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The map label for this gene is trpS [H]

Identifier: 162147639

GI number: 162147639

Start: 1892886

End: 1893881

Strand: Reverse

Name: trpS [H]

Synonym: GDI_1855

Alternate gene names: 162147639

Gene position: 1893881-1892886 (Counterclockwise)

Preceding gene: 162147640

Following gene: 162147638

Centisome position: 48.02

GC content: 66.67

Gene sequence:

>996_bases
ATGCAACGCATCTTTTCCGGCATTCAGCCGACCGGCATTCCGCAATTGGGCAACTATCTGGGCGCGATCCGCAACTGGGT
CGCGCTGCAGCAGGACCATGAGTGCATCTTCTGCCTCGTGGACCTGCACGCCATCACGGTGTGGCAGGACCCTGAGGCGC
TGCGCCAGCAGACGCTGGCCCAGACCGCCGTGCTGTTGGCGGCGGGGATCGACCCCAAGGCCCATATCCTGTTCAACCAG
TCCGCCGTCAGCGCCCATGCCCGGCTGGGCTGGATCTTCAACTGCGTGTCGCGCCTGGGCTGGCTGAACCGGATGACGCA
GTTCAAGGACAAGGCCGGCAAGGACCGCGAAAACCATTCGGCCGGCCTGTATATCTACCCCAACCTGATGGCGGCCGACA
TCCTGGCCTACAAGGCGACGCGGGTGCCCGTCGGGGACGACCAGCGCCAGCATCTGGAACTGGCTAACGACATCGCACAG
AAATTCAACCACGATTACGGCGTGGACTTCTTCCCGGCGATCGAGGCCCTGATTCCTGCCGGCGCCGCGCGGGTCATGAG
CCTGCGCGACGGCACCAAGAAGATGTCCAAATCCGATCCGTCGGCCCAGAGCCGGATCGAGATGACCGACGACGCCGACG
CGATCGCGCTGAAGATCCGCCGGGCCAAGACCGACCCCGAACCCCTGCCCACCGACCCCGCCGACCTGCAATCACGCCCC
GAGGCCCGGAACCTGGTGGAGATCTATGCCGTTCTGAGCGGCATGACGGTGGCGGACGTGCTGGCCCGCCATGGCGGCAC
GGGGTTCGGGCCGTTCAAGGCGGCGCTGACCGACGTGCTGGTCGCGGCCGTGACGCCCATCGGGGCGGAAACCAGGCGCC
TGCTGGACGCCCCGGAGCACCTGCAGGCCGTGCTGCGCGAAGGGGCCGCACGCGCGAACGCCATTGCCGAGCCGATCGTC
AGCGAGGTCGAACGCCTCGTCGGCTTCCTGAAATAG

Upstream 100 bases:

>100_bases
AAGATCCAGCTTCTGGGTGTCTCCAAGCCGCAGTAGCCGGCATGTCCCCCCGGACCGGACGGCTTGACCGGACGGGGGGA
AACGCCTGAAAAGAACGGCC

Downstream 100 bases:

>100_bases
AGACACATTATCGGGAGCATCCCCATGCGCCAGGCCCTGCATCGCCTCAGCATCGCCACCCACGGCAAGGGCCTGGTGAT
GTTCACGCGCGACGTCCTGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MQRIFSGIQPTGIPQLGNYLGAIRNWVALQQDHECIFCLVDLHAITVWQDPEALRQQTLAQTAVLLAAGIDPKAHILFNQ
SAVSAHARLGWIFNCVSRLGWLNRMTQFKDKAGKDRENHSAGLYIYPNLMAADILAYKATRVPVGDDQRQHLELANDIAQ
KFNHDYGVDFFPAIEALIPAGAARVMSLRDGTKKMSKSDPSAQSRIEMTDDADAIALKIRRAKTDPEPLPTDPADLQSRP
EARNLVEIYAVLSGMTVADVLARHGGTGFGPFKAALTDVLVAAVTPIGAETRRLLDAPEHLQAVLREGAARANAIAEPIV
SEVERLVGFLK

Sequences:

>Translated_331_residues
MQRIFSGIQPTGIPQLGNYLGAIRNWVALQQDHECIFCLVDLHAITVWQDPEALRQQTLAQTAVLLAAGIDPKAHILFNQ
SAVSAHARLGWIFNCVSRLGWLNRMTQFKDKAGKDRENHSAGLYIYPNLMAADILAYKATRVPVGDDQRQHLELANDIAQ
KFNHDYGVDFFPAIEALIPAGAARVMSLRDGTKKMSKSDPSAQSRIEMTDDADAIALKIRRAKTDPEPLPTDPADLQSRP
EARNLVEIYAVLSGMTVADVLARHGGTGFGPFKAALTDVLVAAVTPIGAETRRLLDAPEHLQAVLREGAARANAIAEPIV
SEVERLVGFLK
>Mature_331_residues
MQRIFSGIQPTGIPQLGNYLGAIRNWVALQQDHECIFCLVDLHAITVWQDPEALRQQTLAQTAVLLAAGIDPKAHILFNQ
SAVSAHARLGWIFNCVSRLGWLNRMTQFKDKAGKDRENHSAGLYIYPNLMAADILAYKATRVPVGDDQRQHLELANDIAQ
KFNHDYGVDFFPAIEALIPAGAARVMSLRDGTKKMSKSDPSAQSRIEMTDDADAIALKIRRAKTDPEPLPTDPADLQSRP
EARNLVEIYAVLSGMTVADVLARHGGTGFGPFKAALTDVLVAAVTPIGAETRRLLDAPEHLQAVLREGAARANAIAEPIV
SEVERLVGFLK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=45.9214501510574, Blast_Score=291, Evalue=4e-79,
Organism=Homo sapiens, GI41352700, Length=178, Percent_Identity=55.0561797752809, Blast_Score=201, Evalue=6e-52,
Organism=Escherichia coli, GI1789786, Length=327, Percent_Identity=44.0366972477064, Blast_Score=288, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI71982800, Length=332, Percent_Identity=36.7469879518072, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71982793, Length=332, Percent_Identity=36.7469879518072, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=347, Percent_Identity=37.1757925072046, Blast_Score=213, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24666151, Length=334, Percent_Identity=38.0239520958084, Blast_Score=220, Evalue=9e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36184; Mature: 36184

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIFSGIQPTGIPQLGNYLGAIRNWVALQQDHECIFCLVDLHAITVWQDPEALRQQTLA
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHEEEEECCHHHHHHHHHH
QTAVLLAAGIDPKAHILFNQSAVSAHARLGWIFNCVSRLGWLNRMTQFKDKAGKDRENHS
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGLYIYPNLMAADILAYKATRVPVGDDQRQHLELANDIAQKFNHDYGVDFFPAIEALIPA
CCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GAARVMSLRDGTKKMSKSDPSAQSRIEMTDDADAIALKIRRAKTDPEPLPTDPADLQSRP
CHHHHHHHHHHHHHHHCCCCCHHHCEECCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCC
EARNLVEIYAVLSGMTVADVLARHGGTGFGPFKAALTDVLVAAVTPIGAETRRLLDAPEH
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHH
LQAVLREGAARANAIAEPIVSEVERLVGFLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRIFSGIQPTGIPQLGNYLGAIRNWVALQQDHECIFCLVDLHAITVWQDPEALRQQTLA
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHEEEEECCHHHHHHHHHH
QTAVLLAAGIDPKAHILFNQSAVSAHARLGWIFNCVSRLGWLNRMTQFKDKAGKDRENHS
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGLYIYPNLMAADILAYKATRVPVGDDQRQHLELANDIAQKFNHDYGVDFFPAIEALIPA
CCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
GAARVMSLRDGTKKMSKSDPSAQSRIEMTDDADAIALKIRRAKTDPEPLPTDPADLQSRP
CHHHHHHHHHHHHHHHCCCCCHHHCEECCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCCC
EARNLVEIYAVLSGMTVADVLARHGGTGFGPFKAALTDVLVAAVTPIGAETRRLLDAPEH
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHH
LQAVLREGAARANAIAEPIVSEVERLVGFLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]