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The map label for this gene is ntrY [C]

Identifier: 162148048

GI number: 162148048

Start: 2321790

End: 2324006

Strand: Reverse

Name: ntrY [C]

Synonym: GDI_2264

Alternate gene names: 162148048

Gene position: 2324006-2321790 (Counterclockwise)

Preceding gene: 162148049

Following gene: 162148047

Centisome position: 58.92

GC content: 66.44

Gene sequence:

>2217_bases
ATGCGCGGCCTGTTCGGGCTGCTGGCGCGGCGCGACGTGACCATCGCCCTGGTCGCGCTGGCGCTGTGTTTCGGGGTCGC
GACCTTCGTGGTGCTGTCCGGCGGCCTGTCGGTGACGCATTACCCCCGCATCCAGGCGCTGATCTTCGTACTGAATTTCC
TGGTCCTGCTGCTGCTGGCCCTGGCGCTGTCGGAACGGCTGGGTCGCGTCCTGGCCGAACGGCGGCGCGGCCTGGCCGGG
GCGCGGCTGCATGTGCGCCTGGTCACGCTGTTCGGCATCGTGGCGGTGGCGCCCACCATCGTCGTCGGCTGCTTCGCCAC
GGTGTTCTTCCATTACGGCATCCAGATCTGGTTCAGCGACCGGGTGAACACCGCGCTGAACGAGGCGCTGCAGGCCTCGC
ACGGCTATCTGCAGGAACATAACGCCAATATCCGGACCGAGGCCTTCTCGCTGGCCAACTACCTGGCCGGCGCGGCCAAC
GGCCTGGAAGGGTCGGGGTCGGACCTGATGCACGACCCCGAGGCCCTGGATCAGATCCTCGATTCGCAGGCCACCCTGCG
CGGCCTGAACGAGGCGGTGATCTACGACCCGCTGACCAACCACATCGTGGCCTCGGGCGGGCTGATGAGCCACCCGGGCG
ACATGCAGGCCCTGCCGCCGCCCTCGGCCACCATGATGGCCCGCACCAACGAGATCGCCATTCTCGATTCGCCCGACGAG
AAGACGGTCCGGGCGGTCATCTCGCTGGGCGACACGCCGCCGCTGATGCTGGTGATCACCCGCCCCGTCGATCCCGAAAT
CCTCGACCACATGCACAAGACCGAAAATGTGGTGGCCGATTACCAGCGGCTGAACCGGAACCGCTCGAAAATCCAGTTCA
CCTTCGTGCTGATTTTCGCGCTGGTGGGGCTTCTGGTGCTGTTCGCGGCGATCCTGATCGGCCTGGTGCTGGCCAACCAG
ATCGTCCGGCCGCTGGGCCTGCTGATCCTGGCATCCGGACGGATCAGCGACGGCGACCTGAAGGTGCGCGTCCCCGAGGG
CGAGCGCGACGATGAGCTGTCCAGCCTGTCGCGTGCCTTCAACCGCATGACCGACCAGCTTTCCAGCCAGCGTTCGGAAC
TGATGATCGCCTACGACCAGATCGACGAACGCCGCCGCTTTACCGAAGCCGTGCTGTCGGGCGTGTCGGCGGGCGTGATC
GGCCTGGACGCGCAGCAGGTGATCGAACTGCCCAACCGTGCGGCGGCCACCCTGCTTCAGCAGGATCTGGCGGCGGCCAT
CGGCCGGCGCCTGGTCGACGTGGTGCCGGAATTCCATCCGATGCTGGACGAGGTGGCGCGGGCTTCCGACCGGGTCTGGA
CCGGCGAGGTCCAGGTGGGCAGCGGCGCGCGGGCCTGCACGCTGCTGGTCCGGATCGGGGCCGAGACCCGTGGCGCCAAG
GCCGAGGGCTATGTCGTGACGTTCGACGACATAACGGCATTGCAGGCAGCGCAACGCAAGGCCGCCTGGGCCGACGTCGC
CCGACGCATCGCGCACGAGATCAAGAATCCCCTGACGCCGATCCAGCTCGCGGCCGAACGGCTGAAGCGGCGCTTCCTGC
GCGAGATCACGTCGGATCCCGAAACGTTCAGCCAGTGCGCGGACACGATCGTGCGCCATGTCGGCGATATCGGGCGCATG
GTGGACGAATTTTCCGCCTTCGCGCGGATGCCGCAGCCGATCATCCGCCCCGAGGACCTGTCGCGCATCGTGCGCGAGGC
CCTGGTCCTGCAACGCGCCGCCCACCCCGAGATCCGCTACGAAACCGACCTGCCCGAACACGGGCCGGTGGTGTCATGCG
ACCGGCGGCTGATGGTCCAGGCGCTGACCAATTTGCTGCAGAATGCGGCCGACGCCATTGCAATGGTACCAAAAGATGGG
AATGCTGCATGCAGCCCGGCCGGTCCGGCCGGCATCGTCGGGATTGTCTTGCACATCGAAGGTTCGGAGGCCCACCTCAC
GGTGGCCGACGACGGGATCGGCCTGCCGGAAGAAGACAGGCAGCGATTGACCGAACCCTATGTGACCCACAAGCCGAAAG
GAACCGGCCTGGGTCTGGCGATCGTCAAGAAAATCCTGGAAGATCATGGTGGTAGCATCCGTCTGGAGGACCGGCCAGAC
GCAAGGGGAGCGGTTTCGATCTTGATACTGCCTGTAAAGGACGACCATGGGGCATGA

Upstream 100 bases:

>100_bases
GAAATCCCTGTCGTTCGCGGCGCGAACTGACCGTGAAGCGGGAGATCGTCCATTGACCGAACCCAGGGCATCCCGCGCCC
GGATTCCGGCGCCGCCGCTG

Downstream 100 bases:

>100_bases
AATCCTGATCGTCGATGATGAGCCGGACATCCGGCTGCTTGTCGAGGGCATTCTTCGGGACGAAGGCTACGAGACCCGCC
TGGCAGGGGATTCGGATTCG

Product: histidine kinase, nitrogen regulation protein ntrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 738; Mature: 738

Protein sequence:

>738_residues
MRGLFGLLARRDVTIALVALALCFGVATFVVLSGGLSVTHYPRIQALIFVLNFLVLLLLALALSERLGRVLAERRRGLAG
ARLHVRLVTLFGIVAVAPTIVVGCFATVFFHYGIQIWFSDRVNTALNEALQASHGYLQEHNANIRTEAFSLANYLAGAAN
GLEGSGSDLMHDPEALDQILDSQATLRGLNEAVIYDPLTNHIVASGGLMSHPGDMQALPPPSATMMARTNEIAILDSPDE
KTVRAVISLGDTPPLMLVITRPVDPEILDHMHKTENVVADYQRLNRNRSKIQFTFVLIFALVGLLVLFAAILIGLVLANQ
IVRPLGLLILASGRISDGDLKVRVPEGERDDELSSLSRAFNRMTDQLSSQRSELMIAYDQIDERRRFTEAVLSGVSAGVI
GLDAQQVIELPNRAAATLLQQDLAAAIGRRLVDVVPEFHPMLDEVARASDRVWTGEVQVGSGARACTLLVRIGAETRGAK
AEGYVVTFDDITALQAAQRKAAWADVARRIAHEIKNPLTPIQLAAERLKRRFLREITSDPETFSQCADTIVRHVGDIGRM
VDEFSAFARMPQPIIRPEDLSRIVREALVLQRAAHPEIRYETDLPEHGPVVSCDRRLMVQALTNLLQNAADAIAMVPKDG
NAACSPAGPAGIVGIVLHIEGSEAHLTVADDGIGLPEEDRQRLTEPYVTHKPKGTGLGLAIVKKILEDHGGSIRLEDRPD
ARGAVSILILPVKDDHGA

