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The map label for this gene is yleA [C]

Identifier: 162148088

GI number: 162148088

Start: 2368252

End: 2369514

Strand: Reverse

Name: yleA [C]

Synonym: GDI_2305

Alternate gene names: 162148088

Gene position: 2369514-2368252 (Counterclockwise)

Preceding gene: 162148089

Following gene: 162148087

Centisome position: 60.08

GC content: 71.58

Gene sequence:

>1263_bases
ATGACCGCCAAGCCGGAGATCCTGACCTTCGGGTGCCGCCTGAACACCTATGAGAGCGAGGTGATGCGCGGTCACGCGGC
GGCGCTGGACGACGTGATCATCGTCAATACCTGCGCGGTGACGGCCGAGGCCGAGCGGCAGGCCCGCCAGGCGATCCGGC
GCGCCCATCGCGACCGGCCCGGCGCGCGGATCGTCGTGACCGGCTGCGCCGCGCAGATCGACCCGGACCGCTGGTCGGCG
CTGCCGGGCGTCACCCGCGTCCTGGGCAATCGCGAGAAGCTGGAGGCCGCAAGCTGGACCCCCGCCGCGATGCAGGACGG
CCACGCCGTATCCGACATCATGGCGGCGACCGAGACGGTGCCGCATCTGGTGACGGAATTCGCCGGCCGTACCCGCGCGT
TCGTCGAGGTGCAGCAGGGCTGCGACCATCGCTGCACCTTCTGCATCATCCCGTTCGGCCGGGGGCCGTCGCGCTCGGTT
CCGGTCGGGGCAGTGGTGGAACAGGTCCGTGCCCTGGTCGCCTCGGGCTATCGCGAGATCGTGCTGACCGGGGTCGACAT
CACCTCGTGGGGCGGCGACCTGCCGGGCCGTCCGGCGCTGGGGCAGCTCTGCCGGCGGGTGCTGGCGCTGGTACCGGAAC
TGGAGCGGCTGCGCCTGTCCTCGGTCGATCCGGTGGAAATCGACGACGATCTGTGGCGCCTGCTGGCGCAGGAGGGGCGA
TTCATGCCCTATCTGCACCTGTCGCTGCAGGCCGGGTCGGACATGGTGCTGAAGCGGATGAAGCGCCGGCACCTGGTCGA
GGACGTGGCGCGCGTGCTGGACCGCGCCCGTGCCTGCCGCCCCGACCTGGGGATCGGCGCCGACGTCATCGCGGGCTTCC
CGACCGAGACCGATGCCCTGTTCGCCGAAACGCTGGATTTCGTGCGTGCGCAGCGCCTGCCGTACCTGCACGTCTTTCCC
TATAGTGAGCGGCCGGGCACCCCGGCGGCGCGGATGCCCGCCGTGCCCGTGGCCGTGCGCAAGGAGCGCGCGGCCCAACT
GCGCGCGGCGGGGCAGGCGGCGGCGCGGGACTATCACGCCAGCCTGCTGGGGCGGACGCTGAACGTGCTGCTGGAAACCG
CGACCACTGGCCATTCCGAGGAATTCGCCCCCGTCCGGCTGGCCCCGGACAGGCTGGACGGTACTGCGGCCGAGGCGGGG
CGGATCGTGACCGTCCGGGCGACGGCGATTGACGAAAACGGACTGGTGGCGGAAACCCTCTGA

Upstream 100 bases:

>100_bases
GGCGCGCGCAGGATGACCCAGGGGAAGGGGGGCATGTGCTGATGACCGGCCCCGCCACCGTCAGCTTCGTCGGCACGTTC
GATCCCGAAGGCTATCCGTC

Downstream 100 bases:

>100_bases
CATGGCACTTGGTTTTTTCTCCCGCCTCAAGGCGGGGCTGTCCCGTTCGACCCAGAAGCTGGGCGGTGGCATCGCCGCGG
TCTTCACGCGCCGCAAGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTAKPEILTFGCRLNTYESEVMRGHAAALDDVIIVNTCAVTAEAERQARQAIRRAHRDRPGARIVVTGCAAQIDPDRWSA
LPGVTRVLGNREKLEAASWTPAAMQDGHAVSDIMAATETVPHLVTEFAGRTRAFVEVQQGCDHRCTFCIIPFGRGPSRSV
PVGAVVEQVRALVASGYREIVLTGVDITSWGGDLPGRPALGQLCRRVLALVPELERLRLSSVDPVEIDDDLWRLLAQEGR
FMPYLHLSLQAGSDMVLKRMKRRHLVEDVARVLDRARACRPDLGIGADVIAGFPTETDALFAETLDFVRAQRLPYLHVFP
YSERPGTPAARMPAVPVAVRKERAAQLRAAGQAAARDYHASLLGRTLNVLLETATTGHSEEFAPVRLAPDRLDGTAAEAG
RIVTVRATAIDENGLVAETL

Sequences:

