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The map label for this gene is mod1 [H]

Identifier: 162147413

GI number: 162147413

Start: 1639248

End: 1640882

Strand: Reverse

Name: mod1 [H]

Synonym: GDI_1628

Alternate gene names: 162147413

Gene position: 1640882-1639248 (Counterclockwise)

Preceding gene: 162147414

Following gene: 162147410

Centisome position: 41.6

GC content: 67.83

Gene sequence:

>1635_bases
ATGAACCGACCCGCCCGACATACCCTGCGGGGCACGGCACTGCTGAACGACCCGGCCTTCAACCGGGGAACCGCCTTTAC
GGCCGCGGAACGGCAGACCTACGGGCTGGAAGGCCTGCTGCCGCCGCAGATCGAAACGCTGGAACGGCAGGCCGAGCGGG
CTCTGCGTCACCTGGACGCCAAGCCGACGGATCTGGAACGCTATATCTACCTCGCGGCCCTGGTCGACCGGAACGAGACC
CTGTTCTACAAGGTGCTGATGTCCGACCCGGCGCGCTTCGTGCCGATCGTCTACGCCCCCACGCTGGGCGAGGCCTGCAA
GGCATTCAGCCACATCTATCGCCGCCCCCGGGGCATGTATATCAGCCTGGAGATGAAGGGCCGCATCGCGGACATCCTGC
GCAACTGGCCGGTGTCCGACGTGCGCTTCATCTGCGTCACCACCGGCGGGCGCATCCTGGGCCTGGGCGATATCGGCGCC
AACGGCATGGGCATTCCCATCGGCAAGCTGCAGCTCTACACCGCCTGTGGCGCCGTGCCGCCGCAGGTCACGCTGCCGAT
CCAGCTGGATATCGGCACCACCAACGCGGCGCTGCGGGCCGATCCGCTCTATCTGGGCCTGCGGCACGAACCCCCGCCGC
AGGCCGAACTCGACGCCTTCGTCGAGGAATTCGTGACGGCGGTGCAGGAGGTCTTTCCCGCCTGCTGCATCCATTTCGAG
GACTGGAAGGGCACGGACGCGATCCGCTACCTGGAGCGCTACCGGGAGCGGGTGCTGTGCTACAACGACGACATCCAGGG
CACGGCGTCGGTGACGCTGGCCGGGCTGGTCACGGCGCTGCGGATCAAGGGCGAAAAACTGTCCGACCAGACGGTGCTGT
TCCTGGGTGCCGGGTCGTCCGCGCTGGGCACGTCGGACCTTCTGGTCAAGGCGATGCAGGCCGAAGGCCTGTCGCAGGCC
GACGCCCGCGCCCGCATCACCATGATGGACGTCAAGGGGCTGGTCGAACCCTCGCGCACCGACCTGTCCGAGGAACAGCG
GCGTTACGCCCATGCGGCGGAGCCCACGCGCGACCTGATGGCCACCATCCGCCGCGTGCGGCCCAGCGTGCTGATCGGCG
TGTCCACCGTGGGCGGCGCCTTCACGCAGCCGGTCGTCGAACTGATGGCCGCGATCAATGCGCGGCCGATCATCTTTCCG
CTGTCGATCCCGCATTCGGAATGCTCGGCCGAACAGGCCTATGCCTGGTCCGACGGCCGGGCGCTGTACGCGGCCGGGGT
CCAGTTCCCGCAGGTCATGCGCGACGACCATGTCTTCCGCCCCGGGCAGGCCAATAATTTCTACATCTTCCCCGGGCTGG
GGCTGGCGGTCTATGCGACGCGTCCGCGCCTGATCCCCGACGCGCTGATCATCGAGGCCGCACACGCCCTGGCCGACCAG
GTCGACGTGACGGCGCAGGCGCGCGGCATGCTGTATCCGCCGCAGAACCAGATTCTCGAGGTCCAGGTCACGTCGGCCTG
CCGCCTTGCGGAATATCTCTTCGATGCCGGGCTGGCCACCGTGCCGCGTCCGGACGATATCCGGTCTTGGATCGAGGGCA
TGACCTACAGCCCGACCTACGCGCCGGACGCCTGA

Upstream 100 bases:

>100_bases
TCCCTGACGATCGTCGAGCGCTTCCCCGAGGCATGGCGCATCGTCGCCGTCAACGAACTGCCGGGGATCTGACGCCCGCT
TTTTATGGAGTAAAGCGACC

Downstream 100 bases:

>100_bases
GGGGGGAGGAAGGTCGGGCTCTGCCCGAACCCGCAAGGGGTCGCGGACCCCTTGACCCCTGTTCGTTTCAGGCCTGGCGG
TTTTCCAGCAGGCTGCGCCG

Product: malate dehydrogenase

Products: NA

Alternate protein names: NAD-ME 1 [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MNRPARHTLRGTALLNDPAFNRGTAFTAAERQTYGLEGLLPPQIETLERQAERALRHLDAKPTDLERYIYLAALVDRNET
LFYKVLMSDPARFVPIVYAPTLGEACKAFSHIYRRPRGMYISLEMKGRIADILRNWPVSDVRFICVTTGGRILGLGDIGA
NGMGIPIGKLQLYTACGAVPPQVTLPIQLDIGTTNAALRADPLYLGLRHEPPPQAELDAFVEEFVTAVQEVFPACCIHFE
DWKGTDAIRYLERYRERVLCYNDDIQGTASVTLAGLVTALRIKGEKLSDQTVLFLGAGSSALGTSDLLVKAMQAEGLSQA
DARARITMMDVKGLVEPSRTDLSEEQRRYAHAAEPTRDLMATIRRVRPSVLIGVSTVGGAFTQPVVELMAAINARPIIFP
LSIPHSECSAEQAYAWSDGRALYAAGVQFPQVMRDDHVFRPGQANNFYIFPGLGLAVYATRPRLIPDALIIEAAHALADQ
VDVTAQARGMLYPPQNQILEVQVTSACRLAEYLFDAGLATVPRPDDIRSWIEGMTYSPTYAPDA

Sequences:

>Translated_544_residues
MNRPARHTLRGTALLNDPAFNRGTAFTAAERQTYGLEGLLPPQIETLERQAERALRHLDAKPTDLERYIYLAALVDRNET
LFYKVLMSDPARFVPIVYAPTLGEACKAFSHIYRRPRGMYISLEMKGRIADILRNWPVSDVRFICVTTGGRILGLGDIGA
NGMGIPIGKLQLYTACGAVPPQVTLPIQLDIGTTNAALRADPLYLGLRHEPPPQAELDAFVEEFVTAVQEVFPACCIHFE
DWKGTDAIRYLERYRERVLCYNDDIQGTASVTLAGLVTALRIKGEKLSDQTVLFLGAGSSALGTSDLLVKAMQAEGLSQA
DARARITMMDVKGLVEPSRTDLSEEQRRYAHAAEPTRDLMATIRRVRPSVLIGVSTVGGAFTQPVVELMAAINARPIIFP
LSIPHSECSAEQAYAWSDGRALYAAGVQFPQVMRDDHVFRPGQANNFYIFPGLGLAVYATRPRLIPDALIIEAAHALADQ
VDVTAQARGMLYPPQNQILEVQVTSACRLAEYLFDAGLATVPRPDDIRSWIEGMTYSPTYAPDA
>Mature_544_residues
MNRPARHTLRGTALLNDPAFNRGTAFTAAERQTYGLEGLLPPQIETLERQAERALRHLDAKPTDLERYIYLAALVDRNET
LFYKVLMSDPARFVPIVYAPTLGEACKAFSHIYRRPRGMYISLEMKGRIADILRNWPVSDVRFICVTTGGRILGLGDIGA
NGMGIPIGKLQLYTACGAVPPQVTLPIQLDIGTTNAALRADPLYLGLRHEPPPQAELDAFVEEFVTAVQEVFPACCIHFE
DWKGTDAIRYLERYRERVLCYNDDIQGTASVTLAGLVTALRIKGEKLSDQTVLFLGAGSSALGTSDLLVKAMQAEGLSQA
DARARITMMDVKGLVEPSRTDLSEEQRRYAHAAEPTRDLMATIRRVRPSVLIGVSTVGGAFTQPVVELMAAINARPIIFP
LSIPHSECSAEQAYAWSDGRALYAAGVQFPQVMRDDHVFRPGQANNFYIFPGLGLAVYATRPRLIPDALIIEAAHALADQ
VDVTAQARGMLYPPQNQILEVQVTSACRLAEYLFDAGLATVPRPDDIRSWIEGMTYSPTYAPDA

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malic enzymes family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=541, Percent_Identity=45.1016635859519, Blast_Score=484, Evalue=1e-137,
Organism=Homo sapiens, GI62420882, Length=543, Percent_Identity=42.7255985267035, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI62420880, Length=543, Percent_Identity=42.7255985267035, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI239049447, Length=543, Percent_Identity=42.7255985267035, Blast_Score=465, Evalue=1e-131,
Organism=Homo sapiens, GI4505145, Length=539, Percent_Identity=43.2282003710575, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI270265879, Length=450, Percent_Identity=44.8888888888889, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI87081919, Length=541, Percent_Identity=39.0018484288355, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788806, Length=412, Percent_Identity=26.2135922330097, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17537199, Length=548, Percent_Identity=43.2481751824818, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322823, Length=562, Percent_Identity=36.2989323843416, Blast_Score=336, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24646386, Length=539, Percent_Identity=45.4545454545455, Blast_Score=470, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24646388, Length=539, Percent_Identity=45.4545454545455, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI281362672, Length=538, Percent_Identity=44.7955390334572, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI281362674, Length=538, Percent_Identity=44.7955390334572, Blast_Score=460, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21356279, Length=538, Percent_Identity=44.7955390334572, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI281363505, Length=525, Percent_Identity=38.8571428571429, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI78707236, Length=525, Percent_Identity=38.8571428571429, Blast_Score=421, Evalue=1e-118,
Organism=Drosophila melanogaster, GI281363503, Length=522, Percent_Identity=38.8888888888889, Blast_Score=417, Evalue=1e-116,
Organism=Drosophila melanogaster, GI78707232, Length=501, Percent_Identity=39.1217564870259, Blast_Score=410, Evalue=1e-114,
Organism=Drosophila melanogaster, GI78707242, Length=526, Percent_Identity=39.3536121673004, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI78707238, Length=526, Percent_Identity=39.3536121673004, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI78707240, Length=501, Percent_Identity=39.7205588822355, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19922384, Length=534, Percent_Identity=33.1460674157303, Blast_Score=308, Evalue=6e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR001891
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M [H]

EC number: =1.1.1.38 [H]

Molecular weight: Translated: 59846; Mature: 59846

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPARHTLRGTALLNDPAFNRGTAFTAAERQTYGLEGLLPPQIETLERQAERALRHLDA
CCCCCCCCEECEEEECCCCCCCCCEEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
KPTDLERYIYLAALVDRNETLFYKVLMSDPARFVPIVYAPTLGEACKAFSHIYRRPRGMY
CCCCHHHHEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEE
ISLEMKGRIADILRNWPVSDVRFICVTTGGRILGLGDIGANGMGIPIGKLQLYTACGAVP
EEEEECCHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEEEEHHHCCCC
PQVTLPIQLDIGTTNAALRADPLYLGLRHEPPPQAELDAFVEEFVTAVQEVFPACCIHFE
CCEEEEEEEECCCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEC
DWKGTDAIRYLERYRERVLCYNDDIQGTASVTLAGLVTALRIKGEKLSDQTVLFLGAGSS
CCCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ALGTSDLLVKAMQAEGLSQADARARITMMDVKGLVEPSRTDLSEEQRRYAHAAEPTRDLM
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHHHHCCCHHHHH
ATIRRVRPSVLIGVSTVGGAFTQPVVELMAAINARPIIFPLSIPHSECSAEQAYAWSDGR
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCCC
ALYAAGVQFPQVMRDDHVFRPGQANNFYIFPGLGLAVYATRPRLIPDALIIEAAHALADQ
EEEEECCCCHHHHCCCCEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
VDVTAQARGMLYPPQNQILEVQVTSACRLAEYLFDAGLATVPRPDDIRSWIEGMTYSPTY
HCHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCC
APDA
CCCC
>Mature Secondary Structure
MNRPARHTLRGTALLNDPAFNRGTAFTAAERQTYGLEGLLPPQIETLERQAERALRHLDA
CCCCCCCCEECEEEECCCCCCCCCEEEECCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
KPTDLERYIYLAALVDRNETLFYKVLMSDPARFVPIVYAPTLGEACKAFSHIYRRPRGMY
CCCCHHHHEEEEEEECCCCEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEE
ISLEMKGRIADILRNWPVSDVRFICVTTGGRILGLGDIGANGMGIPIGKLQLYTACGAVP
EEEEECCHHHHHHHCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCCCEEEEHHHCCCC
PQVTLPIQLDIGTTNAALRADPLYLGLRHEPPPQAELDAFVEEFVTAVQEVFPACCIHFE
CCEEEEEEEECCCCCCEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEC
DWKGTDAIRYLERYRERVLCYNDDIQGTASVTLAGLVTALRIKGEKLSDQTVLFLGAGSS
CCCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
ALGTSDLLVKAMQAEGLSQADARARITMMDVKGLVEPSRTDLSEEQRRYAHAAEPTRDLM
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHCCCCCCCCCHHHHHHHHHHHCCCHHHHH
ATIRRVRPSVLIGVSTVGGAFTQPVVELMAAINARPIIFPLSIPHSECSAEQAYAWSDGR
HHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEECCCC
ALYAAGVQFPQVMRDDHVFRPGQANNFYIFPGLGLAVYATRPRLIPDALIIEAAHALADQ
EEEEECCCCHHHHCCCCEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHH
VDVTAQARGMLYPPQNQILEVQVTSACRLAEYLFDAGLATVPRPDDIRSWIEGMTYSPTY
HCHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCC
APDA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA