Click here to switch to the map view.

The map label for this gene is mcpA [H]

Identifier: 162147466

GI number: 162147466

Start: 1706560

End: 1708056

Strand: Direct

Name: mcpA [H]

Synonym: GDI_1682

Alternate gene names: 162147466

Gene position: 1706560-1708056 (Clockwise)

Preceding gene: 162147465

Following gene: 162147467

Centisome position: 43.27

GC content: 64.93

Gene sequence:

>1497_bases
ATGCTGAAGTGGCTGAACCAGGACGCCCCGCTGCGCGTCAAGATCAGGATAGCTATGCTGTGTCTGGAAGCTTACCTGAT
GCTCCAGATCATCATCGAGGCAGTAGGCTATCTCAATCACGAGCCGGTCGAGCATATGTTCCTGATGAACATGAGCGCGC
TCGGCTTTGGTGAAATCGTCGTCTATGCGCTGTGGTACGCCTTGACGATCGGGGTCACGACCCCTCTGGAGCAGATCGTC
GATATCGGCGAGAGTCTGGGGCGTGGCGAGATCAGTGGTGATGTTCCGTTCCTCGACAACAAGGACGGGGTGGGCCGCCT
GGCCCGCGTGATGGTCTCGTTCGCCCGGAGCGTGCGGGAACAGAGCGAGGCCAAGTCGCGCCAGGATGCGATGGCCGAGG
AAATCAAGGAATCGCTCAAGCGCAGCCAGGAACGCGACCGGCAGACGCACGAGGTCATCGAATCTCTCGGCTCGGCCCTG
GCGGATATGGCCAAGGGCGACCTGCGGGTGCGGATCTCGGGCGCGATCTTCGACGGCGAATTCACGCCGCTGCGTGACGC
GTTCAATCACTCGGCGTTGCGCCTGAGCGAGGCGCTGCGGGCCGTGGCCAGCAACTCCGACCTGATTGCGACCGGCGCCA
CCGAGATCTCGACCGCTTCCGACGACCTTGCGAAGCGGACCGAGAAGCAGGCGGCGAATCTCGGCCAGGCGGCGGCGTCC
GTCCGCACCGTCACCGACGGCGTGCAGCGCAACGCGAAGGCCTGCGCGGAGGCCAATGCCGAGACGAGACAGGCTCAGGA
GAAGGTCAAGTCGGCCACCGGGGTCATGGCCGAAACGACCGAGGCGATGGACGGGATCAAGAAGTCGTCCGACGCGATCG
GCGAGATCATCTCGGTCATCGACGGCATCGCGTTCCAGACCAACGTCCTGGCCCTGAACGCGGGCGTCGAGGCGGCCCGT
GCCGGTGACGCGGGACGCGGCTTCGCGGTGGTGGCGCAGGAAGTGCGGTCCCTGGCCGAGCAGTCGGCCAAGTCGGCGCG
AGAGATCAAGCGACTGATTTCCGTTTCCGCCGATCAGGTCGTCAAGGGCGTCGACCTGGTGCAGCAGACCGGTCATTACT
TGGCCGAGTTCGCGGTAAGCACGGAAAACATCGCGACCCGGGTCGGGGAGATCTCGGTCTCCACGCAGGACCAGGCCCAG
CGCCTGTCCGAGATCACGGCCTCGATCGGCGACATGGACCAGGTGACGCAGCAGAATGCCGCCATGGTCGAGCAGACGAC
GGCTGCCAGCCACAACCTGACCGCCGAGACCAGGACGCTGGCGCAGACGCTCAGCCGGTTCAAGATCGGCATGGGGCGAG
AAAACGGGATTGCCGGCCAGAGTCCCGCGAAGCTTCCGCCCGCGCGGGCGGTCGTCAAGCCAAGCCGGGTCGCGGAAACC
GCGCTCGCCACGCCACTTTCGACAACGTCTTCCGACAGTGGATGGGAGGAATTCTGA

Upstream 100 bases:

>100_bases
AAGGCCATCGGCACCAGACGTACTATATGAGGCGGGAATTGGTGCGCTGGCGCTTCCATGCGTGGCACCCCGTGAAAACA
AGAAGGGAAGTTGCATCCGC

Downstream 100 bases:

>100_bases
TGGCGGCCGCTTCCTTGTCCACATCTATCGAGTCCGGTGCCGGTCCCGCGGTCTGCGTGACGCTGCCCGAGCGTCTGGAT
ACCGCCGCAGCCTTTGCGCT

Product: chemoreceptor mcpA (methyl-accepting chemotaxis protein)

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MLKWLNQDAPLRVKIRIAMLCLEAYLMLQIIIEAVGYLNHEPVEHMFLMNMSALGFGEIVVYALWYALTIGVTTPLEQIV
DIGESLGRGEISGDVPFLDNKDGVGRLARVMVSFARSVREQSEAKSRQDAMAEEIKESLKRSQERDRQTHEVIESLGSAL
ADMAKGDLRVRISGAIFDGEFTPLRDAFNHSALRLSEALRAVASNSDLIATGATEISTASDDLAKRTEKQAANLGQAAAS
VRTVTDGVQRNAKACAEANAETRQAQEKVKSATGVMAETTEAMDGIKKSSDAIGEIISVIDGIAFQTNVLALNAGVEAAR
AGDAGRGFAVVAQEVRSLAEQSAKSAREIKRLISVSADQVVKGVDLVQQTGHYLAEFAVSTENIATRVGEISVSTQDQAQ
RLSEITASIGDMDQVTQQNAAMVEQTTAASHNLTAETRTLAQTLSRFKIGMGRENGIAGQSPAKLPPARAVVKPSRVAET
ALATPLSTTSSDSGWEEF

