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The map label for this gene is mcpA [H]

Identifier: 162147446

GI number: 162147446

Start: 1684090

End: 1686330

Strand: Reverse

Name: mcpA [H]

Synonym: GDI_1662

Alternate gene names: 162147446

Gene position: 1686330-1684090 (Counterclockwise)

Preceding gene: 162147447

Following gene: 162147440

Centisome position: 42.76

GC content: 63.45

Gene sequence:

>2241_bases
ATGACGCCCACCCAACAGCCGCATTTTTTCAATTCCCTCTCCAGGAAGCTGATCGGCACAGCCGGGCTGGCGTTCGCCGT
TATTCTTTGCGGCGCGATCGCACTGTTGGCCTGGACGACCAAGACACGTGTCGAGCGCTATGTCTTTGCCCAGGCCGATG
CACAGGCGCAAATAGCCGCCAACGAAGTCGCAACAAGGCTGACGGCGCAAAATTCCGCGGCGAATTTCATGAGCGGCGCC
GTAGAGGCCGCACACGAGGCCGGGTTGCCCGACCGTGGCCTGATCGTCGCCATGCTGCGGATGAGCGAAAAACGGCTTCC
CGATCTTTTCGGCACCTGGATGGAGGAGGCGCCGCTGGGCCTGGACGGGACCACCAACCCCCATGCGCCAGGCGACAACG
CGGACGGCGTCTTCAATCCGTACTGGATGAGAGGAAGCGACGGCAAGCTCACGTTCTCAGCGCTGCCGGCCCATTATTCG
CAGACATGGTATACGCTTCCGATGTCCCAGGGCCGCGGCATCATCACCGAGCCCTATGTCGATGAGGGCAGCGGGATCGA
GATGGTCTCGTTTGCCTATCCTGTCAAATTTGACGGCAAATCAGTCGGCGTCACCGGAATCGACGCGCCGCTGGACCGGC
TTTCCCGAATGCTGGCGACCATGAGACCATTCGGCAGCGGTCATGTCATGCTGGTTTCCGGCAGCGGCACCTGGGTGACC
AACCCGGATGCGCATCTTCTGATGACGGCCTACGCGGGAGAAGGCGCCAGGGAACTCGCGGCCGCCATCGCGGACGGTCG
GTCGCGTATCCTGCACAAGATCCACGGTGGAACCATCGAACGCGTCATCTATCCATTTGCCATACCGGATCTGAAAACGA
CCTGGGCCATCATCGTCGATGTCCCCGAAGACGTCCTGGAAGCACCGGTCCGGCAGGATCTGCAGGTGATGATCATCGGT
GGGCTGATCACGGTCCTTCTTGTGCTGGGAACGCTCTACTTCATGGTTACCGTGCTGGTGCGCCGCCCGATGGAATCCCT
GCTGGCGTCTGTCGAGACACTCAGCCAGGGGGATTACGCCCGCCCCGTAACGGGCCGGCAGCGGCACGATGAAACCGGCA
CCATCGCGACTGCCCTGGACGGCTTCCGCCTTGCCCTGGCCGACGGCCGGCGCAACGAAGAGGCCGCGACAGCGGAACGA
CGCAAGGCCGAACGGCTTCGTGCCGAGACCCAGGCTGCCCAGGCCGCCAAGGCTGCCGAATTGAACAAGGTCGTCACGAA
ACTGGGACACGGGCTGGAACGCCTCTCCTCGGGGGACCTGCTCTTTCGCCTGGATGAACGTTTCGCCCCCGAATACGAGA
CGCTTCGCGGCGATTTCAACACCGCGATGGACAAGCTTCAGGAGACCATATCGGCGATAGCGTCCGCGGCAGGCGGTGTG
ACATCCGATTCCACGCAGATCGCCACGGCCACCGAGGATCTGTCCCGCCGGACCGAACAGCAGGCCGCCAGCCTGGAGGA
GACCACCGCTGCCCTGCACGAAATCACCGTGACGGTCCGCAAGACCGCGCAGGGCGCCTCCAATGCGGACACCCTGGTCA
GCAGCGCCTCAACCGATGCGGCGCATTCCGGCGCGGTCGTGAAGGAAACCGTGGCCGCCATGAACGGGATTCAACACGCG
GCGAGTGAAATCCGCCATATTCTCGGGCTGATCGACGAAATCGCATTCCAGACCAATCTTCTGGCGGTCAGCGCCGCGGT
CGAGGCCGCCCGGGCGGGCCAGGCCGGCCGAAGCTTCACGGTCGTCGCCACCGAAGTGCGGGCCCTGTCCGACCGGTCGG
CCGAAGCCGCCAGACAGATCAAGGACCTGATCGCCACGTCGGACGAGCAGATCGATCGCGGCGTGAAGCTGGTCGGCGAA
ACCGGCAAGGCACTGGAGCGCATCATCGGCCAGGTGGGACGGTTGAGCGAATTCGTCTCCAGGATCTCGTCAGCGGCGCA
AGAGCAGGCAACGGGACTGAACCAGGTCAATATCGCGATGGGTCAGATGGATCGGGTGACACAGCAAAACGCGGCGATGT
CGGAACAGTCGCGGGCAGCGTCCCATTCCCTGAAGCAGGAGGCCGGAACATTGGCCCGCCTCGTCGGGGAATTCCAGATC
GACGAATTGAAGACGCCTCGTCGGGCAACGCGCCCGGGCATCAGGACTGCGGAGCTTGCAGGGTCCATACGGAACGACTG
A

Upstream 100 bases:

>100_bases
GTGCGTATAGTCGTCCCTGTTCGGATCAGATTGACGTACGAAATGAATTATTGAAGGTTGTTTCCACGACGAAATGGAAT
CAATCCAGAGGTGTTCGCTT

Downstream 100 bases:

>100_bases
GGGGCCTCGCCCCTGCACGTTGCGTTCCCCAAAAACGAAAAATCCAGGGCTCTGCCCTGGACCCGCCAAACGCCGCTGGC
CTTTGGAAACCCTCTGAAGG

Product: chemoreceptor mcpA (methyl-accepting chemotaxis protein)

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MTPTQQPHFFNSLSRKLIGTAGLAFAVILCGAIALLAWTTKTRVERYVFAQADAQAQIAANEVATRLTAQNSAANFMSGA
VEAAHEAGLPDRGLIVAMLRMSEKRLPDLFGTWMEEAPLGLDGTTNPHAPGDNADGVFNPYWMRGSDGKLTFSALPAHYS
QTWYTLPMSQGRGIITEPYVDEGSGIEMVSFAYPVKFDGKSVGVTGIDAPLDRLSRMLATMRPFGSGHVMLVSGSGTWVT
NPDAHLLMTAYAGEGARELAAAIADGRSRILHKIHGGTIERVIYPFAIPDLKTTWAIIVDVPEDVLEAPVRQDLQVMIIG
GLITVLLVLGTLYFMVTVLVRRPMESLLASVETLSQGDYARPVTGRQRHDETGTIATALDGFRLALADGRRNEEAATAER
RKAERLRAETQAAQAAKAAELNKVVTKLGHGLERLSSGDLLFRLDERFAPEYETLRGDFNTAMDKLQETISAIASAAGGV
TSDSTQIATATEDLSRRTEQQAASLEETTAALHEITVTVRKTAQGASNADTLVSSASTDAAHSGAVVKETVAAMNGIQHA
ASEIRHILGLIDEIAFQTNLLAVSAAVEAARAGQAGRSFTVVATEVRALSDRSAEAARQIKDLIATSDEQIDRGVKLVGE
TGKALERIIGQVGRLSEFVSRISSAAQEQATGLNQVNIAMGQMDRVTQQNAAMSEQSRAASHSLKQEAGTLARLVGEFQI
DELKTPRRATRPGIRTAELAGSIRND

Sequences:

>Translated_746_residues
MTPTQQPHFFNSLSRKLIGTAGLAFAVILCGAIALLAWTTKTRVERYVFAQADAQAQIAANEVATRLTAQNSAANFMSGA
VEAAHEAGLPDRGLIVAMLRMSEKRLPDLFGTWMEEAPLGLDGTTNPHAPGDNADGVFNPYWMRGSDGKLTFSALPAHYS
QTWYTLPMSQGRGIITEPYVDEGSGIEMVSFAYPVKFDGKSVGVTGIDAPLDRLSRMLATMRPFGSGHVMLVSGSGTWVT
NPDAHLLMTAYAGEGARELAAAIADGRSRILHKIHGGTIERVIYPFAIPDLKTTWAIIVDVPEDVLEAPVRQDLQVMIIG
GLITVLLVLGTLYFMVTVLVRRPMESLLASVETLSQGDYARPVTGRQRHDETGTIATALDGFRLALADGRRNEEAATAER
RKAERLRAETQAAQAAKAAELNKVVTKLGHGLERLSSGDLLFRLDERFAPEYETLRGDFNTAMDKLQETISAIASAAGGV
TSDSTQIATATEDLSRRTEQQAASLEETTAALHEITVTVRKTAQGASNADTLVSSASTDAAHSGAVVKETVAAMNGIQHA
ASEIRHILGLIDEIAFQTNLLAVSAAVEAARAGQAGRSFTVVATEVRALSDRSAEAARQIKDLIATSDEQIDRGVKLVGE
TGKALERIIGQVGRLSEFVSRISSAAQEQATGLNQVNIAMGQMDRVTQQNAAMSEQSRAASHSLKQEAGTLARLVGEFQI
DELKTPRRATRPGIRTAELAGSIRND
>Mature_745_residues
TPTQQPHFFNSLSRKLIGTAGLAFAVILCGAIALLAWTTKTRVERYVFAQADAQAQIAANEVATRLTAQNSAANFMSGAV
EAAHEAGLPDRGLIVAMLRMSEKRLPDLFGTWMEEAPLGLDGTTNPHAPGDNADGVFNPYWMRGSDGKLTFSALPAHYSQ
TWYTLPMSQGRGIITEPYVDEGSGIEMVSFAYPVKFDGKSVGVTGIDAPLDRLSRMLATMRPFGSGHVMLVSGSGTWVTN
PDAHLLMTAYAGEGARELAAAIADGRSRILHKIHGGTIERVIYPFAIPDLKTTWAIIVDVPEDVLEAPVRQDLQVMIIGG
LITVLLVLGTLYFMVTVLVRRPMESLLASVETLSQGDYARPVTGRQRHDETGTIATALDGFRLALADGRRNEEAATAERR
KAERLRAETQAAQAAKAAELNKVVTKLGHGLERLSSGDLLFRLDERFAPEYETLRGDFNTAMDKLQETISAIASAAGGVT
SDSTQIATATEDLSRRTEQQAASLEETTAALHEITVTVRKTAQGASNADTLVSSASTDAAHSGAVVKETVAAMNGIQHAA
SEIRHILGLIDEIAFQTNLLAVSAAVEAARAGQAGRSFTVVATEVRALSDRSAEAARQIKDLIATSDEQIDRGVKLVGET
GKALERIIGQVGRLSEFVSRISSAAQEQATGLNQVNIAMGQMDRVTQQNAAMSEQSRAASHSLKQEAGTLARLVGEFQID
ELKTPRRATRPGIRTAELAGSIRND

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=277, Percent_Identity=41.8772563176895, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI1788195, Length=298, Percent_Identity=40.2684563758389, Blast_Score=189, Evalue=7e-49,
Organism=Escherichia coli, GI1787690, Length=315, Percent_Identity=37.1428571428571, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788194, Length=300, Percent_Identity=37.3333333333333, Blast_Score=175, Evalue=8e-45,
Organism=Escherichia coli, GI1789453, Length=242, Percent_Identity=35.9504132231405, Blast_Score=151, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 79897; Mature: 79766

