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The map label for this gene is dfrA [H]

Identifier: 162147410

GI number: 162147410

Start: 1635960

End: 1637051

Strand: Reverse

Name: dfrA [H]

Synonym: GDI_1625

Alternate gene names: 162147410

Gene position: 1637051-1635960 (Counterclockwise)

Preceding gene: 162147413

Following gene: 162147409

Centisome position: 41.51

GC content: 69.32

Gene sequence:

>1092_bases
ATGGTGCCGCATCGTTTCGCCGCCAACCGGCCGCCCCATGGGGGTTTCCCCCGGGACGTCCGCCTGCTGACATATACCGG
AGCATCCGATCGGATCATGACTGCCCCCACGCTTGTTACCGGCGCGACCGGTTTTGTCGGTTCGGCCGTTGCCCGTACGC
TTCTCCAGCGGGGGCATTCGCTGCGCCTGATGGCGCGCAAGGGGGCGGACCTGACCAATATCCGCGACCTGCCGGCGGAA
CTGGTCGAAGGCGACCTGTCCGCGCCCGCCACCTTCGCCGACGCGGTGCGGGGGTGTCGCTACGTCTTCCATGTCGCCGC
CGACTATCGGCTGTGGGTGCCCGACCCCGCGCCCATGATGACCGCGAATGTCGAGGGAACGCGCCGCCTGATGCTGGCGG
CGCAGGACGCGGGGGTGGAACGGATCGTCTATTGCTCGTCGGTCGCGGCGCTGGGGCTGATCGGCGACGGCACCGTGTCG
GACGAGGACACGCCGGTTCACGAGCACGCGGTGATCGGGATCTACAAGCGGTCCAAATACCGGGCGGAGCAGGAGGTCCT
GCGCCTGGTCCGCGAACGCGGCCTGCCGGCGGTGATCGTCAACCCGTCCACCCCCGTGGGCCCGCGCGACATCAAGCCGA
CGCCGACGGGCCAGATGATCCTGGATTGCGCGGCGGGGCGCATGCCGGCCTATGTCGATACCGGGGTGAACATCGTCCAT
GTCGACGACGTGGCCGAGGGCCACGTCCTGGCGCTGGAACGCGGCCGGGCGGGTGAGAAATACATCCTGGGCGGCCAGAA
TTTCCTGCTGCGCGACCTGTTCGCCATGACGGCGGACATCGCGGGCGTGCGGCCGCCGCGCGTCAGCCTGCCGCAATCGG
TGATCTGGCCGGTGGCGGTGGTGTCGGAATGGCTGTCGCGCGGCTTCGGCATCGCCCCGCGCGTCACGCGCGAGATGCTG
GCCATGTCGCACAAGAAGATGTTCTTTTCCTCGGCCAAGGCCGAACGGGAGCTGGGCTATGCCCCGCGCCCGGCGCGCGA
CGCGGTGGCGGATGCCGTGGCCTGGTTCCGCCAGAACGGCATGCTGGGCTAG

Upstream 100 bases:

>100_bases
GCCGCGCCGTGGGACGTCCTGGGCAGGGCGTTCCAGCGCATGGGTTGGGCCTGACTTACACCAGAGGAGGGTCTGGCGCC
ACCATGAGGTGTCGGGATAA

Downstream 100 bases:

>100_bases
GAGCGCGATGGCAATGCTCCTGCTGGCCGTCTCGCTGCTGTGTGCCGCGATCTGGATCGTGCTGATCGGTTTCCATGGAC
GCTTCTGGCAGGGCGGGCCG

Product: dihydroflavonol-4-reductase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MVPHRFAANRPPHGGFPRDVRLLTYTGASDRIMTAPTLVTGATGFVGSAVARTLLQRGHSLRLMARKGADLTNIRDLPAE
LVEGDLSAPATFADAVRGCRYVFHVAADYRLWVPDPAPMMTANVEGTRRLMLAAQDAGVERIVYCSSVAALGLIGDGTVS
DEDTPVHEHAVIGIYKRSKYRAEQEVLRLVRERGLPAVIVNPSTPVGPRDIKPTPTGQMILDCAAGRMPAYVDTGVNIVH
VDDVAEGHVLALERGRAGEKYILGGQNFLLRDLFAMTADIAGVRPPRVSLPQSVIWPVAVVSEWLSRGFGIAPRVTREML
AMSHKKMFFSSAKAERELGYAPRPARDAVADAVAWFRQNGMLG

Sequences:

>Translated_363_residues
MVPHRFAANRPPHGGFPRDVRLLTYTGASDRIMTAPTLVTGATGFVGSAVARTLLQRGHSLRLMARKGADLTNIRDLPAE
LVEGDLSAPATFADAVRGCRYVFHVAADYRLWVPDPAPMMTANVEGTRRLMLAAQDAGVERIVYCSSVAALGLIGDGTVS
DEDTPVHEHAVIGIYKRSKYRAEQEVLRLVRERGLPAVIVNPSTPVGPRDIKPTPTGQMILDCAAGRMPAYVDTGVNIVH
VDDVAEGHVLALERGRAGEKYILGGQNFLLRDLFAMTADIAGVRPPRVSLPQSVIWPVAVVSEWLSRGFGIAPRVTREML
AMSHKKMFFSSAKAERELGYAPRPARDAVADAVAWFRQNGMLG
>Mature_363_residues
MVPHRFAANRPPHGGFPRDVRLLTYTGASDRIMTAPTLVTGATGFVGSAVARTLLQRGHSLRLMARKGADLTNIRDLPAE
LVEGDLSAPATFADAVRGCRYVFHVAADYRLWVPDPAPMMTANVEGTRRLMLAAQDAGVERIVYCSSVAALGLIGDGTVS
DEDTPVHEHAVIGIYKRSKYRAEQEVLRLVRERGLPAVIVNPSTPVGPRDIKPTPTGQMILDCAAGRMPAYVDTGVNIVH
VDDVAEGHVLALERGRAGEKYILGGQNFLLRDLFAMTADIAGVRPPRVSLPQSVIWPVAVVSEWLSRGFGIAPRVTREML
AMSHKKMFFSSAKAERELGYAPRPARDAVADAVAWFRQNGMLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Homo sapiens, GI116268111, Length=373, Percent_Identity=26.5415549597855, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI193211614, Length=347, Percent_Identity=24.4956772334294, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI8393516, Length=347, Percent_Identity=24.4956772334294, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71987463, Length=334, Percent_Identity=30.2395209580838, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 39368; Mature: 39368

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPHRFAANRPPHGGFPRDVRLLTYTGASDRIMTAPTLVTGATGFVGSAVARTLLQRGHS
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCHHCCCCCHHHHHHHHHHHHHCCCC
LRLMARKGADLTNIRDLPAELVEGDLSAPATFADAVRGCRYVFHVAADYRLWVPDPAPMM
EEEEECCCCCCCHHHHCCHHHHCCCCCCCHHHHHHHHHHHEEEEEECCCEEECCCCCCEE
TANVEGTRRLMLAAQDAGVERIVYCSSVAALGLIGDGTVSDEDTPVHEHAVIGIYKRSKY
EECCCCCEEEEEEECCCCCEEEEEHHHHHHHEEECCCCCCCCCCCCCCCEEEEEEHHHHH
RAEQEVLRLVRERGLPAVIVNPSTPVGPRDIKPTPTGQMILDCAAGRMPAYVDTGVNIVH
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEEHHCCCCCEEEECCCEEEE
VDDVAEGHVLALERGRAGEKYILGGQNFLLRDLFAMTADIAGVRPPRVSLPQSVIWPVAV
ECCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
VSEWLSRGFGIAPRVTREMLAMSHKKMFFSSAKAERELGYAPRPARDAVADAVAWFRQNG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
MLG
CCC
>Mature Secondary Structure
MVPHRFAANRPPHGGFPRDVRLLTYTGASDRIMTAPTLVTGATGFVGSAVARTLLQRGHS
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCHHCCCCCHHHHHHHHHHHHHCCCC
LRLMARKGADLTNIRDLPAELVEGDLSAPATFADAVRGCRYVFHVAADYRLWVPDPAPMM
EEEEECCCCCCCHHHHCCHHHHCCCCCCCHHHHHHHHHHHEEEEEECCCEEECCCCCCEE
TANVEGTRRLMLAAQDAGVERIVYCSSVAALGLIGDGTVSDEDTPVHEHAVIGIYKRSKY
EECCCCCEEEEEEECCCCCEEEEEHHHHHHHEEECCCCCCCCCCCCCCCEEEEEEHHHHH
RAEQEVLRLVRERGLPAVIVNPSTPVGPRDIKPTPTGQMILDCAAGRMPAYVDTGVNIVH
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEEHHCCCCCEEEECCCEEEE
VDDVAEGHVLALERGRAGEKYILGGQNFLLRDLFAMTADIAGVRPPRVSLPQSVIWPVAV
ECCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
VSEWLSRGFGIAPRVTREMLAMSHKKMFFSSAKAERELGYAPRPARDAVADAVAWFRQNG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
MLG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]