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The map label for this gene is emrY [H]

Identifier: 162147399

GI number: 162147399

Start: 1621090

End: 1622643

Strand: Reverse

Name: emrY [H]

Synonym: GDI_1614

Alternate gene names: 162147399

Gene position: 1622643-1621090 (Counterclockwise)

Preceding gene: 162147402

Following gene: 162147398

Centisome position: 41.14

GC content: 62.68

Gene sequence:

>1554_bases
GTGACCAGTGGGCAGCGTTCCCTGTTCGGGCTGGCGGGCATCATCGCCCTTGCGTTTGCCACCGAAATGAACGAGCAGGT
TTCGGCACAGGCGCTGCCGGATATCGCGGGGGCCCTGGGCCTTAGCCGCGACCCGCAGCGCTGGTTTTCCTGCCTGTATA
TCACGGCTGAGATCGTGGGGATGTCGGTTTCACCCTGGCTGGCCGTCACCCTGACGTTGCGCCGTTTTTCCCTGGCGGTC
CCCTGGCTGGCCGTGCTGTCCTCCAGCCTGATTCCGCTGACCGGCAATCTGACGCTCCTTTACATCCTGCGTATCTTCCA
GGGGCTGTCCGGTGGGTTTACCGTTCCGCTGCTGATGACGACGGCCCTGCGGGTGCTGCCGCCGCCCATCCGGCTTTACG
GCCTGGCGGCCTATGCCCTGACCGCCACCTTTTTTCCCAGCCTGAGCACGGCCTTTGCGGGCCTGTGGACCGATCTGGTC
GATTGGCGCTTCGTGTTCTGGCAGTCCATTCCGCTCTGCACGATCGCCTTCGTCCTGCTCTGGTATGGAATGCCCGTCGA
ACAACCCCGGCACGAGCGCTTCTGGCGTTTCGACTGGCAGGGGTTCCTGCTTGTCCTGATCGGAATGGGCGCGTTTTCGA
CCATGCTGCAAATCGGCGACTGGATGGACTGGTTCAACAGTCCGGCCATCTGCGTCATGGCGTTGCTCAGTGGGGTCTGC
ATTCCGCTTTTCGTGCTGAACGAATGGTTCCATCCGTTGCCCCTGTTCAAGTTCCAGCTTCTGGAACGACGGAATTTCGC
CTACGGCGCCAGTACCCTGCTGACATTCATGATCATCTCGCTGTCATCTTCCGCCCTGCCGGCGGATTTCCTGCGTGAAG
CCGCCGGATACAGGCCGGAGCAGACCTATCCCATCACCCTGGAAATCGCGGCGATCCAGATCGTCATGCTGCCGCTGATG
GCGGTGCTGCTGAACCGGAAAGGGGTGGATTCCCGTATCGTCAGCCTTATCGGCATGGCCTGCATCCTGACGGCCTGCAT
CGGGGACTTCTTCGTGACGTCCAACTGGAACCGGGACCAGTTCTATCTGTGGCAGGCGTTTCAGGGCGTCGGCAACGCCA
TGATCGTCATGCCGTTGCTGATGATGTCCACCAATGCCCTTGTCCCCGAGGAAGGGCCCTTTGCCTCCGCCATGGTCAAC
ACGCCCCGCGCCGTGGCCGAGGCTGTGGGGATCTGGCTGATCCAGCTTGTCCATCGCGAGCGCGGCGCGCTGCATTCCGA
CCGTATCACCGACCGGCTCGGCCAGGATCGGTTCCAGCTTGTCCAGAGCATGAATCCGGTGCTCCAGCGACCCGCCGCGC
TGACGCCGGACGGGCTGCCGGCCTTTCCCGGCAGCATGACCGCCCTGCACGCGCAGGTCACGCGACAGACCGCGACCCTG
ACCTACAGCGACGACTGGCTCATCATTGCCGGGATCGTGGTGTGCCTGATGGTGTGGGTTTGTGTCCTTCCGGTCCGAAC
CTATCCCCCCCGTATCGTGTTCCAGTCGAAATAG

Upstream 100 bases:

>100_bases
TTTTTGTTATGCCGCACGTGACGCATCTGAGGTTGAAGCGGAGCCTCCCGATCTTTCATAGTCGGCGCATGATGTCTCTT
GCCCCCTCAGGCGCGCCTCG

Downstream 100 bases:

>100_bases
TCCGCGGACGCCCGCCTGTCCCCGTCGGAAGCAGAAAGGAAACATCGCCGCATGGCGGATGAAGACCGGAACGGAAACCG
TGGTCACACGGACAGCAAGC

Product: transporter protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTSGQRSLFGLAGIIALAFATEMNEQVSAQALPDIAGALGLSRDPQRWFSCLYITAEIVGMSVSPWLAVTLTLRRFSLAV
PWLAVLSSSLIPLTGNLTLLYILRIFQGLSGGFTVPLLMTTALRVLPPPIRLYGLAAYALTATFFPSLSTAFAGLWTDLV
DWRFVFWQSIPLCTIAFVLLWYGMPVEQPRHERFWRFDWQGFLLVLIGMGAFSTMLQIGDWMDWFNSPAICVMALLSGVC
IPLFVLNEWFHPLPLFKFQLLERRNFAYGASTLLTFMIISLSSSALPADFLREAAGYRPEQTYPITLEIAAIQIVMLPLM
AVLLNRKGVDSRIVSLIGMACILTACIGDFFVTSNWNRDQFYLWQAFQGVGNAMIVMPLLMMSTNALVPEEGPFASAMVN
TPRAVAEAVGIWLIQLVHRERGALHSDRITDRLGQDRFQLVQSMNPVLQRPAALTPDGLPAFPGSMTALHAQVTRQTATL
TYSDDWLIIAGIVVCLMVWVCVLPVRTYPPRIVFQSK

Sequences:

>Translated_517_residues
MTSGQRSLFGLAGIIALAFATEMNEQVSAQALPDIAGALGLSRDPQRWFSCLYITAEIVGMSVSPWLAVTLTLRRFSLAV
PWLAVLSSSLIPLTGNLTLLYILRIFQGLSGGFTVPLLMTTALRVLPPPIRLYGLAAYALTATFFPSLSTAFAGLWTDLV
DWRFVFWQSIPLCTIAFVLLWYGMPVEQPRHERFWRFDWQGFLLVLIGMGAFSTMLQIGDWMDWFNSPAICVMALLSGVC
IPLFVLNEWFHPLPLFKFQLLERRNFAYGASTLLTFMIISLSSSALPADFLREAAGYRPEQTYPITLEIAAIQIVMLPLM
AVLLNRKGVDSRIVSLIGMACILTACIGDFFVTSNWNRDQFYLWQAFQGVGNAMIVMPLLMMSTNALVPEEGPFASAMVN
TPRAVAEAVGIWLIQLVHRERGALHSDRITDRLGQDRFQLVQSMNPVLQRPAALTPDGLPAFPGSMTALHAQVTRQTATL
TYSDDWLIIAGIVVCLMVWVCVLPVRTYPPRIVFQSK
>Mature_516_residues
TSGQRSLFGLAGIIALAFATEMNEQVSAQALPDIAGALGLSRDPQRWFSCLYITAEIVGMSVSPWLAVTLTLRRFSLAVP
WLAVLSSSLIPLTGNLTLLYILRIFQGLSGGFTVPLLMTTALRVLPPPIRLYGLAAYALTATFFPSLSTAFAGLWTDLVD
WRFVFWQSIPLCTIAFVLLWYGMPVEQPRHERFWRFDWQGFLLVLIGMGAFSTMLQIGDWMDWFNSPAICVMALLSGVCI
PLFVLNEWFHPLPLFKFQLLERRNFAYGASTLLTFMIISLSSSALPADFLREAAGYRPEQTYPITLEIAAIQIVMLPLMA
VLLNRKGVDSRIVSLIGMACILTACIGDFFVTSNWNRDQFYLWQAFQGVGNAMIVMPLLMMSTNALVPEEGPFASAMVNT
PRAVAEAVGIWLIQLVHRERGALHSDRITDRLGQDRFQLVQSMNPVLQRPAALTPDGLPAFPGSMTALHAQVTRQTATLT
YSDDWLIIAGIVVCLMVWVCVLPVRTYPPRIVFQSK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=501, Percent_Identity=25.5489021956088, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789042, Length=499, Percent_Identity=23.6472945891784, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790195, Length=272, Percent_Identity=29.0441176470588, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 57518; Mature: 57386

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
>Mature Secondary Structure 
TSGQRSLFGLAGIIALAFATEMNEQVSAQALPDIAGALGLSRDPQRWFSCLYITAEIVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC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EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]