Sequences:

>Translated_498_residues
MLKWLNQDAPLRVKIRIAMLCLEAYLMLQIIIEAVGYLNHEPVEHMFLMNMSALGFGEIVVYALWYALTIGVTTPLEQIV
DIGESLGRGEISGDVPFLDNKDGVGRLARVMVSFARSVREQSEAKSRQDAMAEEIKESLKRSQERDRQTHEVIESLGSAL
ADMAKGDLRVRISGAIFDGEFTPLRDAFNHSALRLSEALRAVASNSDLIATGATEISTASDDLAKRTEKQAANLGQAAAS
VRTVTDGVQRNAKACAEANAETRQAQEKVKSATGVMAETTEAMDGIKKSSDAIGEIISVIDGIAFQTNVLALNAGVEAAR
AGDAGRGFAVVAQEVRSLAEQSAKSAREIKRLISVSADQVVKGVDLVQQTGHYLAEFAVSTENIATRVGEISVSTQDQAQ
RLSEITASIGDMDQVTQQNAAMVEQTTAASHNLTAETRTLAQTLSRFKIGMGRENGIAGQSPAKLPPARAVVKPSRVAET
ALATPLSTTSSDSGWEEF
>Mature_498_residues
MLKWLNQDAPLRVKIRIAMLCLEAYLMLQIIIEAVGYLNHEPVEHMFLMNMSALGFGEIVVYALWYALTIGVTTPLEQIV
DIGESLGRGEISGDVPFLDNKDGVGRLARVMVSFARSVREQSEAKSRQDAMAEEIKESLKRSQERDRQTHEVIESLGSAL
ADMAKGDLRVRISGAIFDGEFTPLRDAFNHSALRLSEALRAVASNSDLIATGATEISTASDDLAKRTEKQAANLGQAAAS
VRTVTDGVQRNAKACAEANAETRQAQEKVKSATGVMAETTEAMDGIKKSSDAIGEIISVIDGIAFQTNVLALNAGVEAAR
AGDAGRGFAVVAQEVRSLAEQSAKSAREIKRLISVSADQVVKGVDLVQQTGHYLAEFAVSTENIATRVGEISVSTQDQAQ
RLSEITASIGDMDQVTQQNAAMVEQTTAASHNLTAETRTLAQTLSRFKIGMGRENGIAGQSPAKLPPARAVVKPSRVAET
ALATPLSTTSSDSGWEEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=289, Percent_Identity=40.4844290657439, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1788195, Length=326, Percent_Identity=37.7300613496933, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1788194, Length=266, Percent_Identity=42.8571428571429, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1787690, Length=241, Percent_Identity=39.8340248962656, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1789453, Length=229, Percent_Identity=36.2445414847162, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 53350; Mature: 53350

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKWLNQDAPLRVKIRIAMLCLEAYLMLQIIIEAVGYLNHEPVEHMFLMNMSALGFGEIV
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHH
VYALWYALTIGVTTPLEQIVDIGESLGRGEISGDVPFLDNKDGVGRLARVMVSFARSVRE
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QSEAKSRQDAMAEEIKESLKRSQERDRQTHEVIESLGSALADMAKGDLRVRISGAIFDGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCC
FTPLRDAFNHSALRLSEALRAVASNSDLIATGATEISTASDDLAKRTEKQAANLGQAAAS
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHH
VRTVTDGVQRNAKACAEANAETRQAQEKVKSATGVMAETTEAMDGIKKSSDAIGEIISVI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGIAFQTNVLALNAGVEAARAGDAGRGFAVVAQEVRSLAEQSAKSAREIKRLISVSADQV
HCHHHHHCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VKGVDLVQQTGHYLAEFAVSTENIATRVGEISVSTQDQAQRLSEITASIGDMDQVTQQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AMVEQTTAASHNLTAETRTLAQTLSRFKIGMGRENGIAGQSPAKLPPARAVVKPSRVAET
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHH
ALATPLSTTSSDSGWEEF
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKWLNQDAPLRVKIRIAMLCLEAYLMLQIIIEAVGYLNHEPVEHMFLMNMSALGFGEIV
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHH
VYALWYALTIGVTTPLEQIVDIGESLGRGEISGDVPFLDNKDGVGRLARVMVSFARSVRE
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QSEAKSRQDAMAEEIKESLKRSQERDRQTHEVIESLGSALADMAKGDLRVRISGAIFDGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCC
FTPLRDAFNHSALRLSEALRAVASNSDLIATGATEISTASDDLAKRTEKQAANLGQAAAS
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHH
VRTVTDGVQRNAKACAEANAETRQAQEKVKSATGVMAETTEAMDGIKKSSDAIGEIISVI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGIAFQTNVLALNAGVEAARAGDAGRGFAVVAQEVRSLAEQSAKSAREIKRLISVSADQV
HCHHHHHCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VKGVDLVQQTGHYLAEFAVSTENIATRVGEISVSTQDQAQRLSEITASIGDMDQVTQQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AMVEQTTAASHNLTAETRTLAQTLSRFKIGMGRENGIAGQSPAKLPPARAVVKPSRVAET
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHH
ALATPLSTTSSDSGWEEF
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]