>Translated_420_residues
MTAKPEILTFGCRLNTYESEVMRGHAAALDDVIIVNTCAVTAEAERQARQAIRRAHRDRPGARIVVTGCAAQIDPDRWSA
LPGVTRVLGNREKLEAASWTPAAMQDGHAVSDIMAATETVPHLVTEFAGRTRAFVEVQQGCDHRCTFCIIPFGRGPSRSV
PVGAVVEQVRALVASGYREIVLTGVDITSWGGDLPGRPALGQLCRRVLALVPELERLRLSSVDPVEIDDDLWRLLAQEGR
FMPYLHLSLQAGSDMVLKRMKRRHLVEDVARVLDRARACRPDLGIGADVIAGFPTETDALFAETLDFVRAQRLPYLHVFP
YSERPGTPAARMPAVPVAVRKERAAQLRAAGQAAARDYHASLLGRTLNVLLETATTGHSEEFAPVRLAPDRLDGTAAEAG
RIVTVRATAIDENGLVAETL
>Mature_419_residues
TAKPEILTFGCRLNTYESEVMRGHAAALDDVIIVNTCAVTAEAERQARQAIRRAHRDRPGARIVVTGCAAQIDPDRWSAL
PGVTRVLGNREKLEAASWTPAAMQDGHAVSDIMAATETVPHLVTEFAGRTRAFVEVQQGCDHRCTFCIIPFGRGPSRSVP
VGAVVEQVRALVASGYREIVLTGVDITSWGGDLPGRPALGQLCRRVLALVPELERLRLSSVDPVEIDDDLWRLLAQEGRF
MPYLHLSLQAGSDMVLKRMKRRHLVEDVARVLDRARACRPDLGIGADVIAGFPTETDALFAETLDFVRAQRLPYLHVFPY
SERPGTPAARMPAVPVAVRKERAAQLRAAGQAAARDYHASLLGRTLNVLLETATTGHSEEFAPVRLAPDRLDGTAAEAGR
IVTVRATAIDENGLVAETL

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=366, Percent_Identity=29.7814207650273, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI28872784, Length=422, Percent_Identity=26.303317535545, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI28872782, Length=422, Percent_Identity=26.303317535545, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI1786882, Length=436, Percent_Identity=28.2110091743119, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1787057, Length=443, Percent_Identity=29.5711060948081, Blast_Score=151, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17553146, Length=431, Percent_Identity=26.9141531322506, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71996771, Length=293, Percent_Identity=29.0102389078498, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19922432, Length=448, Percent_Identity=29.9107142857143, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356207, Length=426, Percent_Identity=26.7605633802817, Blast_Score=147, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 45720; Mature: 45589

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKPEILTFGCRLNTYESEVMRGHAAALDDVIIVNTCAVTAEAERQARQAIRRAHRDRP
CCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHCCCC
GARIVVTGCAAQIDPDRWSALPGVTRVLGNREKLEAASWTPAAMQDGHAVSDIMAATETV
CCEEEEEECCCCCCHHHHHHCCHHHHHHCCHHHHCCCCCCCHHHCCCCHHHHHHHHHHHH
PHLVTEFAGRTRAFVEVQQGCDHRCTFCIIPFGRGPSRSVPVGAVVEQVRALVASGYREI
HHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VLTGVDITSWGGDLPGRPALGQLCRRVLALVPELERLRLSSVDPVEIDDDLWRLLAQEGR
EEECCEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHCCC
FMPYLHLSLQAGSDMVLKRMKRRHLVEDVARVLDRARACRPDLGIGADVIAGFPTETDAL
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHH
FAETLDFVRAQRLPYLHVFPYSERPGTPAARMPAVPVAVRKERAAQLRAAGQAAARDYHA
HHHHHHHHHHHCCCEEEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLLGRTLNVLLETATTGHSEEFAPVRLAPDRLDGTAAEAGRIVTVRATAIDENGLVAETL
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHCCCCEEEEEEEEECCCCCEECCC
>Mature Secondary Structure 
TAKPEILTFGCRLNTYESEVMRGHAAALDDVIIVNTCAVTAEAERQARQAIRRAHRDRP
CCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEEECHHHHHHHHHHHHHHHCCCC
GARIVVTGCAAQIDPDRWSALPGVTRVLGNREKLEAASWTPAAMQDGHAVSDIMAATETV
CCEEEEEECCCCCCHHHHHHCCHHHHHHCCHHHHCCCCCCCHHHCCCCHHHHHHHHHHHH
PHLVTEFAGRTRAFVEVQQGCDHRCTFCIIPFGRGPSRSVPVGAVVEQVRALVASGYREI
HHHHHHHCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEE
VLTGVDITSWGGDLPGRPALGQLCRRVLALVPELERLRLSSVDPVEIDDDLWRLLAQEGR
EEECCEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHCCC
FMPYLHLSLQAGSDMVLKRMKRRHLVEDVARVLDRARACRPDLGIGADVIAGFPTETDAL
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCHHHH
FAETLDFVRAQRLPYLHVFPYSERPGTPAARMPAVPVAVRKERAAQLRAAGQAAARDYHA
HHHHHHHHHHHCCCEEEEECCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLLGRTLNVLLETATTGHSEEFAPVRLAPDRLDGTAAEAGRIVTVRATAIDENGLVAETL
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCHHCCCCEEEEEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]