Sequences:

>Translated_738_residues
MRGLFGLLARRDVTIALVALALCFGVATFVVLSGGLSVTHYPRIQALIFVLNFLVLLLLALALSERLGRVLAERRRGLAG
ARLHVRLVTLFGIVAVAPTIVVGCFATVFFHYGIQIWFSDRVNTALNEALQASHGYLQEHNANIRTEAFSLANYLAGAAN
GLEGSGSDLMHDPEALDQILDSQATLRGLNEAVIYDPLTNHIVASGGLMSHPGDMQALPPPSATMMARTNEIAILDSPDE
KTVRAVISLGDTPPLMLVITRPVDPEILDHMHKTENVVADYQRLNRNRSKIQFTFVLIFALVGLLVLFAAILIGLVLANQ
IVRPLGLLILASGRISDGDLKVRVPEGERDDELSSLSRAFNRMTDQLSSQRSELMIAYDQIDERRRFTEAVLSGVSAGVI
GLDAQQVIELPNRAAATLLQQDLAAAIGRRLVDVVPEFHPMLDEVARASDRVWTGEVQVGSGARACTLLVRIGAETRGAK
AEGYVVTFDDITALQAAQRKAAWADVARRIAHEIKNPLTPIQLAAERLKRRFLREITSDPETFSQCADTIVRHVGDIGRM
VDEFSAFARMPQPIIRPEDLSRIVREALVLQRAAHPEIRYETDLPEHGPVVSCDRRLMVQALTNLLQNAADAIAMVPKDG
NAACSPAGPAGIVGIVLHIEGSEAHLTVADDGIGLPEEDRQRLTEPYVTHKPKGTGLGLAIVKKILEDHGGSIRLEDRPD
ARGAVSILILPVKDDHGA
>Mature_738_residues
MRGLFGLLARRDVTIALVALALCFGVATFVVLSGGLSVTHYPRIQALIFVLNFLVLLLLALALSERLGRVLAERRRGLAG
ARLHVRLVTLFGIVAVAPTIVVGCFATVFFHYGIQIWFSDRVNTALNEALQASHGYLQEHNANIRTEAFSLANYLAGAAN
GLEGSGSDLMHDPEALDQILDSQATLRGLNEAVIYDPLTNHIVASGGLMSHPGDMQALPPPSATMMARTNEIAILDSPDE
KTVRAVISLGDTPPLMLVITRPVDPEILDHMHKTENVVADYQRLNRNRSKIQFTFVLIFALVGLLVLFAAILIGLVLANQ
IVRPLGLLILASGRISDGDLKVRVPEGERDDELSSLSRAFNRMTDQLSSQRSELMIAYDQIDERRRFTEAVLSGVSAGVI
GLDAQQVIELPNRAAATLLQQDLAAAIGRRLVDVVPEFHPMLDEVARASDRVWTGEVQVGSGARACTLLVRIGAETRGAK
AEGYVVTFDDITALQAAQRKAAWADVARRIAHEIKNPLTPIQLAAERLKRRFLREITSDPETFSQCADTIVRHVGDIGRM
VDEFSAFARMPQPIIRPEDLSRIVREALVLQRAAHPEIRYETDLPEHGPVVSCDRRLMVQALTNLLQNAADAIAMVPKDG
NAACSPAGPAGIVGIVLHIEGSEAHLTVADDGIGLPEEDRQRLTEPYVTHKPKGTGLGLAIVKKILEDHGGSIRLEDRPD
ARGAVSILILPVKDDHGA

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=401, Percent_Identity=26.1845386533666, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=27.6, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789808, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=259, Percent_Identity=27.4131274131274, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=272, Percent_Identity=25.7352941176471, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790567, Length=350, Percent_Identity=24.8571428571429, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80184; Mature: 80184

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLFGLLARRDVTIALVALALCFGVATFVVLSGGLSVTHYPRIQALIFVLNFLVLLLLA
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LALSERLGRVLAERRRGLAGARLHVRLVTLFGIVAVAPTIVVGCFATVFFHYGIQIWFSD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
RVNTALNEALQASHGYLQEHNANIRTEAFSLANYLAGAANGLEGSGSDLMHDPEALDQIL
HHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
DSQATLRGLNEAVIYDPLTNHIVASGGLMSHPGDMQALPPPSATMMARTNEIAILDSPDE
CCHHHHHCCCHHEEECCHHHHHEECCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCH
KTVRAVISLGDTPPLMLVITRPVDPEILDHMHKTENVVADYQRLNRNRSKIQFTFVLIFA
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVGLLVLFAAILIGLVLANQIVRPLGLLILASGRISDGDLKVRVPEGERDDELSSLSRAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
NRMTDQLSSQRSELMIAYDQIDERRRFTEAVLSGVSAGVIGLDAQQVIELPNRAAATLLQ
HHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHCCCHHHHHHHH
QDLAAAIGRRLVDVVPEFHPMLDEVARASDRVWTGEVQVGSGARACTLLVRIGAETRGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEECCCCHHHHHHHHCCCCCCCCC
AEGYVVTFDDITALQAAQRKAAWADVARRIAHEIKNPLTPIQLAAERLKRRFLREITSDP
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
ETFSQCADTIVRHVGDIGRMVDEFSAFARMPQPIIRPEDLSRIVREALVLQRAAHPEIRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
ETDLPEHGPVVSCDRRLMVQALTNLLQNAADAIAMVPKDGNAACSPAGPAGIVGIVLHIE
ECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEEEEE
GSEAHLTVADDGIGLPEEDRQRLTEPYVTHKPKGTGLGLAIVKKILEDHGGSIRLEDRPD
CCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCC
ARGAVSILILPVKDDHGA
CCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MRGLFGLLARRDVTIALVALALCFGVATFVVLSGGLSVTHYPRIQALIFVLNFLVLLLLA
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LALSERLGRVLAERRRGLAGARLHVRLVTLFGIVAVAPTIVVGCFATVFFHYGIQIWFSD
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
RVNTALNEALQASHGYLQEHNANIRTEAFSLANYLAGAANGLEGSGSDLMHDPEALDQIL
HHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
DSQATLRGLNEAVIYDPLTNHIVASGGLMSHPGDMQALPPPSATMMARTNEIAILDSPDE
CCHHHHHCCCHHEEECCHHHHHEECCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCH
KTVRAVISLGDTPPLMLVITRPVDPEILDHMHKTENVVADYQRLNRNRSKIQFTFVLIFA
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LVGLLVLFAAILIGLVLANQIVRPLGLLILASGRISDGDLKVRVPEGERDDELSSLSRAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
NRMTDQLSSQRSELMIAYDQIDERRRFTEAVLSGVSAGVIGLDAQQVIELPNRAAATLLQ
HHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHCCCHHHHHHHH
QDLAAAIGRRLVDVVPEFHPMLDEVARASDRVWTGEVQVGSGARACTLLVRIGAETRGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEEECCCCHHHHHHHHCCCCCCCCC
AEGYVVTFDDITALQAAQRKAAWADVARRIAHEIKNPLTPIQLAAERLKRRFLREITSDP
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCH
ETFSQCADTIVRHVGDIGRMVDEFSAFARMPQPIIRPEDLSRIVREALVLQRAAHPEIRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEE
ETDLPEHGPVVSCDRRLMVQALTNLLQNAADAIAMVPKDGNAACSPAGPAGIVGIVLHIE
ECCCCCCCCEECHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEEEEE
GSEAHLTVADDGIGLPEEDRQRLTEPYVTHKPKGTGLGLAIVKKILEDHGGSIRLEDRPD
CCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCC
ARGAVSILILPVKDDHGA
CCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7553451 [H]