Click here to switch to the map view.

The map label for this gene is accA

Identifier: 162147965

GI number: 162147965

Start: 2231481

End: 2232437

Strand: Reverse

Name: accA

Synonym: GDI_2181

Alternate gene names: 162147965

Gene position: 2232437-2231481 (Counterclockwise)

Preceding gene: 162147966

Following gene: 162147963

Centisome position: 56.6

GC content: 67.19

Gene sequence:

>957_bases
ATGCGCCAGTTTCTAGATTTCGAAAAGTCGGTCGCCGAGCTTGAGAACAAGATCGACGAGCTTCGCAAGATGTCCGAGCC
CGATGGCATCAATCTTGCCGAAGAAATCGCCCGCCTGACGGACAAGTCCGAAAAGCAGCTTCGCGCGGCCTATGCCAAGC
TGAGCCCGTGGCAGAAGGTCCAGGTCGCCCGCCATGCCCAGCGTCCGCACGCCGCGGACTACATCGGCACGCTGATCCAG
GATTTCACGCCCCTGGCCGGCGACCGGCTGTTCGGCGAGGACAAGGCGGTGATCGGCGGCATAGGCCGGTTCCAGAATCA
GCCGGTGGTGGTGATCGGGACCGAGCGCGGTTCGGAACTGGAAAGCCGGCTGGCGCATAATTTCGGCATGGCGCGGCCCG
AGGGCTATCGCAAGGCGCAGCGCCTGATGGAACTGGCGGGCCGCTTCGGCATGCCGATCCTGACCTTCATCGACACGTCG
GGCGCGTGGCCCGGCATCGATGCCGAGGCACGCGGCCAGGCCGAGGCGATCGCGCGGTCCATCGACACCTGCCTGTCGGC
GCCGGTGCCGGTGATCGCCACCGTGATCGGCGAGGGCGGGTCCGGCGGCGCCATCGCCCTGGGCGCGGGCGACCGGGTGA
TGATGCTGGAACACGCGATCTATTCGGTGATCTCGCCCGAAGCCTGCGCGTCGATCCTGTGGCGCGACCCCAAGCAGGCG
ACCAGCGCGGCCGAGGCGCTGAAGCTGACGGCGCAGGACCTGCTGCAACTGAAGCTGATCGACCGGATCATCCCCGAGCC
GGTGGGGGGCGCCCAGCGCGACCCAGAAAGCACCATTCGCTCGGTTGGCGATTCGATCGCGGCCGAACTGCCCGACCTGC
TGTCGCTCAGCGCCCCCATGCTGGTCGCGCAGCGGCGGGAAAAATTCCTCGCCATGGGCCGCGACAGCCTGAGCTGA

Upstream 100 bases:

>100_bases
GCGCGTGGCGGGGACGGAGAAACCCGCTGAAAACCGTCCCGGTTGTGGTTTCGCTGCGGAATAGACTTGGCAGGATTCGT
GGCTGTGCTATCCGCACCGC

Downstream 100 bases:

>100_bases
ACGGGCCCTTTACGGCGGTTCGCCCTCCGCTGGGGTGAAGCCCAGCCGTTCGATCAGTTCGCGCACGCGGTCCGCCGCGT
GGCAGACGGCGGCGGCGTCC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRQFLDFEKSVAELENKIDELRKMSEPDGINLAEEIARLTDKSEKQLRAAYAKLSPWQKVQVARHAQRPHAADYIGTLIQ
DFTPLAGDRLFGEDKAVIGGIGRFQNQPVVVIGTERGSELESRLAHNFGMARPEGYRKAQRLMELAGRFGMPILTFIDTS
GAWPGIDAEARGQAEAIARSIDTCLSAPVPVIATVIGEGGSGGAIALGAGDRVMMLEHAIYSVISPEACASILWRDPKQA
TSAAEALKLTAQDLLQLKLIDRIIPEPVGGAQRDPESTIRSVGDSIAAELPDLLSLSAPMLVAQRREKFLAMGRDSLS

Sequences:

>Translated_318_residues
MRQFLDFEKSVAELENKIDELRKMSEPDGINLAEEIARLTDKSEKQLRAAYAKLSPWQKVQVARHAQRPHAADYIGTLIQ
DFTPLAGDRLFGEDKAVIGGIGRFQNQPVVVIGTERGSELESRLAHNFGMARPEGYRKAQRLMELAGRFGMPILTFIDTS
GAWPGIDAEARGQAEAIARSIDTCLSAPVPVIATVIGEGGSGGAIALGAGDRVMMLEHAIYSVISPEACASILWRDPKQA
TSAAEALKLTAQDLLQLKLIDRIIPEPVGGAQRDPESTIRSVGDSIAAELPDLLSLSAPMLVAQRREKFLAMGRDSLS
>Mature_318_residues
MRQFLDFEKSVAELENKIDELRKMSEPDGINLAEEIARLTDKSEKQLRAAYAKLSPWQKVQVARHAQRPHAADYIGTLIQ
DFTPLAGDRLFGEDKAVIGGIGRFQNQPVVVIGTERGSELESRLAHNFGMARPEGYRKAQRLMELAGRFGMPILTFIDTS
GAWPGIDAEARGQAEAIARSIDTCLSAPVPVIATVIGEGGSGGAIALGAGDRVMMLEHAIYSVISPEACASILWRDPKQA
TSAAEALKLTAQDLLQLKLIDRIIPEPVGGAQRDPESTIRSVGDSIAAELPDLLSLSAPMLVAQRREKFLAMGRDSLS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=51.5923566878981, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_GLUDA (A9HL57)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001602426.1
- RefSeq:   YP_002274811.1
- ProteinModelPortal:   A9HL57
- SMR:   A9HL57
- GeneID:   5792540
- GeneID:   6973794
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_0400
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34439; Mature: 34439

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQFLDFEKSVAELENKIDELRKMSEPDGINLAEEIARLTDKSEKQLRAAYAKLSPWQKV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCCHHHH
QVARHAQRPHAADYIGTLIQDFTPLAGDRLFGEDKAVIGGIGRFQNQPVVVIGTERGSEL
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHH
ESRLAHNFGMARPEGYRKAQRLMELAGRFGMPILTFIDTSGAWPGIDAEARGQAEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
IDTCLSAPVPVIATVIGEGGSGGAIALGAGDRVMMLEHAIYSVISPEACASILWRDPKQA
HHHHHCCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHCCHHHH
TSAAEALKLTAQDLLQLKLIDRIIPEPVGGAQRDPESTIRSVGDSIAAELPDLLSLSAPM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
LVAQRREKFLAMGRDSLS
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRQFLDFEKSVAELENKIDELRKMSEPDGINLAEEIARLTDKSEKQLRAAYAKLSPWQKV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHCCCHHHH
QVARHAQRPHAADYIGTLIQDFTPLAGDRLFGEDKAVIGGIGRFQNQPVVVIGTERGSEL
HHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCHHH
ESRLAHNFGMARPEGYRKAQRLMELAGRFGMPILTFIDTSGAWPGIDAEARGQAEAIARS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
IDTCLSAPVPVIATVIGEGGSGGAIALGAGDRVMMLEHAIYSVISPEACASILWRDPKQA
HHHHHCCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHCCHHHH
TSAAEALKLTAQDLLQLKLIDRIIPEPVGGAQRDPESTIRSVGDSIAAELPDLLSLSAPM
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
LVAQRREKFLAMGRDSLS
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA