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The map label for this gene is pqqL [C]

Identifier: 162147873

GI number: 162147873

Start: 2139155

End: 2140420

Strand: Direct

Name: pqqL [C]

Synonym: GDI_2089

Alternate gene names: 162147873

Gene position: 2139155-2140420 (Clockwise)

Preceding gene: 162147872

Following gene: 162147874

Centisome position: 54.24

GC content: 66.19

Gene sequence:

>1266_bases
ATGACCGACCAGATCAACGTCACCCGCCTTCCCTCCGGCCTGACCGTCGTCACCGAACGCATGGAGCGCGTGGAAACCGT
GTCGTTCGGCGCCTATGTCGCCGCCGGCACGTGCAACGAGCATGCCGAGGAAAACGGCGTGTCGCACTTCCTGGAACACA
TGGCGTTCAAGGGAACGGACAGCCGCACCGCCGCCGGCATCGCCGAGGAAATCGAGAACGTGGGCGGCCATATCAACGCC
TACACCGCGCGCGAGCATACGGCCTATTACGTCAAGTTGCTGAAGGAGGACCTGGCACTGGGCGCCGACATCATCGGCGA
CATCCTGACCCACAGCAGCTTCGCCCCCGACGAGGTCGAGCGCGAGCGCGGCGTGATCCTGCAGGAAATCGGCCAGGCGA
ACGACACGCCCGACGACATCATCTTCGACCATTTCCAGGAAACCGCCTTCCCCGAACAGCCGATGGGCCGCCCCACCCTG
GGCACCGAACCGCTGATCCAGGACATGAGCCGCGAGACCCTGATGCGCTACATGCGCACCCATTACACCACCGCGAACAC
CGTGATCGCGGCGGCGGGCAACCTGCACCACGCCGATGTGGTGGCCCTGGCCGAACGGCATTTCCGCGACCTGCCGGCGC
TGGACAGTTCGACCGGCTTCGATTCCCGCTATCTGGGCGGCGAGTTCCGCAAGGAGAAGGAACTGGACCAGGCCCATGTG
GTGCTGGGCTTCCCGTCGGTGGGCTATGGCGACCCGGACTACTATCCGGTCCTGCTGCTCTCGACCCTGCTGGGCGGCGG
CATGTCGTCGCGCCTGTTCCAGGAAATCCGCGAGAAGCGCGGGCTGGTCTATTCGGTCTATTCCTTCAACGCTCCGTTCC
GCGATGGCGGCCTGTTCGGCATCTATGCCGGCACGGGCGAGGACCAGGCCGACGAACTGATCCCCGTCACGCTGGAGGAG
TTGCGCAAGGTGCAGGGCCATGTCGGACAGGACGAGCTGAACCGCGCCCGGGCGCAGTTGAAGTCCTCGCTGCTGATGTC
GCTGGAAAGCACCGGCAGCCGGTGCGAACAGCTTGCGCGGCAGTTGCAGGTGTTCGGCCGCCTGATCCCGACCGCCGAAA
CGGTGGAGCGGATCAACGCCGTCACCATCGCTGACGTGCGGCGGGTGGCCACGCGGCTGTTCCGGGGCAAGCCCACCCTG
GCCTCGCTGGGGCCGGTGCGCAACATTCCCGGCATCGCCGCCATTGCCGAGGCCCTGGCGGCATGA

Upstream 100 bases:

>100_bases
GACCGGGTTCGGGCGGCGGTGCTGAAGAACGCCTGAACCGCCCTTTTCCCATCTCTTCGGACGTCCGGCCCCGCCGGCCG
GACCGTCACGCAGGACCCTG

Downstream 100 bases:

>100_bases
GCACCGATCCGCTCGACCTCCTCGGCACCCTGATCGGCAAGGCCCGGGCGGCCGGTGCCGACGCGGCGGATGCCGTCTAC
ATGGCGCGGACCACGCACGG

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTDQINVTRLPSGLTVVTERMERVETVSFGAYVAAGTCNEHAEENGVSHFLEHMAFKGTDSRTAAGIAEEIENVGGHINA
YTAREHTAYYVKLLKEDLALGADIIGDILTHSSFAPDEVERERGVILQEIGQANDTPDDIIFDHFQETAFPEQPMGRPTL
GTEPLIQDMSRETLMRYMRTHYTTANTVIAAAGNLHHADVVALAERHFRDLPALDSSTGFDSRYLGGEFRKEKELDQAHV
VLGFPSVGYGDPDYYPVLLLSTLLGGGMSSRLFQEIREKRGLVYSVYSFNAPFRDGGLFGIYAGTGEDQADELIPVTLEE
LRKVQGHVGQDELNRARAQLKSSLLMSLESTGSRCEQLARQLQVFGRLIPTAETVERINAVTIADVRRVATRLFRGKPTL
ASLGPVRNIPGIAAIAEALAA

Sequences:

>Translated_421_residues
MTDQINVTRLPSGLTVVTERMERVETVSFGAYVAAGTCNEHAEENGVSHFLEHMAFKGTDSRTAAGIAEEIENVGGHINA
YTAREHTAYYVKLLKEDLALGADIIGDILTHSSFAPDEVERERGVILQEIGQANDTPDDIIFDHFQETAFPEQPMGRPTL
GTEPLIQDMSRETLMRYMRTHYTTANTVIAAAGNLHHADVVALAERHFRDLPALDSSTGFDSRYLGGEFRKEKELDQAHV
VLGFPSVGYGDPDYYPVLLLSTLLGGGMSSRLFQEIREKRGLVYSVYSFNAPFRDGGLFGIYAGTGEDQADELIPVTLEE
LRKVQGHVGQDELNRARAQLKSSLLMSLESTGSRCEQLARQLQVFGRLIPTAETVERINAVTIADVRRVATRLFRGKPTL
ASLGPVRNIPGIAAIAEALAA
>Mature_420_residues
TDQINVTRLPSGLTVVTERMERVETVSFGAYVAAGTCNEHAEENGVSHFLEHMAFKGTDSRTAAGIAEEIENVGGHINAY
TAREHTAYYVKLLKEDLALGADIIGDILTHSSFAPDEVERERGVILQEIGQANDTPDDIIFDHFQETAFPEQPMGRPTLG
TEPLIQDMSRETLMRYMRTHYTTANTVIAAAGNLHHADVVALAERHFRDLPALDSSTGFDSRYLGGEFRKEKELDQAHVV
LGFPSVGYGDPDYYPVLLLSTLLGGGMSSRLFQEIREKRGLVYSVYSFNAPFRDGGLFGIYAGTGEDQADELIPVTLEEL
RKVQGHVGQDELNRARAQLKSSLLMSLESTGSRCEQLARQLQVFGRLIPTAETVERINAVTIADVRRVATRLFRGKPTLA
SLGPVRNIPGIAAIAEALAA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=428, Percent_Identity=35.0467289719626, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI46593007, Length=422, Percent_Identity=30.5687203791469, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI24308013, Length=452, Percent_Identity=27.4336283185841, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI50592988, Length=416, Percent_Identity=24.0384615384615, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1787770, Length=204, Percent_Identity=25, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=417, Percent_Identity=34.2925659472422, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17553678, Length=410, Percent_Identity=27.0731707317073, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17510601, Length=457, Percent_Identity=24.0700218818381, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17569737, Length=381, Percent_Identity=23.0971128608924, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323192, Length=432, Percent_Identity=33.5648148148148, Blast_Score=263, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6321813, Length=430, Percent_Identity=27.4418604651163, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319426, Length=438, Percent_Identity=24.6575342465753, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357875, Length=415, Percent_Identity=34.6987951807229, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24646943, Length=415, Percent_Identity=34.6987951807229, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI19921772, Length=450, Percent_Identity=27.1111111111111, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24665395, Length=418, Percent_Identity=21.5311004784689, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46207; Mature: 46075

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQINVTRLPSGLTVVTERMERVETVSFGAYVAAGTCNEHAEENGVSHFLEHMAFKGTD
CCCCCCEEECCCCHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHCCHHHHHHHHHCCCCC
SRTAAGIAEEIENVGGHINAYTAREHTAYYVKLLKEDLALGADIIGDILTHSSFAPDEVE
CHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RERGVILQEIGQANDTPDDIIFDHFQETAFPEQPMGRPTLGTEPLIQDMSRETLMRYMRT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HYTTANTVIAAAGNLHHADVVALAERHFRDLPALDSSTGFDSRYLGGEFRKEKELDQAHV
HCCHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHCCCEE
VLGFPSVGYGDPDYYPVLLLSTLLGGGMSSRLFQEIREKRGLVYSVYSFNAPFRDGGLFG
EEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEE
IYAGTGEDQADELIPVTLEELRKVQGHVGQDELNRARAQLKSSLLMSLESTGSRCEQLAR
EEECCCCCCCHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLQVFGRLIPTAETVERINAVTIADVRRVATRLFRGKPTLASLGPVRNIPGIAAIAEALA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHC
A
C
>Mature Secondary Structure 
TDQINVTRLPSGLTVVTERMERVETVSFGAYVAAGTCNEHAEENGVSHFLEHMAFKGTD
CCCCCEEECCCCHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHCCHHHHHHHHHCCCCC
SRTAAGIAEEIENVGGHINAYTAREHTAYYVKLLKEDLALGADIIGDILTHSSFAPDEVE
CHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RERGVILQEIGQANDTPDDIIFDHFQETAFPEQPMGRPTLGTEPLIQDMSRETLMRYMRT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HYTTANTVIAAAGNLHHADVVALAERHFRDLPALDSSTGFDSRYLGGEFRKEKELDQAHV
HCCHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHHHCCCEE
VLGFPSVGYGDPDYYPVLLLSTLLGGGMSSRLFQEIREKRGLVYSVYSFNAPFRDGGLFG
EEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEE
IYAGTGEDQADELIPVTLEELRKVQGHVGQDELNRARAQLKSSLLMSLESTGSRCEQLAR
EEECCCCCCCHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLQVFGRLIPTAETVERINAVTIADVRRVATRLFRGKPTLASLGPVRNIPGIAAIAEALA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA