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The map label for this gene is suhB [H]

Identifier: 162147659

GI number: 162147659

Start: 1910557

End: 1911381

Strand: Reverse

Name: suhB [H]

Synonym: GDI_1875

Alternate gene names: 162147659

Gene position: 1911381-1910557 (Counterclockwise)

Preceding gene: 162147660

Following gene: 162147658

Centisome position: 48.46

GC content: 71.39

Gene sequence:

>825_bases
ATGTCCCTGGCCACGCCCCTGCCCCCGCATGACGCCGACCGGCTGGTCGCGGCGGCCATGGCCGCGGCCGACGTCGCGGG
CTGCGTCATCCGCCCGTTCTTTCGCATGGGCGTCGCCGCCGACGACAAGAGCGACCAGAGCCCCGTGACCATCGCCGACC
GCACGGCCGAGCGCGCCATTCGCGCCGTGCTGGCCGAACGCCTGCCGGACCACGCAGTCCTGGGCGAGGAATTCGGCCTG
GAACGCGGTGGTGCGCGTTATTGCTGGGTGATCGACCCGGTGGACGGCACCCGCGCCTTCCTGACCGGGCGGCCGATCTT
CGGCACGCTGATCGCGTTGCTTCAGGACGGGGAGCCGGTGCTGGGCATCATCGACCAGCCCGTTACCGGGGAACGCTGGA
TCGGCGTGCGGGGCCGGCCCACGCGTTATGAATCCCGCTGGCCCGGCACCGCCGGCACCCGCGAATGCCCCGAAATCGGC
CTGGCGGAACTGTCCTGCACCTCGCCCGAGATGATCGCCGACGCGCCCACACCGCATTGGGATGCCCTGCGCCGGCACGC
AAAGCGTGTCACGTGGGGTGGAGACTGCTACAGTTACGGCCTGCTGGCGCTGGGACAGGTCGACATCATCGCGGAATGCA
CGATGAAGATCTGGGACTGGGCCGCGCTGGTCCCGGTGATCGAGGGCGCGGGCGGCCGCGTCACCGACTGGCACGGCAGG
CCCCTGCACGCCGACAGCGACGGCACGGTACTGGCGGTGGGCGACCCGGCGCTGCTGCCCGGCGTGGTGTCGCTGCTGAC
CACGGGCAGCCCCAAGCACGCATGA

Upstream 100 bases:

>100_bases
CCCCCGGCACCCGCATGGCCTTCCCCGGCGTGGCGGATGCCGCCGACCGGGCCGCGATCATCGCCTTCCTGCACACGCTT
TCGGACGGAGCCCACTGACC

Downstream 100 bases:

>100_bases
TGGCGCCGGCCTGACGGCCGCACCACATGGCACCGATGTCCACGTCGCCCCTAGGCATTTATCCGTCGATCGGATAGGAG
CGACATCTTCTTCGAATAGG

Product: inositol-1-monophosphatase

Products: NA

Alternate protein names: HolPase; Histidinol-phosphate phosphatase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSLATPLPPHDADRLVAAAMAAADVAGCVIRPFFRMGVAADDKSDQSPVTIADRTAERAIRAVLAERLPDHAVLGEEFGL
ERGGARYCWVIDPVDGTRAFLTGRPIFGTLIALLQDGEPVLGIIDQPVTGERWIGVRGRPTRYESRWPGTAGTRECPEIG
LAELSCTSPEMIADAPTPHWDALRRHAKRVTWGGDCYSYGLLALGQVDIIAECTMKIWDWAALVPVIEGAGGRVTDWHGR
PLHADSDGTVLAVGDPALLPGVVSLLTTGSPKHA

Sequences:

>Translated_274_residues
MSLATPLPPHDADRLVAAAMAAADVAGCVIRPFFRMGVAADDKSDQSPVTIADRTAERAIRAVLAERLPDHAVLGEEFGL
ERGGARYCWVIDPVDGTRAFLTGRPIFGTLIALLQDGEPVLGIIDQPVTGERWIGVRGRPTRYESRWPGTAGTRECPEIG
LAELSCTSPEMIADAPTPHWDALRRHAKRVTWGGDCYSYGLLALGQVDIIAECTMKIWDWAALVPVIEGAGGRVTDWHGR
PLHADSDGTVLAVGDPALLPGVVSLLTTGSPKHA
>Mature_273_residues
SLATPLPPHDADRLVAAAMAAADVAGCVIRPFFRMGVAADDKSDQSPVTIADRTAERAIRAVLAERLPDHAVLGEEFGLE
RGGARYCWVIDPVDGTRAFLTGRPIFGTLIALLQDGEPVLGIIDQPVTGERWIGVRGRPTRYESRWPGTAGTRECPEIGL
AELSCTSPEMIADAPTPHWDALRRHAKRVTWGGDCYSYGLLALGQVDIIAECTMKIWDWAALVPVIEGAGGRVTDWHGRP
LHADSDGTVLAVGDPALLPGVVSLLTTGSPKHA

Specific function: Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Localized On The Inner Face Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=211, Percent_Identity=31.2796208530806, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202570, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357329, Length=236, Percent_Identity=26.271186440678, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011809
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 29298; Mature: 29167

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLATPLPPHDADRLVAAAMAAADVAGCVIRPFFRMGVAADDKSDQSPVTIADRTAERAI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
RAVLAERLPDHAVLGEEFGLERGGARYCWVIDPVDGTRAFLTGRPIFGTLIALLQDGEPV
HHHHHHHCCCHHHCCHHHCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCE
LGIIDQPVTGERWIGVRGRPTRYESRWPGTAGTRECPEIGLAELSCTSPEMIADAPTPHW
EEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCCCCCCH
DALRRHAKRVTWGGDCYSYGLLALGQVDIIAECTMKIWDWAALVPVIEGAGGRVTDWHGR
HHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC
PLHADSDGTVLAVGDPALLPGVVSLLTTGSPKHA
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLATPLPPHDADRLVAAAMAAADVAGCVIRPFFRMGVAADDKSDQSPVTIADRTAERAI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHH
RAVLAERLPDHAVLGEEFGLERGGARYCWVIDPVDGTRAFLTGRPIFGTLIALLQDGEPV
HHHHHHHCCCHHHCCHHHCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHCCCCE
LGIIDQPVTGERWIGVRGRPTRYESRWPGTAGTRECPEIGLAELSCTSPEMIADAPTPHW
EEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHCCCCCCCH
DALRRHAKRVTWGGDCYSYGLLALGQVDIIAECTMKIWDWAALVPVIEGAGGRVTDWHGR
HHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC
PLHADSDGTVLAVGDPALLPGVVSLLTTGSPKHA
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8626508 [H]