI number: 162148211

Start: 2514543

End: 2515583

Strand: Direct

Name: ltaE [H]

Synonym: GDI_2428

Alternate gene names: 162148211

Gene position: 2514543-2515583 (Clockwise)

Preceding gene: 162148210

Following gene: 162148212

Centisome position: 63.75

GC content: 66.76

Gene sequence:

>1041_bases
ATGCCCCAGACGCAGCAGTTCGCCAGCGACAATTACGCCGGTATCTGTCCCGAAGCCCTGCGTGCGATGGAAGACGCCAA
TCGCGGGTCCGCCCAGGCCTATGGTGACGATCCCTGGACGGTCCGCGCGGCCGATGCGTTTCGCGCGACCTTCGAGACCG
ATTGCGAGCTGTTCTTCGTCTTCAACGGCACGGCCGCCAATTCGCTGGCCCTGGCCGCGCTGTGCCAGTCGTACGAAAGC
ATCATCGCCGCCGACATCGCCCATGTCGAAACCGACGAATGCGGGGCGCCGGAATTCTTTTCCAACGGCGCCAAGATCCT
GGTCGGGCGGACCGAAAACGGCAAGCTGACGCCGGAGACGATCCGCGGCTTCGCGCGGGGACGCACCGACATCCATTTCC
CGCGTCCGCGCGCCGTCACCATCACCCAGCCCACCGAGACCGGCCAGGTCTACAGCCTGGAGGAAATCCGCGCCGTCGCC
GCCACCTGCCGCGAACTGGGGCTGAAGCTGCATATGGATGGCGCGCGATTCGCCAATGCCGTCGAAAGCCTGGGCTGCAC
CCCGGCCGATATGACGTGGCGTTCCGGGGTGGACGTGCTGAGCTTCGGCGGCACCAAGAACGGCATGGCGATCGGCGAGG
CGGTGATCTTCTTCAACCGCTCCCTGGCCGAAGGGTTCGATTATCGCTGCAAGCAGGCCGGCCAACTGGCATCCAAGATG
CGCTTCCTGTCCGCGCCCTGGGCCGTGATGTTCGAAACCGGCGCATGGCGCGCGAATGCCGCCCATGCCAATGCCTGCGC
CCGTCACTTCGCCGATCAGGTCGCGGACCTGCCGGGGGTGGAGGTGCAGTTTCCCGTCGAGGCGAACGCGGTATTCCTGA
AGCTGCCCCCCGAGACGACCGCGGCGCTGCGGGCGCGCGGCTGGCTGTTCTATACCTTCATCGGTGACAGCGCCCGCTTC
ATGTTCGCCTGGGATTCGGAGCGTGCGCGCATCGACGCGCTGGCGGCGGACCTGCGCGCCATCACCCGCACGCCGGCATG
A

Upstream 100 bases:

>100_bases
GTGACGGGAAGATGTGGCCGATCCGGCAAAAAACGGACCCCAGCCGCACGCCATGATCCTCGCGATGCGCGACATCGGAC
GAGGAAAGGCCTTTACCGCA

Downstream 100 bases:

>100_bases
CGCTGCAATCCTGGCTGCTCTACCTGAACGCAGTGTTCCTGCTGTCGGCCATTCCCGGGCCGAACATGACGCACATCATG
ACCGTCAGCGTCCGAAACGG

Product: low specificity L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MPQTQQFASDNYAGICPEALRAMEDANRGSAQAYGDDPWTVRAADAFRATFETDCELFFVFNGTAANSLALAALCQSYES
IIAADIAHVETDECGAPEFFSNGAKILVGRTENGKLTPETIRGFARGRTDIHFPRPRAVTITQPTETGQVYSLEEIRAVA
ATCRELGLKLHMDGARFANAVESLGCTPADMTWRSGVDVLSFGGTKNGMAIGEAVIFFNRSLAEGFDYRCKQAGQLASKM
RFLSAPWAVMFETGAWRANAAHANACARHFADQVADLPGVEVQFPVEANAVFLKLPPETTAALRARGWLFYTFIGDSARF
MFAWDSERARIDALAADLRAITRTPA