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTQQPHFFNSLSRKLIGTAGLAFAVILCGAIALLAWTTKTRVERYVFAQADAQAQIAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
NEVATRLTAQNSAANFMSGAVEAAHEAGLPDRGLIVAMLRMSEKRLPDLFGTWMEEAPLG
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCC
LDGTTNPHAPGDNADGVFNPYWMRGSDGKLTFSALPAHYSQTWYTLPMSQGRGIITEPYV
CCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCC
DEGSGIEMVSFAYPVKFDGKSVGVTGIDAPLDRLSRMLATMRPFGSGHVMLVSGSGTWVT
CCCCCCEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEE
NPDAHLLMTAYAGEGARELAAAIADGRSRILHKIHGGTIERVIYPFAIPDLKTTWAIIVD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCEEEEEEE
VPEDVLEAPVRQDLQVMIIGGLITVLLVLGTLYFMVTVLVRRPMESLLASVETLSQGDYA
CCHHHHHCHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
RPVTGRQRHDETGTIATALDGFRLALADGRRNEEAATAERRKAERLRAETQAAQAAKAAE
CCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNKVVTKLGHGLERLSSGDLLFRLDERFAPEYETLRGDFNTAMDKLQETISAIASAAGGV
HHHHHHHHHHHHHHHCCCCEEEEECHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
TSDSTQIATATEDLSRRTEQQAASLEETTAALHEITVTVRKTAQGASNADTLVSSASTDA
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
AHSGAVVKETVAAMNGIQHAASEIRHILGLIDEIAFQTNLLAVSAAVEAARAGQAGRSFT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VVATEVRALSDRSAEAARQIKDLIATSDEQIDRGVKLVGETGKALERIIGQVGRLSEFVS
EEHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
RISSAAQEQATGLNQVNIAMGQMDRVTQQNAAMSEQSRAASHSLKQEAGTLARLVGEFQI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELKTPRRATRPGIRTAELAGSIRND
HHCCCCCHHCCCCCCHHHHHCCCCCC
>Mature Secondary Structure 
TPTQQPHFFNSLSRKLIGTAGLAFAVILCGAIALLAWTTKTRVERYVFAQADAQAQIAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
NEVATRLTAQNSAANFMSGAVEAAHEAGLPDRGLIVAMLRMSEKRLPDLFGTWMEEAPLG
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCC
LDGTTNPHAPGDNADGVFNPYWMRGSDGKLTFSALPAHYSQTWYTLPMSQGRGIITEPYV
CCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCEEEEECCCCCCEECCCCC
DEGSGIEMVSFAYPVKFDGKSVGVTGIDAPLDRLSRMLATMRPFGSGHVMLVSGSGTWVT
CCCCCCEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEE
NPDAHLLMTAYAGEGARELAAAIADGRSRILHKIHGGTIERVIYPFAIPDLKTTWAIIVD
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCEEEEEEE
VPEDVLEAPVRQDLQVMIIGGLITVLLVLGTLYFMVTVLVRRPMESLLASVETLSQGDYA
CCHHHHHCHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
RPVTGRQRHDETGTIATALDGFRLALADGRRNEEAATAERRKAERLRAETQAAQAAKAAE
CCCCCCCCCCCCCCHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNKVVTKLGHGLERLSSGDLLFRLDERFAPEYETLRGDFNTAMDKLQETISAIASAAGGV
HHHHHHHHHHHHHHHCCCCEEEEECHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
TSDSTQIATATEDLSRRTEQQAASLEETTAALHEITVTVRKTAQGASNADTLVSSASTDA
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCC
AHSGAVVKETVAAMNGIQHAASEIRHILGLIDEIAFQTNLLAVSAAVEAARAGQAGRSFT
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VVATEVRALSDRSAEAARQIKDLIATSDEQIDRGVKLVGETGKALERIIGQVGRLSEFVS
EEHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
RISSAAQEQATGLNQVNIAMGQMDRVTQQNAAMSEQSRAASHSLKQEAGTLARLVGEFQI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELKTPRRATRPGIRTAELAGSIRND
HHCCCCCHHCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]