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The map label for this gene is rpe [H]

Identifier: 162148165

GI number: 162148165

Start: 2456344

End: 2457081

Strand: Reverse

Name: rpe [H]

Synonym: GDI_2382

Alternate gene names: 162148165

Gene position: 2457081-2456344 (Counterclockwise)

Preceding gene: 162148166

Following gene: 162148164

Centisome position: 62.3

GC content: 67.89

Gene sequence:

>738_bases
ATGCGACGGAGGCACGCAACGGCTTGCACGCGGCATGTGATTTACTGTTACACTGTCCCCATGCCTGCTCACTTCCCCCC
CCTCGTCGCGCCCAGCGTCCTGTCGGCTGATTTCTCCCGCATGGCGGACGAAGTCAGCGCCGTCGAGCGCGCGGGTGCCG
ACTGGCTGCACCTGGACGTGATGGACGGCCATTTCGTGCCGAACCTGTCCTTCGGCGCGCAGCTCATCAAGGCGTTGCGC
CCGCAATCCAGCCTGGTGTTCGACGTCCACCTGATGATGGCGCCGGTCGATCCGTACCTGGAAATGTTTGCCCAGGCGGG
CGCCGACCATATCCATGTCCATATCGAGGCCGGCCCCCATACCCATCGGACCCTGCAGCATATCCGCTCGCTGGGCGTGA
AGCCGGGGGTCGCCATCTGCCCCGCCACCCCGCCCGAGGCGGTGGCCGAGGTGCTGGACCTGGTGGACGTGATCCTGGTC
ATGACGGTCAACCCCGGTTTCGGGGGCCAGAAATTCCTGACCAGCCAGTTGGGCAAGATCCGCACGCTGCGCCGCCTGGC
GGACGCGACGGGCCGCGACATCCGCATCGGCGTCGATGGCGGCGTGGATGTGGAAACCGCGGCGCTGGCCACAGAGGCGG
GGGCCGACATGCTGGTGGCCGGAACCTCGGTCTACGGCCAGCCGGATTATGGCCGGGCGATTTCCGCCCTGCGCGAGGCC
GGCCGCCGGCCCGCATGA

Upstream 100 bases:

>100_bases
CGGTAGGCCGGGCCAGGGCAGGCACGGGACCCAGGGCCGGCATGGAACCCAGGGCAGCAGGGGACATGGACGCGGGCAAG
CACGATCGTGATCCGCCGGG

Downstream 100 bases:

>100_bases
CGAAAGCCGGACTGACGGACGCACGGCGCGCGTCCGGATATCGTGGGATGAGAGGGGCCTGATGGTCCTGCGACGCTGGA
GCCAGGACGCGCGTCTTTCA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRRRHATACTRHVIYCYTVPMPAHFPPLVAPSVLSADFSRMADEVSAVERAGADWLHLDVMDGHFVPNLSFGAQLIKALR
PQSSLVFDVHLMMAPVDPYLEMFAQAGADHIHVHIEAGPHTHRTLQHIRSLGVKPGVAICPATPPEAVAEVLDLVDVILV
MTVNPGFGGQKFLTSQLGKIRTLRRLADATGRDIRIGVDGGVDVETAALATEAGADMLVAGTSVYGQPDYGRAISALREA
GRRPA

Sequences:

>Translated_245_residues
MRRRHATACTRHVIYCYTVPMPAHFPPLVAPSVLSADFSRMADEVSAVERAGADWLHLDVMDGHFVPNLSFGAQLIKALR
PQSSLVFDVHLMMAPVDPYLEMFAQAGADHIHVHIEAGPHTHRTLQHIRSLGVKPGVAICPATPPEAVAEVLDLVDVILV
MTVNPGFGGQKFLTSQLGKIRTLRRLADATGRDIRIGVDGGVDVETAALATEAGADMLVAGTSVYGQPDYGRAISALREA
GRRPA
>Mature_245_residues
MRRRHATACTRHVIYCYTVPMPAHFPPLVAPSVLSADFSRMADEVSAVERAGADWLHLDVMDGHFVPNLSFGAQLIKALR
PQSSLVFDVHLMMAPVDPYLEMFAQAGADHIHVHIEAGPHTHRTLQHIRSLGVKPGVAICPATPPEAVAEVLDLVDVILV
MTVNPGFGGQKFLTSQLGKIRTLRRLADATGRDIRIGVDGGVDVETAALATEAGADMLVAGTSVYGQPDYGRAISALREA
GRRPA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=213, Percent_Identity=38.9671361502347, Blast_Score=151, Evalue=4e-37,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=37.0892018779343, Blast_Score=141, Evalue=5e-34,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=32.5443786982249, Blast_Score=84, Evalue=8e-17,
Organism=Escherichia coli, GI1789788, Length=212, Percent_Identity=49.0566037735849, Blast_Score=203, Evalue=8e-54,
Organism=Escherichia coli, GI1790523, Length=196, Percent_Identity=34.1836734693878, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790754, Length=203, Percent_Identity=29.5566502463054, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=219, Percent_Identity=40.1826484018265, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6322341, Length=226, Percent_Identity=39.8230088495575, Blast_Score=165, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=40.0943396226415, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 26338; Mature: 26338

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRHATACTRHVIYCYTVPMPAHFPPLVAPSVLSADFSRMADEVSAVERAGADWLHLDV
CCCCHHHHHHCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
MDGHFVPNLSFGAQLIKALRPQSSLVFDVHLMMAPVDPYLEMFAQAGADHIHVHIEAGPH
ECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCC
THRTLQHIRSLGVKPGVAICPATPPEAVAEVLDLVDVILVMTVNPGFGGQKFLTSQLGKI
HHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
RTLRRLADATGRDIRIGVDGGVDVETAALATEAGADMLVAGTSVYGQPDYGRAISALREA
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHC
GRRPA
CCCCC
>Mature Secondary Structure
MRRRHATACTRHVIYCYTVPMPAHFPPLVAPSVLSADFSRMADEVSAVERAGADWLHLDV
CCCCHHHHHHCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
MDGHFVPNLSFGAQLIKALRPQSSLVFDVHLMMAPVDPYLEMFAQAGADHIHVHIEAGPH
ECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCC
THRTLQHIRSLGVKPGVAICPATPPEAVAEVLDLVDVILVMTVNPGFGGQKFLTSQLGKI
HHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHH
RTLRRLADATGRDIRIGVDGGVDVETAALATEAGADMLVAGTSVYGQPDYGRAISALREA
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHC
GRRPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]