Sequences:

>Translated_346_residues
MPQTQQFASDNYAGICPEALRAMEDANRGSAQAYGDDPWTVRAADAFRATFETDCELFFVFNGTAANSLALAALCQSYES
IIAADIAHVETDECGAPEFFSNGAKILVGRTENGKLTPETIRGFARGRTDIHFPRPRAVTITQPTETGQVYSLEEIRAVA
ATCRELGLKLHMDGARFANAVESLGCTPADMTWRSGVDVLSFGGTKNGMAIGEAVIFFNRSLAEGFDYRCKQAGQLASKM
RFLSAPWAVMFETGAWRANAAHANACARHFADQVADLPGVEVQFPVEANAVFLKLPPETTAALRARGWLFYTFIGDSARF
MFAWDSERARIDALAADLRAITRTPA
>Mature_345_residues
PQTQQFASDNYAGICPEALRAMEDANRGSAQAYGDDPWTVRAADAFRATFETDCELFFVFNGTAANSLALAALCQSYESI
IAADIAHVETDECGAPEFFSNGAKILVGRTENGKLTPETIRGFARGRTDIHFPRPRAVTITQPTETGQVYSLEEIRAVAA
TCRELGLKLHMDGARFANAVESLGCTPADMTWRSGVDVLSFGGTKNGMAIGEAVIFFNRSLAEGFDYRCKQAGQLASKMR
FLSAPWAVMFETGAWRANAAHANACARHFADQVADLPGVEVQFPVEANAVFLKLPPETTAALRARGWLFYTFIGDSARFM
FAWDSERARIDALAADLRAITRTPA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=324, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320789, Length=290, Percent_Identity=27.9310344827586, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37653; Mature: 37521

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQTQQFASDNYAGICPEALRAMEDANRGSAQAYGDDPWTVRAADAFRATFETDCELFFV
CCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCEEEEE
FNGTAANSLALAALCQSYESIIAADIAHVETDECGAPEFFSNGAKILVGRTENGKLTPET
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHH
IRGFARGRTDIHFPRPRAVTITQPTETGQVYSLEEIRAVAATCRELGLKLHMDGARFANA
HHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCEEEECHHHHHHH
VESLGCTPADMTWRSGVDVLSFGGTKNGMAIGEAVIFFNRSLAEGFDYRCKQAGQLASKM
HHHHCCCCCCCCHHCCCCEEEECCCCCCCHHHHEEEEECCHHHHCCCHHHHHHHHHHHHH
RFLSAPWAVMFETGAWRANAAHANACARHFADQVADLPGVEVQFPVEANAVFLKLPPETT
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHH
AALRARGWLFYTFIGDSARFMFAWDSERARIDALAADLRAITRTPA
HHHHHCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PQTQQFASDNYAGICPEALRAMEDANRGSAQAYGDDPWTVRAADAFRATFETDCELFFV
CCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCEEEEE
FNGTAANSLALAALCQSYESIIAADIAHVETDECGAPEFFSNGAKILVGRTENGKLTPET
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECCCCCCCHHH
IRGFARGRTDIHFPRPRAVTITQPTETGQVYSLEEIRAVAATCRELGLKLHMDGARFANA
HHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHCCCEEEECHHHHHHH
VESLGCTPADMTWRSGVDVLSFGGTKNGMAIGEAVIFFNRSLAEGFDYRCKQAGQLASKM
HHHHCCCCCCCCHHCCCCEEEECCCCCCCHHHHEEEEECCHHHHCCCHHHHHHHHHHHHH
RFLSAPWAVMFETGAWRANAAHANACARHFADQVADLPGVEVQFPVEANAVFLKLPPETT
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHH
AALRARGWLFYTFIGDSARFMFAWDSERARIDALAADLRAITRTPA
HHHHHCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]